Protein Alignment CG10226 and Abcc10

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_001334325.1
• Gene: Abcc10 / 224814
• MGIID: 2386976
• Length: 1526
• Species: Mus musculus
• Alignment Length: 1428
• Identity: 319/1428 - (22%)
• Similarity: 546/1428 - (38%)
• Gaps: 350/1428 - (24%)

  Fly    29 KEKAQPMVSYTELFRYIAGWDYLVL--------LSGFVAAFLQSLVFPIAIVVYSELVAMFIERT 85
            ||.||   .:..|:|.. |..||.|        :.||....|.||           ||. |:|
Mouse   269 KEGAQ---LWRALYRAF-GCCYLALGLLKMVGTMLGFSGPLLLSL-----------LVG-FLE-- 315

  Fly    86 LGQGTSSVTIGLSL---FGGGKILTNASYEENMQELRKDSVSFGILMTLNTLLMLFSGVYYVDAF 147
              :|...::.||..   ..||.:::.....:...|:||        :||...:.:.|.:|
Mouse   316 --EGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRK--------VTLQARVAVLSTLY----- 365

  Fly   148 NRLALKLTVRMRREFFKATLRQEIG------WHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVE 206
             |.||||          ...|...|      ..|..:..|||           ....|..|..::
Mouse   366 -RKALKL----------GPSRPPTGEVLNLLGTDSERLLNFA-----------GSFHEAWGLPLQ 408

  Fly   207 IMCDVII---SVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRAS-SVVEE 267
            :...:.:   .|.::|:.|..|||.:|   |:..|:.:.:     ..:.||...:..|. .::.|
Mouse   409 LAITLYLLYQQVGMAFLAGLVLALLLV---PVNKVIATRI-----MASNQEMLRHKDARVKLMTE 465

  Fly   268 VIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWK--GAFSGLSDTVMKAMLFITGAGSFWYGAN 330
            ::..||.:..|        |::..|...:||.:.|  |.        ::.:.::..|..:.:.|
Mouse   466 LLSGIRVIKFF--------RWEQALGDRVKACRTKELGR--------LRVIKYLDAACVYLWAA- 513

  Fly   331 LILYYRDPSIPIDEREYTPAVVMIVI-SGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTS 394
                             .|.|:.|.| ...::..:|::.|..| ...|:.|             .
Mouse   514 -----------------LPVVICITIFITYVLMGHQLTATKVF-TALALVR-------------M 547

  Fly   395 LIDPLSKAGKILNYGLKG--------------------------------AVEFRDVFFRYP--- 424
            ||.||:....::|..|:.                                |:|..:..|.:.
Mouse   548 LILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDPIG 612

  Fly   425 AREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLR 489
            |.:...:   .::.|::|..|.:||..|||||:.:..:......:.|.|.          :..|.
Mouse   613 ASQKTFI---SHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVA----------VSELS 664

  Fly   490 SNIAVVGQEPVLFQGSIGENIRHGKPEATQ--KEVEDAAKAANAHDFIIALHKGYDTDISEKGVQ 552
            ....:..|||.:...:|.:||..||....|  :||.:|. |.|  |.:..|..|..|::.||||.
Mouse   665 KGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEAC-ALN--DDLSILPAGDQTEVGEKGVT 726

  Fly   553 LSGGQRQRIAIARALIQQPKILLLDEATSALDYH-SEKLVQAALDKACKGRTTLVVSHRLSAIRH 616
            ||||||.|||:|||:.|:..:.|||:..:|:|.. :..|:...:.......|.|:.:||...:..
Mouse   727 LSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTRLLCTHRTEYLER 791

  Fly   617 AHRIVYIENGKAVEQGTHEELMKLEGFYHKMVTVHSYDDSAEELLNELEEVAEIKERKMSYEVEP 681
            |..::.:|.|:.|..|...|::.|.             .:......|.|:||
Mouse   792 ADVVLLMEAGQLVRTGPPSEILPLV-------------QAVPTAWAEKEQVA------------- 830

  Fly   682 YQLGTRNSIVSLEKNAEFQMKNLNGLANITMNQEIDDPRVPSANFISTFFRILG----------- 735
             ..|...|:..||:..|.:::.........:.:|.......:.:....::|.:|
Mouse   831 -TSGQSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSL 894

  Fly   736 -----------WARPEW-SFLIIG--------AICA----GLYGVTMPVFSVVLAELYGS-LAKP 775
                       |....| |.|..|        |.|:    .|:...:.:||.  ..||.. |:.|
Mouse   895 LLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSP--GNLYTPLLSTP 957

  Fly   776 TDEEVLEQSASMAIISLVIGIAAGV--VC-YIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFD 837
            ..:.....:|.:....:|....|||  :| .::...|....:.....:..:....::...:.::|
Mouse   958 LHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYD 1022

  Fly   838 RKENSIGALSARLSGDAASVQGAIGFPLSNIIQA----FTNFICSIAIAFPYSWELALICLSTSP 898
            ...:  |.:..|.|.|.|.|..::.| |.||:.|    ....:..:....|:    .|:.|....
Mouse  1023 STPS--GRVLNRFSSDVACVDDSLPF-LLNILLANSVGLLGLLAVLGSGLPW----LLLLLPPLS 1080

  Fly   899 FMVASI--VFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGL----------RREEELIKI 951
            |:..|:  .:.|.|.|...|.........|.:|.       |:|||          |.|||..::
Mouse  1081 FVYYSVQGYYRASFRELRRLGSLTWSPLYSHLAD-------TLAGLPVLRAAGATYRFEEENQRL 1138

  Fly   952 YDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKISNTMLYG 1016
            .:.. :|.:....:.::|      |...|...|.||.....|......:      ..::|..|.|
Mouse  1139 LELN-QRCQFASYATMQW------LDIRLQLMGAAVVSAIAGIALVQHQ------QGLANPGLVG 1190

  Fly  1017 LFILAQSLAFTPAFN----------AALLSANRMYEIIDRKPQ------IQSPESFEIQQNGNGT 1065
            | :|:.:|:.|...:          |.::|..|:.|.....||      :|||....|.....|:
Mouse  1191 L-VLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGS 1254

  Fly  1066 AYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDP 1130
            ....:||   :.||      |..|:  .|......:..|:.:.:||.:|||||:...:|.|..:|
Mouse  1255 VEFQDVV---LVYR------PGLPN--ALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEP 1308

  Fly  1131 DEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMA- 1194
            :.|::|:|.... ..::|..||.:|.::.|||.||..:|.:|:..........:.|.:|...::
Mouse  1309 NAGRVLLDNVDT-SQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSE 1372

  Fly  1195 -------------------NAH-EFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKIL 1239
                               |.| :....|....|..||.:|..||.||:|.:.:|||::.:.|||
Mouse  1373 VAVAMGESQACQRSQREAKNGHWQCSALLTGGLDGELGERGQNLSLGQRQLLCLARALLTDAKIL 1437

  Fly  1240 LLDEATSALDFQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQL 1302
            .:||||:::|.::::::||.:....:.:|.:.|||||:||.|::.:.|:|||::||..|.|.|
Mouse  1438 CIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSAL 1500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	302/1368 (22%)
		ABC_membrane	<147..333	CDD:279056	37/197 (19%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	68/240 (28%)
		ABC_membrane	749..1019	CDD:279056	58/293 (20%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	75/248 (30%)
Abcc10	NP_001334325.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000