Protein Alignment CG10226 and ABCB6

DIOPT Version :10

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_181480.1
• Gene: ABCB6 / 818533
• AraportID: AT2G39480
• Length: 1407
• Species: Arabidopsis thaliana
• Alignment Length: 1408
• Identity: 408/1408 - (28%)
• Similarity: 697/1408 - (49%)
• Gaps: 169/1408 - (12%)

  Fly    12 AADADEATPAAQKKKKTKEKAQP---MVSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVV 73
            ||.||:     :::.:..|:.:|   .|.:::||.....:|:::::.|.|||....    .|::|
plant    47 AAQADD-----EEEMEEPEEMEPPPAAVPFSQLFACADRFDWVLMVFGSVAAAAHG----TALIV 102

  Fly    74 YSELVAMFIERTLGQGTSSVTIGLSLFGGGKILTNASYEENMQELRKDSVSFGILMTLNTLLMLF 138
            |....|                        ||:...::..:...|..|. .|..|:.|:..::..
plant   103 YLHYFA------------------------KIVQVLAFPTDSDHLISDD-QFNRLLELSLTIVYI 142

  Fly   139 SGVYYVDAFNRLAL------KLTVRMRREFFKATLRQEIGWHD-MAKDQNFAVRITDNMEKIRSG 196
            :|..::..:..::.      :.|..:|.::.:..|.|::.:.| ...:.:...::..::..|:|.
plant   143 AGGVFISGWIEVSCWILTGERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSA 207

  Fly   197 IAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRA 261
            ::|.:|:|:..|...|..:::.|:..|::||..:...|..:........:..:|....|.:|..|
plant   208 LSEKVGNYIHNMATFISGLIIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEA 272

  Fly   262 SSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFW 326
            :|:.|:.:..:||:.||..|......|.:.|:..|:.|.......||.......:...:.|...|
plant   273 ASIAEQAVSYVRTLYAFTNETLAKYSYATSLQATLRYGILISLVQGLGLGFTYGLAICSCAMQLW 337

  Fly   327 YGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVID 391
            .|...::::|     .:..|...|:..:::||:  ..||.:..   ..:|...|.:|..:.::|.
plant   338 IGRFFVIHHR-----ANGGEIITALFAVILSGL--GLNQAATN---FYSFDQGRIAAYRLFEMIS 392

  Fly   392 RTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKS 456
            |:|  ...::.|.||: .::|.:|||:|:|.|.:|.::.:|.|..:.|...:.|||||.:|.|||
plant   393 RSS--SGTNQEGIILS-AVQGNIEFRNVYFSYLSRPEIPILSGFYLTVPAKKAVALVGRNGSGKS 454

  Fly   457 TCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKE 521
            :.|.|::|||||..|:||||||:::...::||||.|.:|.|||.|...||.|||.:|: :||..:
plant   455 SIIPLMERFYDPTLGEVLLDGENIKNLKLEWLRSQIGLVTQEPALLSLSIRENIAYGR-DATLDQ 518

  Fly   522 VEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYH 586
            :|:|||.|:||.||.:|.|||:|.:.:.|:.|:..|:.:::||||::..|.||||||.|..||:.
plant   519 IEEAAKKAHAHTFISSLEKGYETQVGKTGLTLTEEQKIKLSIARAVLLDPTILLLDEVTGGLDFE 583

  Fly   587 SEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKLEGFYHKM---- 647
            :|::||.|||....||:|::::.|||.||:|..|..:|.|:.:|.|||:||:.|...|.::
plant   584 AERVVQEALDLLMLGRSTIIIARRLSLIRNADYIAVMEEGQLLEMGTHDELINLGNLYAELLKCE 648

  Fly   648 --------VTVHSYDDSA-------------------------------EELLNELEEVAEIKER 673
                    :.|.:|:|||                               ..:....|.....:|.
plant   649 EATKLPRRMPVRNYNDSAAFQAERDSSAGRGFQEPSSPKMAKSPSLQRGHNVFRSQELCFNSEES 713

  Fly   674 KMSYEVEPYQLGTRNSIV-------SLEKNAEFQMKNLNGLANITM------NQEIDDPRVPSAN 725
            ...:...|.:||...|.:       ::::...|:|: |..|..|.:      .....||..|.:.
plant   714 PNDHSPAPEKLGENGSSLDVGEKEPTIKRQDSFEMR-LPELPKIDIQCPQRQKSNGSDPESPISP 777

  Fly   726 FI-----------STFFRILG-----------------------W-----ARPEWSFLIIGAICA 751
            .:           .||.|.||                       |     :.|||.:.::|:|.|
plant   778 LLISDPQNERSHSQTFSRPLGHSDDTSASVKVAKDGQHKEPPSFWRLAQLSFPEWLYAVLGSIGA 842

  Fly   752 GLYGVTMPVFSVVLAELYGSLAKPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWL 816
            .::|...|:.:.|:|.:..:........:.|:.....:|...:||...|..::|.|:|.:.|..:
plant   843 AIFGSFNPLLAYVIALVVTTYYTSKGSHLREEVDKWCLIIACMGIVTVVANFLQHFYFGIMGEKM 907

  Fly   817 TTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAI 881
            |.|:|...|..::..|:||:|.:|||...||.||:.||..|:.|....||..||.....|.:|.|
plant   908 TERVRRMMFSAMLRNEVGWYDEEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSFAVIVAILI 972

  Fly   882 AFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREE 946
            .....|.|||:.|:|.|.:..|.:.:..:....:...:|:..:.|.:..:.:..|.||.......
plant   973 GLLLGWRLALVALATLPVLTLSAIAQKLWLAGFSKGIQEMHRKASLVLEDAVRNIYTVVAFCAGN 1037

  Fly   947 ELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKISN 1011
            :::::|..:::|...|........|......:.|:|...|:.|.|.........:|..|.:....
plant  1038 KVMELYRLQLQRILRQSFFHGMAIGFAFGFSQFLLFACNALLLWYTALSVDRRYMKLSTALTEYM 1102

  Fly  1012 TMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQSPESFEIQQNGNGTAYKTNVVQQGV 1076
            ...:..|.|.:.....|.......|...::|||||.|.|:..::         :|.....|...:
plant  1103 VFSFATFALVEPFGLAPYILKRRRSLASVFEIIDRVPTIEPDDT---------SALSPPNVYGSI 1158

  Fly  1077 SYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQES 1141
            ..:.::|.||:||.:.||.||:|.:|.|||||:||.|||||||.:.|:.|||||..|::|:|...
plant  1159 ELKNIDFCYPTRPEVLVLSNFSLKVNGGQTVAVVGVSGSGKSTIISLIERYYDPVAGQVLLDGRD 1223

  Fly  1142 IHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYG-DTSRQVPMQQIIEAAKMANAHEFIMSLPA 1205
            : ...:|:.||..:|::.|||.:|..:|.:||.|. ..:.:..|:   |||::||||.||.|||.
plant  1224 L-KSYNLRWLRSHMGLIQQEPIIFSTTIRENIIYARHNASEAEMK---EAARIANAHHFISSLPH 1284

  Fly  1206 QYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSG-RTC 1269
            .|||.:|.:|.:|:.||||||||||.:::|..|||:|||:|:::.:|.||||:|||:...| :|.
plant  1285 GYDTHIGMRGVELTQGQKQRIAIARVVLKNAPILLIDEASSSIESESSRVVQEALDTLIMGNKTT 1349

  Fly  1270 IVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKL 1312
            |:||||::.:::.:.|.|:..|||||:|:|..|..|||:|.:|
plant  1350 ILIAHRVAMMRHVDNIVVLNGGKIVEEGTHDCLAGKNGLYVRL 1392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	MdlB	147..652	CDD:440747	163/523 (31%)
		MdlB	723..1320	CDD:440747	201/631 (32%)
ABCB6	NP_181480.1	MdlB	83..644	CDD:440747	178/603 (30%)
		MdlB	820..1392	CDD:440747	195/584 (33%)