| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_510126.1 | Gene: | pgp-12 / 181415 | WormBaseID: | WBGene00004006 | Length: | 1318 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1335 | Identity: | 464/1335 - (34%) |
|---|---|---|---|
| Similarity: | 699/1335 - (52%) | Gaps: | 158/1335 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 29 EPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLV----------DRAMQF 83
Fly 84 GTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFISGIFSVDVFNMVALR 148
Fly 149 QVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAIS 213
Fly 214 FSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKS 278
Fly 279 EVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNL----IIDDRNVENKEYT 339
Fly 340 PAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDG-KLLNYGLRG 403
Fly 404 DVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDD 468
Fly 469 LDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESY 533
Fly 534 RSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVV 598
Fly 599 SHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEK--EDSIEDTKQ 661
Fly 662 ------------------KSLAL------FEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNA 702
Fly 703 QSAEAPPEKPNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPED 767
Fly 768 ALRRTAVLSWACLGLAFL----TGLVCFLQTY----LFNYAGIWLTTRMRAMTFNAMVNQEVGWF 824
Fly 825 DDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIV 889
Fly 890 GS--VILEAKM---MSNAVVRE--KQV-IEEACRIATESITNIRTVAGLRREADVIREYTEEIQR 946
Fly 947 VEVLIRQKLRWR-----GVLNSTMQASAFFAYAVALCYG-GV-LVSEGQLPFQDIIKVSETLLYG 1004
Fly 1005 SMMLAQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYP 1069
Fly 1070 TRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGV 1134
Fly 1135 RTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGT 1199
Fly 1200 QLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQN 1264
Fly 1265 ADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQ 1299 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 445/1263 (35%) |
| ABC_membrane | 108..354 | CDD:279056 | 61/249 (24%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 129/236 (55%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 69/292 (24%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 126/239 (53%) | ||
| pgp-12 | NP_510126.1 | ABC_membrane | 97..332 | CDD:279056 | 67/271 (25%) |
| PTZ00265 | 145..1312 | CDD:240339 | 439/1230 (36%) | ||
| ABC_MTABC3_MDL1_MDL2 | 417..654 | CDD:213216 | 129/236 (55%) | ||
| ABC_membrane | 762..1005 | CDD:294371 | 65/267 (24%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1077..1314 | CDD:213216 | 129/244 (53%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1700 |
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24221 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.740 | |||||