Protein Alignment Mdr65 and tap2

DIOPT Version :9

• Sequence 1: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: XP_002942649.3
• Gene: tap2 / 100489020
• XenbaseID: XB-GENE-481680
• Length: 728
• Species: Xenopus tropicalis
• Alignment Length: 650
• Identity: 197/650 - (30%)
• Similarity: 327/650 - (50%)
• Gaps: 94/650 - (14%)

  Fly     4 DEVSTSSSEGKSQEEAPMAEGLEPTEPIAFLK-----------LFRFSTYGEIGWLFFGFIMCCI 57
            |.||.:....||.|....::..|....|..||           .|.|.|...||.:|..:.|..:
 Frog   128 DLVSPNILPNKSAEGEANSKKRERENFIRLLKYSIPDWLPLCGAFVFLTLALIGEMFIPYYMGRV 192

  Fly    58 KALTLPAVVIIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGI 122
                   :.|:.:.:......|||.|....::.: .:|.|.:
 Frog   193 -------IDILSTNYNEREFLRAMSFMAMFSITS-SIFAGSR----------------------- 226

  Fly   123 LLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEK 187
                       .|:|   :|::..|.|  |:|:.||.|||:|:|.:.:.....:.|..:.:|..:
 Frog   227 -----------GGLF---MFSLARLTQ--RLRLLLFRSVIKQEIAFFEATKSGDITSRLTNDTAR 275

  Fly   188 IRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLA--VSSYIPLVI--LLNYYVAKFQGKLTAR 248
            :...|:..|...:.::|..:...:..||..|:|||.  :||.:..:|  :.|||    ...|..|
 Frog   276 VSRSIAANVNITLRMLVKCVGVYSFMFSLSWQLTLLTFISSPLTWIIQKVYNYY----HQDLVKR 336

  Fly   249 EQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLK---- 309
            .|:|.|.:..||:||:.|:|.|.||..|:.|.:||||.|.........:...:.|...|.:
 Frog   337 VQDSIARSSELAKEIIESVRNVYSFAAEEEEAKRYENSLQETHVLQTRRDFVTALYLLVTRLVNL 401

  Fly   310 ----SMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIART-APFLESFAT 369
                :|||        ||..||       ...:..:..|::|....:.:|:..|| ...|.....
 Frog   402 GTQVTMLY--------YGQILI-------RSGFISSGKMVSFILYQMESDSYIRTLVHMLSEITH 451

  Fly   370 ARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQ 434
            |.|.|..:|:.:|...::   |..|.|....|:|..||.:|.|.||||||::..:.::..:..|.
 Frog   452 AAGAAEKVFQYLDREPQV---SASGCLCPGTLQGRFEFSNVTFSYPSRPEILALQNVSFTLPPGS 513

  Fly   435 TVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQ 499
            ..||||.||.||:|||.||:|||:|..|::|||...:::|..::|.|.:|:|.||||||.|::.:
 Frog   514 VTALVGPSGGGKTTCVSLLERFYEPQGGNILLDGKPLKEYKHEYLHSKVALVAQEPVLFAGSVRE 578

  Fly   500 NISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKI 564
            |||||.....:::::|||.:|.|.:||..:.::|.:.:|..|:|||.|||||:|:||||.:.||:
 Frog   579 NISYGLYNIPEEKLKAAARKAKAEDFIEGMEKAYDTDVGNSGAQLSAGQKQRVALARALARKPKL 643

  Fly   565 LLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLM 629
            |:||||:|.||.::|.::|::|. :.:..:.::::|||..::.||:|:.:..|.::|:|:|:.|:
 Frog   644 LILDEASSCLDAETEHEIQKSLQ-SIEDLSLLIIAHRLRTVQKADQILVLEAGNLVEQGTHEKLV 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr65	NP_476831.1	PTZ00265	91..1300	CDD:240339	175/551 (32%)
		ABC_membrane	108..354	CDD:279056	63/257 (25%)
		ABC_MTABC3_MDL1_MDL2	405..642	CDD:213216	96/224 (43%)
		ABC_membrane	736..1006	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1059..1299	CDD:213216
tap2	XP_002942649.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910