| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011514610.3 | Gene: | ABCB4 / 5244 | HGNCID: | 45 | Length: | 1384 | Species: | Homo sapiens |
| Alignment Length: | 1301 | Identity: | 564/1301 - (43%) |
|---|---|---|---|
| Similarity: | 787/1301 - (60%) | Gaps: | 62/1301 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 EVSTSSSEGKSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIY 69
Fly 70 SEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFIS 134
Fly 135 GIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHF 199
Fly 200 VYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEIL 264
Fly 265 SSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIID 329
Fly 330 DRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDG 394
Fly 395 KLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDP 459
Fly 460 VFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHE 524
Fly 525 FITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLA 589
Fly 590 SKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYY---NMVRAGDINMPDEVE 651
Fly 652 KEDSIEDTKQKSLALFEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEKPNFFR 716
Fly 717 TFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALRRTAVLSWACLG 781
Fly 782 LAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVDIQ 846
Fly 847 GAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVREKQVIE 911
Fly 912 EACRIATESITNIRTVAGLRREADVIREYTEEI---QRVEVLIRQKLRWRGVLNSTMQASAFFAY 973
Fly 974 AVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHRLFQILDRKPKI 1038
Fly 1039 QSPMGTIKNTLAKQLNLFEG-VRYRGIQFRYPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKST 1102
Fly 1103 CVQLLQRYYDPDEGTIHIDHD----DIQH--DLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDN 1161
Fly 1162 RRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDE 1226
Fly 1227 ATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGI 1291
Fly 1292 Y 1292 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 542/1215 (45%) |
| ABC_membrane | 108..354 | CDD:279056 | 81/245 (33%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 142/239 (59%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 103/272 (38%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 153/240 (64%) | ||
| ABCB4 | XP_011514610.3 | AAA | 108..1369 | CDD:333001 | 564/1301 (43%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 196 | 1.000 | Domainoid score | I3116 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H136368 | |
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1700 |
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.710 | |||||