| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_502413.1 | Gene: | pgp-1 / 178215 | WormBaseID: | WBGene00003995 | Length: | 1321 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1332 | Identity: | 501/1332 - (37%) |
|---|---|---|---|
| Similarity: | 753/1332 - (56%) | Gaps: | 85/1332 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 ERDEVSTSSSEGKSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVV 66
Fly 67 IIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVM 131
Fly 132 FISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKV 196
Fly 197 G-HFVYL---VVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAG 257
Fly 258 NLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWY 322
Fly 323 GVNLIID-DRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSK 386
Fly 387 IDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQ 451
Fly 452 LLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAA 516
Fly 517 ATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQ 581
Fly 582 VQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRA----- 641
Fly 642 -------GDINMPDEVEKEDS-----------IEDTKQKSLALFEKSFETSPLNFEKGQKNSVQF 688
Fly 689 EEPIIKALIKDTNAQSAEAPPEKPNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIF 753
Fly 754 GEFYAALAEKDPEDALRRTAVLSWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVN 818
Fly 819 QEVGWFDDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLA 883
Fly 884 NCPIIVGSVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEI---- 944
Fly 945 -QRVEVLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMML 1008
Fly 1009 AQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPD 1073
Fly 1074 AKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKL 1138
Fly 1139 GIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSG 1203
Fly 1204 GQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVI 1268
Fly 1269 CVIQNGQVVEQGNHMQLISQGGIYAKLHKTQK 1300 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 481/1241 (39%) |
| ABC_membrane | 108..354 | CDD:279056 | 74/250 (30%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 140/248 (56%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 69/274 (25%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 145/239 (61%) | ||
| pgp-1 | NP_502413.1 | PTZ00265 | 38..1311 | CDD:240339 | 495/1322 (37%) |
| ABC_membrane | 81..367 | CDD:279056 | 84/307 (27%) | ||
| ABC_MTABC3_MDL1_MDL2 | 416..653 | CDD:213216 | 139/236 (59%) | ||
| ABC_membrane | 760..1028 | CDD:279056 | 69/271 (25%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1077..1316 | CDD:213216 | 148/242 (61%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 191 | 1.000 | Domainoid score | I1904 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm4744 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24221 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.790 | |||||