Protein Alignment CG10226 and hmt-1

DIOPT Version :10

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_001022812.1
• Gene: hmt-1 / 176540
• WormBaseID: WBGene00001815
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 169/599 - (28%)
• Similarity: 295/599 - (49%)
• Gaps: 73/599 - (12%)

  Fly   744 LIIGAICAGLYGVTMPVFSVVLAELYGSLAKPTDEEVLEQSASMAIISLVI------GIAAGVVC 802
            ||||.    |..|::|:.|..:.:   .||.|...:.     |:..::..:      |...|.:.
 Worm   234 LIIGR----LINVSLPILSKWIVD---ELATPDTFQY-----SLLFLATFLKFLQGNGAMGGFLN 286

  Fly   803 YIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGW-FDRKENSIGALSARLSGDAASVQGAIGFPLS 866
            .::|:.:.....:.|..:..:.|:.:.:..:.| ..||...:..:..|   ..:||...:.:.|.
 Worm   287 TVRTYLWIPIQQYTTRELEVELFKHLHSLSLRWHLSRKTGQVLRVMDR---GTSSVNNILNYILF 348

  Fly   867 NIIQAFTNFICSIAIAF-PYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIAT 930
            |::....:.:.::...| .::....||...|....:...:....:..:...:..|....||.|||
 Worm   349 NVVPTIADIVIAVIFFFSAFNAYFGLIVFGTMALYLTVTISITEWRTQYIREANEKDNATSAIAT 413

  Fly   931 ETITQIRTVAGLRREEELIKIYDKEVERYRHQILSR--LKWR-----GLVNSLGKSLMFFGYAVT 988
            :::....||.....||       .||.|:::.|.|.  .:|:     ..:|.|..:::..|
 Worm   414 DSLINYETVKYYGNEE-------FEVNRFKNAIESYQVTEWKTQASLAFLNCLQNAIIGIG---- 467

  Fly   989 LTYGGHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTP---------AFNAALLSANRMYEII 1044
             ..||.:.....|..|..:.:.:.:|:..::|.   .:||         ....|.:....|::::
 Worm   468 -MIGGSVFVVYMIVHEKTLTVGDYVLFTTYLLQ---LYTPLNFFGTIYRVIQKAFVDMENMFDLM 528

  Fly  1045 DRKPQIQSPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVAL 1109
            :.:.:::.........:..||          :|.:.|.|.|  ...:.|::|.:.:|..||||||
 Worm   529 NDEVEVKDLPHALPYTDPRGT----------ISVKNLTFEY--NTGLPVIKNISFEIGNGQTVAL 581

  Fly  1110 VGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIG 1174
            ||:|||||||.::||.|.::..||.|..|...: .:..:.:||:::|||.|:..||..:|..||.
 Worm   582 VGSSGSGKSTLIRLLFRLFESTEGSIEFDGIDV-RNYTMHSLRQQIGIVPQDTVLFNDTIMYNIR 645

  Fly  1175 YG--DTSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPK 1237
            :|  |.|.    :::|||||.|..||.|.|||..|.|::|.:|.:||||:|||:||||.:::.|:
 Worm   646 FGRPDASD----EEVIEAAKAAMIHEKITSLPEGYATMVGERGLKLSGGEKQRVAIARTILKKPQ 706

  Fly  1238 ILLLDEATSALDFQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQL 1302
            .:.|||||||||..:||.:|:.|:..|..||.:|:||||||:.||::|.|:..|.|:|:|:|.:|
 Worm   707 FIFLDEATSALDTPTERAIQKCLEKLCKSRTGVVVAHRLSTVVNADLILVLDKGIILERGNHKEL 771

  Fly  1303 LAKNGIYSKLYRCQ 1316
            ||:.|.|:.::..|
 Worm   772 LAQQGTYASMWEAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	MdlB	147..652	CDD:440747
		MdlB	723..1320	CDD:440747	169/599 (28%)
hmt-1	NP_001022812.1	ATM1	213..791	CDD:444078	169/599 (28%)