Protein Alignment CG10226 and LOC100494753

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_017951387.2
• Gene: LOC100494753 / 100494753
• -ID: -
• Length: 1319
• Species: Xenopus tropicalis
• Alignment Length: 1350
• Identity: 530/1350 - (39%)
• Similarity: 787/1350 - (58%)
• Gaps: 98/1350 - (7%)

  Fly     9 DVPAADADEATPA---AQKKKKTKEKAQP--MVSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFP 68
            |.||...||....   .:||||.|:.:.|  ||.:.|||.:...||.::::.|.|.........|
 Frog    23 DNPAFQEDEPPEKYGFFKKKKKEKKDSAPVAMVGFLELFSFADSWDIMLMIIGIVCGLAAGTGLP 87

  Fly    69 IAIVVYSELVAMFIERTL----GQGTSSVTIGLSLFGGGKILTNASYEENMQELRKDSVSFGILM 129
            |.|:|:..:...|::..:    .|.||:.:.....||      ....|..|.:.....|:.|..:
 Frog    88 IMIIVFGTMTDSFVQSGIPVNYTQNTSTTSTSCGHFG------TMDIEAEMTKYAYYYVAIGCSI 146

  Fly   130 TLNTLLMLFSGVYYVDAFNRLALKLTVRMRREFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIR 194
            .:.:|..:::       |...|.:.|.|:||.||||.|.||:.|.|..:......|:|:::..|.
 Frog   147 FVLSLFQVWT-------FLVSASRQTTRIRRMFFKAVLHQEMSWFDATQIGTLNTRLTEDINTIH 204

  Fly   195 SGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAV-AHYQGKLTGQEQSSY 258
            .|:.:.:..:::.....|..:::.|::||||.|.|:...|| |..::|| .......|.:|.::|
 Frog   205 EGLGDKISIFLQFFSTFISGIIIGFVHGWKLTLVIMSVSPL-LGASAAVWTKLLANFTSKELNAY 268

  Fly   259 VRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAG 323
            .:|.:|.|||:.||||||||.|::....:||..|:.|.|.|..|...:.||..:.:.::|...|.
 Frog   269 GKAGAVAEEVLTAIRTVVAFNGQKKALKQYDKHLENAKKVGIRKSITTNLSMGIAQFLIFGAYAL 333

  Fly   324 SFWYGANLILYYRDPSIPIDERE-YTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAIL 387
            .||||..|         .:||.: ||...|:||...:::....:.:.:|.||:.|.|||:|..:.
 Frog   334 GFWYGTKL---------TVDEPDTYTIGKVLIVFFSVLIGTFSLGQAAPNLESIASARGAAFEVY 389

  Fly   388 DVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSG 452
            .:|.:..|||..|..|...: .|.|.:||:::.|.||:|.|:.:|:|||:.||.|:|:||||.||
 Frog   390 KIIKQPRLIDSSSTEGHKPD-RLMGNIEFKNIHFSYPSRPDIQILKGLNLNVETGKTIALVGASG 453

  Fly   453 CGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEA 517
            |||||.||||||||||..|::.:||.|:|..|:||||.||.||.||||||..:|.|||::|:.:.
 Frog   454 CGKSTTIQLLQRFYDPPKGEITVDGHDIRTLNVKWLRENIGVVSQEPVLFGATIKENIQYGREDV 518

  Fly   518 TQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSA 582
            |..|:|.|:|.|||:|||..|...::|.:.|:|.||||||:|||||||||::.||||||||||||
 Frog   519 TDAEIEQASKEANAYDFIQKLPDKFETMVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSA 583

  Fly   583 LDYHSEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKLEGFYHKM 647
            ||..||.:||:|||||..||||:|::||||.||.|..|....||..||||.|.|||..:|.|:.:
 Frog   584 LDTQSEAIVQSALDKARAGRTTIVIAHRLSTIRTADVIAGFHNGVVVEQGNHNELMNQKGVYYSL 648

  Fly   648 VTV-----HSYDDSAEELLNELEEVAEIKERKMS--YE---VEPYQLGTRNSIVSLEKNAEFQMK 702
            |.:     |..:||::   :|.||.:...|....  ||   ||.|..|:.|    :.:| :||.|
 Frog   649 VMLQSHGKHKEEDSSQ---SEGEESSNSDEENEGNVYENEIVEDYNNGSEN----ISRN-DFQRK 705

  Fly   703 -------------NLNGLANITMNQEIDDPRVPSANFISTFF--RILGWARPEWSFLIIGAICAG 752
                         :.:..|....|:..:|        :.||.  ::|...:|||.:::||.|.:.
 Frog   706 SSRRKSKRKSKKSSKSKKATDNTNKVEED--------LPTFSLGKVLAMNKPEWYYIVIGVIASA 762

  Fly   753 LYGVTMPVFSVVLAELYGSLAKPTDEEVLEQSASMAIISLVIGIAAG---VVCYIQTFFFNLAGV 814
            :.|...|.|:|:..::.||. :.||.:  ::||...::||:..:..|   :|..|..|.|.::|.
 Frog   763 INGGIYPTFAVIFGKIIGSF-QITDPD--KRSAETVLLSLMFLVLGGLSLIVYIILGFAFGISGE 824

  Fly   815 WLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSI 879
            .||.|:||..|:.::.||:|:||...|::|.|..||:.||:.|:||.|..:..|..:....:.:|
 Frog   825 NLTMRLRSLCFKALIRQEIGYFDDHANAVGVLLTRLATDASQVKGATGSRIGLITLSVCTLLAAI 889

  Fly   880 AIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRR 944
            .|||.|.|:|.|:.|:..||::.:.....:.....|.|:::.||:..:|:||.:..||||..|.|
 Frog   890 IIAFVYGWQLTLLILACVPFLIGANFIRMKSMAGHASKDQKALEQAGKISTEAVGNIRTVVSLTR 954

  Fly   945 EEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKI 1009
            ||...:.|::.:.....:.:.:....|...::.:.:.||..|....:|..:.|...::||.:..:
 Frog   955 EERFYERYNESLSVPYKETIVKAPLYGFTYAISQCMNFFVNAAVFRFGAWLIAHCYLQFENVFIV 1019

  Fly  1010 SNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQSPESFEIQQNGNGTAYKTNVVQQ 1074
            .:.:::....:.||.:..|.|..|.:||.|:.::::|||||.|     ..::|:    |.:....
 Frog  1020 FSAIIFAAMNVGQSTSLAPDFGKARVSAQRIMKLLERKPQIDS-----YSEDGD----KLSSFDG 1075

  Fly  1075 GVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKIL--- 1136
            .:.:|.:.|.||:||.::|||..|:.:::|||:||||:||.||||.||||.|:|||.||::.
 Frog  1076 NLEFRNVKFVYPTRPKVQVLQGLNVKVSKGQTLALVGSSGCGKSTSVQLLERFYDPMEGQVFADG 1140

  Fly  1137 IDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIM 1201
            ||.:.    ::::.||.:||||||||.||:.|||:||.||...|||..::|.||||.||.|.||.
 Frog  1141 IDTKL----LNIQWLRSQLGIVSQEPILFDCSIAENIQYGFLERQVTQEEIEEAAKAANIHSFIE 1201

  Fly  1202 SLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSG 1266
            .||.:|:|.:|.||.|||||||||||||||::|.||:|||||||||||.:||:|||.|||:|..|
 Frog  1202 GLPNKYNTRVGDKGAQLSGGQKQRIAIARALIRKPKVLLLDEATSALDTESEKVVQNALDNARQG 1266

  Fly  1267 RTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYRCQ 1316
            |||:||||||:|||||::|.|||.|.::|||:|.|||||.|.|..|...|
 Frog  1267 RTCVVIAHRLTTIQNADIIAVIQNGIVIEQGTHGQLLAKQGAYYALVNSQ 1316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	504/1266 (40%)
		ABC_membrane	<147..333	CDD:279056	65/186 (35%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	139/234 (59%)
		ABC_membrane	749..1019	CDD:279056	77/272 (28%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	144/242 (60%)
LOC100494753	XP_017951387.2	PTZ00265	71..1310	CDD:240339	509/1294 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7270
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63700
OrthoDB	1	1.010	-	-		D186078at2759
OrthoFinder	1	1.000	-	-		FOG0000106
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X92
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930