| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036822.1 | Gene: | Abcb4 / 24891 | RGDID: | 620248 | Length: | 1278 | Species: | Rattus norvegicus |
| Alignment Length: | 1320 | Identity: | 553/1320 - (41%) |
|---|---|---|---|
| Similarity: | 777/1320 - (58%) | Gaps: | 88/1320 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 ERDEVSTSSSEGKSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVV 66
Fly 67 IIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVM 131
Fly 132 FISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKV 196
Fly 197 GHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAE 261
Fly 262 EILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNL 326
Fly 327 IIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLS 391
Fly 392 TDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRF 456
Fly 457 YDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAG 521
Fly 522 AHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQAL 586
Fly 587 DLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYY---NMVRAGDINMPD 648
Fly 649 EVEKEDSIEDTKQK--------SLALFEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNAQSA 705
Fly 706 EAPPEKPNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALR 770
Fly 771 RTAVLSWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALS 835
Fly 836 ARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMS 900
Fly 901 NAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQ---RVEVLIRQKLRWRGVLN 962
Fly 963 STMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHR 1027
Fly 1028 LFQILDRKPKIQS-------PMGTIKNTLAKQLNLFEG-VRYRGIQFRYPTRPDAKILNGLDLEV 1084
Fly 1085 LKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFE 1149
Fly 1150 RSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARA 1214
Fly 1215 LVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQ 1279
Fly 1280 GNHMQLISQGGIYAKLHKTQ 1299 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 530/1231 (43%) |
| ABC_membrane | 108..354 | CDD:279056 | 80/245 (33%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 138/239 (58%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 100/272 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 150/239 (63%) | ||
| Abcb4 | NP_036822.1 | PTZ00265 | 29..1271 | CDD:240339 | 549/1307 (42%) |
| ABC_membrane | 58..342 | CDD:279056 | 96/302 (32%) | ||
| ABC_MTABC3_MDL1_MDL2 | 392..628 | CDD:213216 | 137/235 (58%) | ||
| Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385 | 622..646 | 6/25 (24%) | |||
| ABC_membrane | 714..984 | CDD:279056 | 100/272 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1033..1272 | CDD:213216 | 150/239 (63%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 194 | 1.000 | Domainoid score | I3071 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H136368 | |
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.730 | |||||