Protein Alignment Mdr65 and CG3156

DIOPT Version :9

• Sequence 1: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 199/603 - (33%)
• Similarity: 304/603 - (50%)
• Gaps: 46/603 - (7%)

  Fly   718 FSRILQLAKQE-W-------CYLILGTISAVAVGFLYPAFAVIF---GEFYAALAEKDPEDALRR 771
            :.|:|.|.|.| |       |.::...|:.....||.....|:|   |...||:|:      |..
  Fly   109 YGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAK------LGE 167

  Fly   772 TAVLSWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSA 836
            .:||   ..|:..|.|...|.:.:||..|.:.:...:|:..:.:|:.|||||||  ....|.|..
  Fly   168 YSVL---LFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFD--TKGTGELIN 227

  Fly   837 RLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMSN 901
            |||.:.:.:..::...:|..:::::.......:.:|.:.:||.:.....|.:.|..|:..:.:..
  Fly   228 RLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRR 292

  Fly   902 AVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVLNSTMQ 966
            ....|.....|..:.|.|...|::||....||...:..:..::.....:..::.|.|.:......
  Fly   293 ITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLTG 357

  Fly   967 ASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLA--------FTPAFSAALI 1023
            ....|.....|.|||.||      .||.:.:.  .|...|:.|..:|        |....:..:.
  Fly   358 FCGNFIIISVLYYGGTLV------LQDSLTIG--ALTAFMLYAGYVAISMNGLSNFYSQLNKGIG 414

  Fly  1024 AGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGLDLEVLKGQ 1088
            |..|:::||||:..|....|.:  .|.|.:.   .|.::.:.|.:||||::.:|....|.::.|.
  Fly   415 ASERIWEILDRECSIPIDKGVV--PLEKPVG---EVGFQNVFFTFPTRPESAVLTDFSLNLMPGT 474

  Fly  1089 TVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIA 1153
            |.|:||.||.||:|...|:.|.|||..||:|:|..|:: .:....:|..:|.|||||.||..||.
  Fly   475 TTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLR-TVNPQWLRNNIGAVSQEPVLFSCSIR 538

  Fly  1154 ENIAYGDN-RRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVR 1217
            |||.||.| ..:.|...:....:.||...|...||:|.||.:|.||..||||||||:||||||::
  Fly   539 ENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIK 603

  Fly  1218 NPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNH 1282
            ||.||:|||||||||..||.|||.|||....|||.:.|||||||::|||.|.|:.:|::||||::
  Fly   604 NPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSY 668

  Fly  1283 MQLIS-QGGIYAKLHKTQ 1299
            .:|:. |.|::.:|..:|
  Fly   669 NELMGIQEGVFRELVASQ 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr65	NP_476831.1	PTZ00265	91..1300	CDD:240339	199/603 (33%)
		ABC_membrane	108..354	CDD:279056
		ABC_MTABC3_MDL1_MDL2	405..642	CDD:213216
		ABC_membrane	736..1006	CDD:279056	61/272 (22%)
		ABC_MTABC3_MDL1_MDL2	1059..1299	CDD:213216	116/241 (48%)
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	199/603 (33%)
		ABC_membrane	127..395	CDD:279056	64/286 (22%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	115/239 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I220
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	P	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910