Protein Alignment CG10226 and abcb11.2

DIOPT Version :9

• Sequence 1: NP_648040.1
• Gene: CG10226 / 38725
• FlyBaseID: FBgn0035695
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_004917764.1
• Gene: abcb11.2 / 100489579
• XenbaseID: XB-GENE-988819
• Length: 1349
• Species: Xenopus tropicalis
• Alignment Length: 1366
• Identity: 509/1366 - (37%)
• Similarity: 797/1366 - (58%)
• Gaps: 122/1366 - (8%)

  Fly    14 DADEATPAAQKKKKTKEKAQP--MVSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVVYSE 76
            |.::...|:.||.::|:|.:.  .|.:.:|||:....:..::|.|.:||.:.....|..::|:..
 Frog    31 DLNQNGNASSKKDESKKKPEDSIRVGFFQLFRFATCSETTMMLFGSLAAIIHGAAQPCMLLVFGL 95

  Fly    77 LVAMFIERTLGQGTSSVTIGLSLFGGGKILTNASYEENMQELR---------------------K 120
            ::..|||                           |:..|||||                     |
 Frog    96 MIDTFIE---------------------------YDIEMQELRDPNKTCTNNTITWTNGSLVPDK 133

  Fly   121 DSVSF--GIL---MTLNTLLMLFSGV-------------YYVDAFNRLALKLTVRMRREFFKATL 167
            |:.:|  |:|   :.:......::|:             ::|.|    |.:...|:|:.:|:..:
 Frog   134 DNKTFSCGMLDIELEMTNFASYYAGIGCSVLILGYMQICFWVTA----AARQIQRIRKLYFRKVM 194

  Fly   168 RQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFY 232
            |.||||.|.........|::|::.||...||:.:|.:::.....:...:|.|:.||||.|.|:..
 Frog   195 RMEIGWFDCTSVGELNTRMSDDINKINDAIADQVGIFIQRFTTFLSGFLLGFVNGWKLTLIIIAV 259

  Fly   233 IPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALK 297
            .||..|..:.:|....||||:|..:|.:|.:|.:||:..||||.|||||..|..|||..|..|.:
 Frog   260 SPLIGVGAALMALAVAKLTGRELLAYAKAGAVADEVLSGIRTVAAFGGETKEVDRYDRNLVYAQR 324

  Fly   298 AGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVS 362
            .|..||...|.....|..::|:..|.:||||:.|:|         :|.||:|..::.|..|::|.
 Frog   325 WGIRKGIIMGFFTGYMWFIIFLCYALAFWYGSKLVL---------EEEEYSPGNLLQVFLGVLVG 380

  Fly   363 ANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPARE 427
            |..:.:.||.|:.||..||:|:.|.:.||....||.:|:.|..|: .:||.:||.::.|.||:|.
 Frog   381 ALNLGQASPCLQAFASGRGAATNIFETIDNEPKIDCMSEEGYKLD-KVKGEIEFHNISFHYPSRP 444

  Fly   428 DVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNI 492
            :|.:|..:|:|::.|:|.|.|||||.||||.:||:||||||..|.|.|||.|:|..||:||||.|
 Frog   445 EVKILDKINMVIKSGETTAFVGPSGAGKSTTVQLIQRFYDPDVGMVTLDGHDIRSLNIQWLRSLI 509

  Fly   493 AVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQ 557
            .:|.||||||..:|.||||:||..||.:|:..|||.|||::||:.|.:.:||.:.|.|.|:||||
 Frog   510 GIVEQEPVLFATTIAENIRYGKENATMEEIITAAKEANAYNFIMDLPQKFDTLVGEGGGQMSGGQ 574

  Fly   558 RQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVY 622
            :|||||||||::.|:|||||.||||||..||.:||.||||...||||:.::||||.|::|..||.
 Frog   575 KQRIAIARALVRNPRILLLDMATSALDNESEAIVQEALDKVRFGRTTISIAHRLSTIKNADVIVG 639

  Fly   623 IENGKAVEQGTHEELMKLEGFYHKMVTVHSYDDSAEELLNELEEV----AEIKERKMSYEVEPYQ 683
            .|:|:|||:|||:||::.:|.|..:||:.|..|.|   |:.:|:.    .|.:|.|:. .::|.:
 Frog   640 FEHGRAVEKGTHDELLERKGVYFTLVTLQSQGDKA---LHNMEKKDKSNKEFEEPKLE-TLQPLK 700

  Fly   684 LGTRNSIV--SLEKNAEFQMKNL-NGLANITMNQEIDDPRVPSA--------NFIST-------- 729
            .|:..:.:  |:.:.:..|:.|| .....:.:..:..||...|.        |.|.|
 Frog   701 RGSYQASLRASIRQRSRSQLSNLVPDTPLLVVGADASDPIQHSTHYDDESDNNMIKTEEIVEDIE 765

  Fly   730 ---FFRILGWARPEWSFLIIGAICAGLYGVTMPVFSVVLAELYGSLAKPTDEEVLEQSASMAIIS 791
               ..|||.:..|||.:::.|:|.|.:.|...|:::::.:::.|..:.|.:||..:|...:.::.
 Frog   766 PAPVARILKYNAPEWPYMLFGSIGAAINGAVSPLYALLFSQILGIFSLPDEEEQRDQINGICVLF 830

  Fly   792 LVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAAS 856
            ::||:.:.:..::|.:.|..:|..||.|:|...||.::.||:||||...||.|||:.||:.||:.
 Frog   831 VLIGVVSFLTQFLQGYTFAKSGELLTRRLRKLGFRSMLGQEVGWFDDPRNSPGALTTRLATDASQ 895

  Fly   857 VQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEV 921
            ||||.|..:..|:.|.:|...::.|||.:||:|.|:.:...||:..|...:|:.....|.::|..
 Frog   896 VQGATGSQIGMIVNAISNIGVALIIAFYFSWKLTLVIMCFLPFLAVSGALQAKMLTGFANQDKHA 960

  Fly   922 LEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYA 986
            :|...||::|.:..|||:||:.:|:..:.:|::::|......:.:....||.....:.::|....
 Frog   961 MESAGRISSEALGNIRTIAGIAKEKTFVDMYEEQLEAPYRSAIKKANVYGLCFGFAQCIVFIANT 1025

  Fly   987 VTLTYGGHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQ 1051
            |:..|||::.....:.:..:.::.::::.....|.::.::||.:..|.:||.|.::::||.|:|
 Frog  1026 VSYRYGGYLVDKEGLHYSFVFRVISSIVTSGTALGRASSYTPDYAKAKISAARFFKLVDRIPKI- 1089

  Fly  1052 SPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSG 1116
               |...........:|.:     :.::...|:||:||.|:||...::.:..|||:|.||:||.|
 Frog  1090 ---SVYTDHGERWPDFKGS-----IDFQDCKFTYPTRPDIQVLNGLDVSVKPGQTLAFVGSSGCG 1146

  Fly  1117 KSTCVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQ 1181
            |||.||||.|:||||:||:|||..: ..::::..||.::|||||||.||:.||.:||.|||.:::
 Frog  1147 KSTSVQLLERFYDPDKGKVLIDGHN-SKNVNVAFLRSKIGIVSQEPVLFDCSIIENIRYGDNNQE 1210

  Fly  1182 VPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATS 1246
            :...:||||:|.|..|:|:|.||.:|||.:|:.|:|||.|||||||||||:||:|||||||||||
 Frog  1211 LSKDKIIEASKKAQLHDFVMGLPDKYDTNVGAHGSQLSRGQKQRIAIARAIVRDPKILLLDEATS 1275

  Fly  1247 ALDFQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSK 1311
            |||.:||:.||.|||.|..||||||||||||||||:::|.|:..|.::|:|:|.:|:.|.|.|.|
 Frog  1276 ALDTESEKTVQAALDRAREGRTCIVIAHRLSTIQNSDIIAVMSRGIVIEKGNHEELMEKKGAYYK 1340

  Fly  1312 L 1312
            |
 Frog  1341 L 1341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10226	NP_648040.1	PTZ00265	81..1311	CDD:240339	491/1294 (38%)
		ABC_membrane	<147..333	CDD:279056	66/185 (36%)
		ABC_MTABC3_MDL1_MDL2	414..649	CDD:213216	132/234 (56%)
		ABC_membrane	749..1019	CDD:279056	75/269 (28%)
		ABC_MTABC3_MDL1_MDL2	1076..1316	CDD:213216	134/237 (57%)
abcb11.2	XP_004917764.1	PTZ00265	159..1340	CDD:240339	476/1208 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3127
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186078at2759
OrthoFinder	1	1.000	-	-		FOG0000106
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X92
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010