| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032856.2 | Gene: | Abcb4 / 18670 | MGIID: | 97569 | Length: | 1276 | Species: | Mus musculus |
| Alignment Length: | 1307 | Identity: | 558/1307 - (42%) |
|---|---|---|---|
| Similarity: | 786/1307 - (60%) | Gaps: | 67/1307 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 EVSTSSSEGKSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIY 69
Fly 70 SEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFIS 134
Fly 135 GIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHF 199
Fly 200 VYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEIL 264
Fly 265 SSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIID 329
Fly 330 DRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDG 394
Fly 395 KLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDP 459
Fly 460 VFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHE 524
Fly 525 FITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLA 589
Fly 590 SKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYY---NMVRAGDINMPDEVE 651
Fly 652 KEDSIEDTKQKSLALFEKSFETSPLN-----FEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEK 711
Fly 712 PNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALRRTAVLS 776
Fly 777 WACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGE 841
Fly 842 AVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVRE 906
Fly 907 KQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQ---RVEVLIRQKLRWRGVLNSTMQAS 968
Fly 969 AFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHRLFQILD 1033
Fly 1034 RKPKIQSPMGTIKNTLAKQLNLFEG-VRYRGIQFRYPTRPDAKILNGLDLEVLKGQTVALVGHSG 1097
Fly 1098 CGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNR 1162
Fly 1163 RSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEA 1227
Fly 1228 TSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIY 1292
Fly 1293 AKLHKTQ 1299 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 536/1221 (44%) |
| ABC_membrane | 108..354 | CDD:279056 | 81/245 (33%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 141/239 (59%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 101/272 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 149/239 (62%) | ||
| Abcb4 | NP_032856.2 | PTZ00265 | 30..1269 | CDD:240339 | 554/1293 (43%) |
| ABC_membrane | 58..342 | CDD:279056 | 96/302 (32%) | ||
| ABC_MTABC3_MDL1_MDL2 | 392..628 | CDD:213216 | 140/235 (60%) | ||
| Interaction with HAX1. /evidence=ECO:0000250 | 622..646 | 7/25 (28%) | |||
| ABC_membrane | 712..982 | CDD:279056 | 101/272 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1031..1270 | CDD:213216 | 149/239 (62%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 198 | 1.000 | Domainoid score | I3072 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H136368 | |
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1700 |
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.710 | |||||