Protein Alignment CG10226 and ABCB9

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_062571.1
• Gene: ABCB9 / 23457
• HGNCID: 50
• Length: 766
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 206/626 - (32%)
• Similarity: 329/626 - (52%)
• Gaps: 93/626 - (14%)

  Fly   728 STFFRILGWARPEWSFLIIGA---ICAGLYGVTMPVFS------VVLAELYGSLAKPTDEEVLEQ 783
            :|..::|.:.:|:.:||:..:   |.|.|....:|.::      :|:            ::.::|
Human   172 ATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVI------------QKSMDQ 224

  Fly   784 SASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSA 848
            .::..:|..::.|.:.....|:...|.|....|..|:|:..||.:::||..:||  ||..|.|.:
Human   225 FSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFD--ENRTGDLIS 287

  Fly   849 RLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTSP--FMVASIVFEARFG 911
            ||:.|...|...:...::..::........:...|..||:|:|:.....|  .||::|     :|
Human   288 RLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNI-----YG 347

  Fly   912 EKSALKEKEV---LEETSRIATETITQIRTVAGLRREEELIKIY-----------DKEVERYRHQ 962
            :......|||   |...|..|.|||:.::||.....|||..::|           .||...|.:.
Human   348 KYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYY 412

  Fly   963 ILSRLKWRGLVNSLGKSLMFFGYAVT-LTYGGHMCADGKIKFETIMKISNTMLYGL--FILAQSL 1024
            :     |       |..|......|: |.||||:...|:      |...|.:.:.:  |:|...:
Human   413 V-----W-------GSGLTLLVVQVSILYYGGHLVISGQ------MTSGNLIAFIIYEFVLGDCM 459

  Fly  1025 AFTPAFNAALL----SANRMYEIIDRKPQI-----QSPESFEIQQNGNGTAYKTNVVQQGVSYRG 1080
            ....:..:.|:    :|.:::|.|||:|.:     .:|:..|.:                |.:..
Human   460 ESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGR----------------VDFEN 508

  Fly  1081 LNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHHD 1145
            :.|:|.:|||.:||||.:..::.|:..||||.||||||:||.:|..:|..:.|::|:|.:.| ..
Human   509 VTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPI-SA 572

  Fly  1146 MDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTV 1210
            .|.|.|.|.:.:|||||.||.:||.|||.||..:  ||.:.::|||:.||||.|||.|...|.|.
Human   573 YDHKYLHRVISLVSQEPVLFARSITDNISYGLPT--VPFEMVVEAAQKANAHGFIMELQDGYSTE 635

  Fly  1211 LGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSGRTCIVIAHR 1275
            .|.||.|||||||||:|:|||:||||.:|:|||||||||.:||.::|||:.......|.::||||
Human   636 TGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHR 700

  Fly  1276 LSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYRCQ 1316
            |||:::|::|.|:..|::|:||:|.||||:.|:|:||.:.|
Human   701 LSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQ 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	203/619 (33%)
		ABC_membrane	<147..333	CDD:279056
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216
		ABC_membrane	749..1019	CDD:279056	68/294 (23%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	121/239 (51%)
ABCB9	NP_062571.1	3a01208	44..738	CDD:273363	204/621 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810