Protein Alignment CG10226 and pgp-14

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_510128.1
• Gene: pgp-14 / 181416
• WormBaseID: WBGene00004008
• Length: 1327
• Species: Caenorhabditis elegans
• Alignment Length: 1370
• Identity: 481/1370 - (35%)
• Similarity: 728/1370 - (53%)
• Gaps: 146/1370 - (10%)

  Fly     9 DVPA---ADADEA----TPAAQKK-----------KKTKEKAQPMVSYTELFRYIAGWDYLVLLS 55
            |:||   .|.|:|    ||:..:|           ...:.:||| ||...||||...:|||:|..
 Worm    44 DLPANYVDDDDDAPKMYTPSLLEKILNYALCRGDIANQQLEAQP-VSIPGLFRYGKKFDYLLLFI 107

  Fly    56 GFVAAFLQSLVFPIAIVVYSELVAMFIERTLGQGTSSVTIGLSLFGGGKILTNA--SYEENMQEL 118
            |.:.|.:..:..||..:|                            .|:: |||  .|....::.
 Worm   108 GTICAIISGVSQPILALV----------------------------SGRV-TNALLVYPPTSKQF 143

  Fly   119 R-KDSVSFGILMTLNTLLMLFSGVYYVDAFNRLALKLTVRMRREFFKATLRQEIGWHDMAKDQNF 182
            | |.:.:..|.:.:...:.:.:.:.|: .|.....::..:||..|..:.|||..||.|.......
 Worm   144 RNKANENVYIFLGIGIFISITNFIQYM-CFQHCCTRVMAQMRHRFVYSVLRQNAGWFDKNHSGTI 207

  Fly   183 AVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQ 247
            ..::.|:||:||.||.:.||..:.....:|.::|:::||.|:||..::...|...:..|.:|...
 Worm   208 TTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVAYIYEWRLASMMLGVAPTCCICMSLLARQM 272

  Fly   248 GKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTV 312
            ...|.:|.....:|.|:.||.:..:|||.||.|:.....||::.|:...|...|||.:||
 Worm   273 TSTTIKELIGVGKAGSIAEESLMGVRTVQAFNGQEEMVGRYEAELEKGRKFAVWKGFWSG----- 332

  Fly   313 MKAMLFITGAGSFW----------YGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQIS 367
                 |..|...||          |||.|:      .:.|..   ||..|.||:..:::.|..:.
 Worm   333 -----FFGGLFFFWLFSFLGCGMLYGAYLL------KVGIIT---TPGDVFIVVMSMLLGAYFLG 383

  Fly   368 RTSPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVL 432
            ..||.:.....||.||::|...|||...|||.|||||.|. .:.|.|:|.:|.||||:|:|..:|
 Worm   384 LISPHMMVLLNARVSAASIYQTIDRVPKIDPYSKAGKRLQ-NVVGRVKFENVHFRYPSRKDAKIL 447

  Fly   433 RGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQ 497
            .|||:|||.|.:|||||.|||||||.:.||.|.|:|..|.|.:||.|||:.||:|||:.:.:|.|
 Worm   448 NGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVTIDGTDVRELNIEWLRNTVGIVQQ 512

  Fly   498 EPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIA 562
            ||:||..:|..|:..|.|.:|::.:.:..|.|||||||..:.|||||.|.:.||||||||:||:|
 Worm   513 EPILFNDTIHNNLLIGNPGSTRETMIEVCKMANAHDFIEKMPKGYDTLIGDGGVQLSGGQKQRVA 577

  Fly   563 IARALIQQPKILLLDEATSALDYHSEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGK 627
            |||.||:.||:|||||||||||..||.:||:||:.|.|||||::::||||.||.|.:||:.|.|.
 Worm   578 IARTLIRDPKVLLLDEATSALDAQSESIVQSALNNASKGRTTIMIAHRLSTIREADKIVFFEKGV 642

  Fly   628 AVEQGTHEELMKLEGFYHKMVTVHSY--DDSAEELLNE----LEEVAEIKERKMSYEV----EPY 682
            .||.|.||||::|.|.|..:|....:  |..|.|...|    |::.:....|......    |.:
 Worm   643 IVEAGNHEELVRLGGRYFDLVKAQQFKADPEATEEFEEEEIDLDDTSRSSRRSSMTSARSGSEAF 707

  Fly   683 QLGT--RNSIVSLEKNAEFQMKNLNGLANITMNQEIDDPRVPSANFISTFFRILGWARPEWSFLI 745
            :.|.  .:|....:::|:...:|....||..... .:|.:: :|.::..|..    |:..:.::.
 Worm   708 RRGNSLNDSFSGSKRSAQADAENSAFAANEAAIM-AEDGQI-TAGYLDIFKN----AKGNYLYMF 766

  Fly   746 IGAICAGLYGVTMPVFSVVLAELY-GSLAKPTDEEVLEQSASMAIISLV-IGIAAGVVCYIQTFF 808
            :|.:.|.:.|:.:|..:::...:: |....|....::.:.| ||:|:.. :|:.........:..
 Worm   767 LGTVFALIRGLELPALALIFGWVFEGFTFVPYGGRMMHRMA-MAVIAFASVGVGVWFSQLASSVL 830

  Fly   809 FNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFT 873
            |.:....|:.|.|.::||.::.|:..:||...::.|.|..||:.||.:::..:...:..:|.|..
 Worm   831 FAVVSENLSMRFRVQSFRNLLYQDASYFDNPAHAPGKLITRLASDAPNIKAVVDARMLQVIYALA 895

  Fly   874 NFICSIAIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVL-EETSRIATETITQIR 937
            ..|.:|||||.|.|::.:  |.||..::.:.|......:.|.:..:::. ::..|||.|.|..::
 Worm   896 AIIANIAIAFIYCWQIGI--LGTSLILLLAFVMIGLAYKISLMNVEQIQNDDAGRIAIEIIENVK 958

  Fly   938 TVAGLRREEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSL--------MFFGYAV--TLTYG 992
            |:..|.|.|   ..:|......:.|..|.|| :|::.::..||        |.|.|||  .:.|.
 Worm   959 TIQLLTRCE---LFFDHYQTSSKQQKRSELK-KGMIEAINYSLTQSFMYFMMCFTYAVGIRIIYQ 1019

  Fly   993 GHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQ---IQSPE 1054
            |...:|.  .|:.|:    .|:.|...:..|..:.|.|..|..:|..::.||.|||:   :...:
 Worm  1020 GDKSSDD--TFKGII----AMMLGAVAVMNSAQYFPEFVKAKTAAGMLFNIIYRKPRTGDLMEGD 1078

  Fly  1055 SFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKST 1119
            ..||:.|              :.:..:.||||.||...:::.......:||||||||.|||||||
 Worm  1079 RPEIRGN--------------ILFENVKFSYPQRPLQPIMKGLQWTALRGQTVALVGPSGSGKST 1129

  Fly  1120 CVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPM 1184
            .:.:|.|:||...|.:.||.:.| ..:.|..||.::.:|.|||.||..:|.:|:..|  .:.||:
 Worm  1130 NIGMLERFYDVTGGALRIDGQDI-RKLSLFHLRTQMALVGQEPRLFAGTIRENVCLG--LKDVPL 1191

  Fly  1185 QQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALD 1249
            ::|.:|.::|||:.|:.:|||..||.:|.||.|||||||||||||||:||:||||||||||||||
 Worm  1192 EKINQALELANANRFLANLPAGIDTDVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALD 1256

  Fly  1250 FQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYR 1314
            .:|||.||:|||.|..|||||.||||||:|||:::|..|..||:.|.|:|:||:.:.|.|.||.:
 Worm  1257 SESERAVQEALDRAREGRTCITIAHRLSSIQNSDLIVYIDKGKVQEAGNHTQLMHQKGRYYKLIK 1321

  Fly  1315 CQTKA 1319
            .|..|
 Worm  1322 KQDLA 1326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	450/1270 (35%)
		ABC_membrane	<147..333	CDD:279056	58/195 (30%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	133/234 (57%)
		ABC_membrane	749..1019	CDD:279056	69/282 (24%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	124/239 (52%)
pgp-14	NP_510128.1	PTZ00265	104..1321	CDD:240339	458/1302 (35%)
		ABC_membrane	109..377	CDD:279056	77/316 (24%)
		ABC_MTABC3_MDL1_MDL2	429..666	CDD:213216	134/236 (57%)
		ABC_membrane	769..1039	CDD:294371	69/282 (24%)
		ABC_MTABC3_MDL1_MDL2	1086..1323	CDD:213216	124/239 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63700
OrthoDB	1	1.010	-	-		D186078at2759
OrthoFinder	1	1.000	-	-		FOG0000106
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X92
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.790