Protein Alignment CG10226 and haf-8

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_502776.1
• Gene: haf-8 / 190369
• WormBaseID: WBGene00001818
• Length: 633
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 205/573 - (35%)
• Similarity: 305/573 - (53%)
• Gaps: 68/573 - (11%)

  Fly   103 GKILTNASYEENMQELRKDSVSFGILMTLNTLLMLF--------SGVYYVDAFNRLALKLTVR-M 158
            |:::|||...:          ||.|:.....||.|.        |..|:   |.:.|.|||.| :
 Worm    79 GQMMTNAIQMK----------SFDIIKRACLLLALIQFSEATCKSACYF---FMQYAEKLTARNI 130

  Fly   159 RREFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGW 223
            |.:.|::.|.|||.:.|..|......|||.:.|.|.:.:..::...|..:.....|:.:.|.|.|
 Worm   131 RIQLFRSILHQEISFFDENKTGQLVSRITHDSESISNTLPVHIETLVNNLFMFFGSIPIMFCYSW 195

  Fly   224 KLALAIVFYIPLTLVVNSAVAHYQG----KLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSE 284
            :|.|......|:||:    :..|.|    ||:.:|..:...::..||||:.|||||.:|..|..|
 Worm   196 QLTLTSFIEFPITLL----MTRYYGLAVEKLSEKENDATAASNETVEEVLSAIRTVRSFAAENFE 256

  Fly   285 SLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFW----YGANLILYYRDPSIPIDER 345
            ..||..      ....|   |...:.||....::    ..||    ...::|.|.....:.::.|
 Worm   257 QKRYTK------NTEDW---FKISTKTVTLGTIY----NYFWALMLRSQDVIRYLYGGYLALNGR 308

  Fly   346 EYTPAVVMIVIS--GIIVSANQISRT-SPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILN 407
            ....|::..:..  .:..:.|..|.. |..::|..::|    .::.:|:|...:|        .:
 Worm   309 MAPEALLTFIFYHWRLHTAINAFSSLFSGVMKTIGLSR----KVIHLINRKPQLD--------YD 361

  Fly   408 YG-----LKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYD 467
            :|     ::|.:||..|.|.||.|:.|.|:.|:|:.:|.|:|||||||||.||||.:.|:|:||.
 Worm   362 FGTETPEIQGKIEFEVVEFAYPTRKTVNVINGINLSIESGKTVALVGPSGNGKSTLVSLIQQFYT 426

  Fly   468 PVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAH 532
            |..|::|.||..::..|.:...||||:|.|||.||.|:|.|||..|....|::.:..||:.||.|
 Worm   427 PQSGRILTDGIPIQNINHQHYHSNIALVAQEPTLFSGTIRENILFGIENGTEEAMLKAAEMANVH 491

  Fly   533 DFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDK 597
            :|:..:..||||...|||||:||||:||||||||||:.|::|:|||||||||..||.:||.||:|
 Worm   492 EFVSKMDDGYDTKCGEKGVQMSGGQKQRIAIARALIRNPRVLILDEATSALDSESEGMVQEALNK 556

  Fly   598 ACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMK-LEGFYHKMVT 649
            ..|.||.:|::||||.:|.|.:|..||||...|.|.|:|||: .:|.|:|:|:
 Worm   557 CAKERTVIVIAHRLSTVRKAQKIAVIENGSVKEMGCHDELMENQDGLYYKLVS 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	205/573 (36%)
		ABC_membrane	<147..333	CDD:279056	54/194 (28%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	124/235 (53%)
		ABC_membrane	749..1019	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216
haf-8	NP_502776.1	MdlB	42..613	CDD:224055	205/573 (36%)
		ABC_membrane	63..318	CDD:279056	70/268 (26%)
		ABC_MTABC3_MDL1_MDL2	373..611	CDD:213216	125/237 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910