Protein Alignment CG10226 and MDL2

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_015053.2
• Gene: MDL2 / 855858
• SGDID: S000006191
• Length: 773
• Species: Saccharomyces cerevisiae
• Alignment Length: 650
• Identity: 198/650 - (30%)
• Similarity: 313/650 - (48%)
• Gaps: 101/650 - (15%)

  Fly   713 NQEIDDPRVPSANFIS-------------------TFFRILGWARPEWSFLIIGAI-----CAGL 753
            ::.:.:..:|||:.||                   ...|:...|:.:|..|:...:     |:
Yeast    69 SKTVPETSLPSASPISKGSARSAHAKEQSKTDDYKDIIRLFMLAKRDWKLLLTAILLLTISCS-- 131

  Fly   754 YGVTMP-VFSVVLAEL-------YGSLAKPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFN 810
            .|:::| |..:||..|       :..|..|.....|.:..|...::|:||.||....:|   ...
Yeast   132 IGMSIPKVIGIVLDTLKTSSGSDFFDLKIPIFSLPLYEFLSFFTVALLIGCAANFGRFI---LLR 193

  Fly   811 LAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNF 875
            :....:..|:|:...:..::|:..:||  .:.:|.|.:||..||..|..::...:|:.::|....
Yeast   194 ILSERVVARLRANVIKKTLHQDAEFFD--NHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICG 256

  Fly   876 ICSIAIAFPYSWELALICLSTSPFMVASIVFEAR-FGEKSALKEKEVLEET---SRIATETITQI 936
            :..:.:....|.:|:::.|    |....::|.|. ||::.....|::.|.|   :|:|.|.::.|
Yeast   257 VVGVGMMCSLSPQLSILLL----FFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGI 317

  Fly   937 RTVAGLRREEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMF--------------FGYAV 987
            :||.....|       ..|:.||...|..       :..:||:..|              ..:..
Yeast   318 KTVQSFVAE-------GNELSRYNVAIRD-------IFQVGKTAAFTNAKFFTTTSLLGDLSFLT 368

  Fly   988 TLTYGGHMCADGKIKFETIMKISNTMLY----GLFILAQSLAFTPAFNAALLSANRMYEIIDRKP 1048
            .|.||.::....::   :|..::..|||    |..:...|..::.....| .:|:|::|:.||||
Yeast   369 VLAYGSYLVLQSQL---SIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGA-GAASRLFELTDRKP 429

  Fly  1049 QIQSPESFEIQQNGNGTAYKTNVVQQGV-SYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGA 1112
            .| ||..        |..||.:   :|| .::.::||||:||.:::.:|.|..|..|.:|.:||.
Yeast   430 SI-SPTV--------GHKYKPD---RGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGP 482

  Fly  1113 SGSGKSTCVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGD 1177
            ||.||||...||:|||:|..|.|.||.:.| ..::.|:|||.:|||.|||.|...:|.|||.||.
Yeast   483 SGRGKSTIALLLLRYYNPTTGTITIDNQDI-SKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGL 546

  Fly  1178 TSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLD 1242
            |.... .::|...||....|.||...|..||||:|..||.||||||||||||||:::.|.||:||
Yeast   547 TYTPT-KEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILD 610

  Fly  1243 EATSALDFQSERVVQQALDSACSGR--TCIVIAHRLSTIQNA-NVICVIQAGKIVEQGSHSQLLA 1304
            |||||||.:||..:..........:  |.:.||||||||:.: |||.:...|.:||.|...:|.|
Yeast   611 EATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYA 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	197/649 (30%)
		ABC_membrane	<147..333	CDD:279056
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216
		ABC_membrane	749..1019	CDD:279056	64/304 (21%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	108/232 (47%)
MDL2	NP_015053.2	3a01208	1..685	CDD:273363	197/649 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I944
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810