| Sequence 1: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001300410.1 | Gene: | pgp-2 / 172262 | WormBaseID: | WBGene00003996 | Length: | 1296 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1333 | Identity: | 495/1333 - (37%) |
|---|---|---|---|
| Similarity: | 742/1333 - (55%) | Gaps: | 93/1333 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 ERDEVSTSSSEGKSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVV 66
Fly 67 IIYSEFTSMLVDRAMQ----FGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIA 127
Fly 128 SVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGI 192
Fly 193 SEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAG 257
Fly 258 NLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWY 322
Fly 323 GVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKI 387
Fly 388 DPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQL 452
Fly 453 LQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAA 517
Fly 518 TQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQV 582
Fly 583 QQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMP 647
Fly 648 DEVEKEDSIEDT---------KQKSLALFEKSFETS------------PLNFEKGQKNSVQFEEP 691
Fly 692 IIKALIKDTNAQSAEAPPEKPNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEF 756
Fly 757 YAALAEKDPEDALRRTAVLSW----ACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMV 817
Fly 818 NQEVGWFDDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFIS---SVSVAMYYNWKLAL 879
Fly 880 LCLANCPIIVGSVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEI 944
Fly 945 QRVEVLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLA 1009
Fly 1010 QSLAFTPAFSAALIAGHRLFQILDRKPKIQ--SPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRP 1072
Fly 1073 DAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTK 1137
Fly 1138 LGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLS 1202
Fly 1203 GGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADV 1267
Fly 1268 ICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQK 1300 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 475/1238 (38%) |
| ABC_membrane | 108..354 | CDD:279056 | 77/245 (31%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 132/236 (56%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 63/276 (23%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 141/239 (59%) | ||
| pgp-2 | NP_001300410.1 | PTZ00265 | 56..1286 | CDD:240339 | 484/1281 (38%) |
| ABC_membrane | 61..349 | CDD:279056 | 88/305 (29%) | ||
| ABC_MTABC3_MDL1_MDL2 | 399..632 | CDD:213216 | 131/232 (56%) | ||
| ABC_membrane | 736..999 | CDD:279056 | 63/271 (23%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1052..1290 | CDD:213216 | 141/239 (59%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 189 | 1.000 | Domainoid score | I1944 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm4744 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24221 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 12 | 11.820 | |||||