Protein Alignment CG10226 and pgp-13

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_001359545.1
• Gene: pgp-13 / 184845
• WormBaseID: WBGene00004007
• Length: 1323
• Species: Caenorhabditis elegans
• Alignment Length: 1344
• Identity: 457/1344 - (34%)
• Similarity: 702/1344 - (52%)
• Gaps: 152/1344 - (11%)

  Fly    33 QPMVSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVVYSEL--VAMFIERTLGQGTSSVTI 95
            || ||..:|||:...:||::||.|.:.:.:..:..|:..::...:  |.:.|:....:..:....
 Worm    74 QP-VSLLQLFRFATTFDYILLLIGLITSVISGVSQPVLAIISGRMTNVLLVIDPLSKEFKTKTME 137

  Fly    96 GLSLFGGGKILTNASYEENMQELRKDSVSFGILMTLNTLLMLFSGVYYVDAFNRLALKLTVRMRR 160
            .:.:|.|                      .||.:::|......       .|.|:..::...||.
 Worm   138 NVYIFLG----------------------LGIFVSINDFCQYM-------CFQRVCSRMMTVMRN 173

  Fly   161 EFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKL 225
            .:..:.|||..||.|.........|:.||||:|:.|:.:.||..:..:..||.|||:|.||.|:|
 Worm   174 RYISSILRQNAGWFDKNLSGTITTRLNDNMERIQDGVGDKLGVLIRGISMVIASVVISLIYEWRL 238

  Fly   226 ALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDS 290
            ||.::..||::.:..:.::.:..|.||:|......|.::.||.:..:||:.||.|:.....:|:.
 Worm   239 ALMMLGLIPVSTICMTLLSRFLEKSTGEELEKVGEAGAIAEECLMGVRTIQAFNGQEEMVAKYEK 303

  Fly   291 LLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFW----------YGANLILYYRDPSIPIDER 345
            .|....|...|.|.:||          |..|...||          ||..|:      .:.|.:
 Worm   304 QLNSGKKHAIWGGFWSG----------FFGGIFFFWLMAFMGCGILYGGYLL------KVGIIK- 351

  Fly   346 EYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILNYGL 410
              :|..|.|::..:::.|..:...||.|.....||.:|::|...|||...|||.|:.||.:. .:
 Worm   352 --SPGDVFIIVVAMLLGAYFLGLISPHLMVLLNARVAAASIYKTIDRVPKIDPYSRHGKKIE-KV 413

  Fly   411 KGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLL 475
            .|.|.|.:|.||||.|::..||.|||:.||.|.:|||||.|||||||.:.||.|.|:|..|.|.:
 Worm   414 VGKVTFENVHFRYPTRKEAKVLNGLNLTVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEQGSVQI 478

  Fly   476 DGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAHDFIIALHK 540
            ||.|||..|::|||:.:.:|.|||:||..:|..|:..|.|:||::.:....|.|||||||..:.|
 Worm   479 DGVDVRDLNLEWLRNVVGIVQQEPILFNDTIHNNLLFGNPDATRETMIRVCKMANAHDFIKKMPK 543

  Fly   541 GYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDKACKGRTTL 605
            ||||.|.:.||||||||:||:||||.||:.||:|||||||||||..||.:||:||:.|.|||||:
 Worm   544 GYDTQIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSALNNASKGRTTI 608

  Fly   606 VVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKLEGFYHKMVTVHSYDDSAEELLNELEEVAEI 670
            :::||||.||.|.:||:.|.|..||.|.||||:.|.|.|..:|...::....:|:..|.||..:.
 Worm   609 MIAHRLSTIREADKIVFFEKGVIVEAGNHEELVNLGGRYFDLVKAQAFKQDPDEIALEKEEEDQF 673

  Fly   671 KE--------RKMSYEVEPYQLGTRNSIVSLEKNA-EFQMKNLNGLANITMNQEIDDPRVPSA-- 724
            .|        ||:|         .|||..|....: ||:.   ..|||.:.::......:|||
 Worm   674 DEFDKPTVFNRKVS---------VRNSRSSGRSGSEEFRR---GSLANHSFDRFRKASHIPSAED 726

  Fly   725 ---------------NFISTFFRILGWARPEWSFLIIGAICAGLYGVTMPVFSVVLAELY-GSLA 773
                           ...:.|..|...|:..:::::||...|.:.|:.:|.|:::.|.:: |...
 Worm   727 EAFALRVKETMEKDGEITAGFLDIFKNAQGNYTYMLIGLSAALIRGLDLPTFALLFAWVFEGFEF 791

  Fly   774 KPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDR 838
            .|...:::.:.|...|.....|:.......:.|..|.:....|..|.|...||.::.|:..:||.
 Worm   792 VPYGGKMMHRLAMSVIAHCAAGLGIWFFQTLSTVMFAIVSENLGVRFRVAAFRNLLYQDAAYFDN 856

  Fly   839 KENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTS-----P 898
            ..::.|:|..||:.|...|:..:...:..::.|....|..:.|.|...|::|:  |.|:     .
 Worm   857 PAHAPGSLITRLAADPPCVKAVVDGRMMQVVYATAAVIACVTIGFINCWQVAI--LGTALIFLLG 919

  Fly   899 FMVASIVFEARFGEKSALKEKEVLE--ETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRH 961
            |::|.:.|      |.::...|.:|  :..:||.|.|..::|:..|.|....:..|:.|.::.:.
 Worm   920 FIMAGLAF------KISIVAAEHMENDDAGKIAIEIIENVKTIQLLTRTRRFLNSYENESKKRKR 978

  Fly   962 QILSRLKWRGLVNSLGKSLMF------FGYAVTLTYGGHMCADGKIKFETIMKISNTML--YGLF 1018
            ..|.:..:..:...:.::.|:      |..|:.:...|....|     :|...:...||  .|:.
 Worm   979 TELRKSVYEAVNYCISQNFMYYMSCFCFALAIRIINQGDQTVD-----KTFRCLMAMMLCCEGII 1038

  Fly  1019 ILAQSLAFTPAFNAALLSANRMYEIIDRKPQ---IQSPESFEIQQNGNGTAYKTNVVQQGVSYRG 1080
            :.||   |.|.|..|..:|.:|:.:|:|:||   ::|....||:.|              :.:..
 Worm  1039 MSAQ---FFPQFVGAKSAAGQMFNLINRQPQTGDLKSGTKPEIRGN--------------ILFEN 1086

  Fly  1081 LNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHHD 1145
            :.||||.|||..|::.......:||||||||.||||||||:.:|.|:||...|.:.:|.:.| .:
 Worm  1087 VKFSYPQRPHQPVMKQLQWTALRGQTVALVGPSGSGKSTCIGMLERFYDVTGGALRMDGQDI-KN 1150

  Fly  1146 MDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTV 1210
            :.|..||.::.:|.|||.||..:|.:|:..|  .:.||:::|.:|.::|||:.|:.:||...||.
 Worm  1151 ISLYHLRTQMALVGQEPRLFVGTIRENVCLG--LKDVPLEKINQALELANANRFLGNLPDGIDTE 1213

  Fly  1211 LGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSGRTCIVIAHR 1275
            :|.:|.|||||||||||||||:||:||||||||||||||.:|||.||:|||.|..|||||.||||
 Worm  1214 VGERGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEALDRAREGRTCITIAHR 1278

  Fly  1276 LSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYRCQTKA 1319
            ||:|||:::|..|..|::.|.|:|.:|:...|.|.:|.:.|..|
 Worm  1279 LSSIQNSDLIVYIDDGRVQESGTHKELMQLKGKYFELIKKQDLA 1322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	440/1284 (34%)
		ABC_membrane	<147..333	CDD:279056	59/195 (30%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	132/234 (56%)
		ABC_membrane	749..1019	CDD:279056	59/285 (21%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	121/239 (51%)
pgp-13	NP_001359545.1	PTZ00265	92..1317	CDD:240339	446/1318 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63700
OrthoDB	1	1.010	-	-		D186078at2759
OrthoFinder	1	1.000	-	-		FOG0000106
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X92
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790