DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LanA and LAMA5

DIOPT Version :9

Sequence 1:	NP_476617.1	Gene:	LanA / 38723	FlyBaseID:	FBgn0002526	Length:	3712	Species:	Drosophila melanogaster
Sequence 2:	XP_006723859.1	Gene:	LAMA5 / 3911	HGNCID:	6485	Length:	3700	Species:	Homo sapiens

Alignment Length:	3974	Identity:	1263/3974 - (31%)
Similarity:	1877/3974 - (47%)	Gaps:	577/3974 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LVILAISYCQAE------LTPPYFNLATGRKIYATATCGQDTDG-------PELYCKLVGANTEH 63
            |.:|..:..:.|      |.|||||||.|.:|.|:||||::...       .:|||||||.....
Human    27 LALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAG 91

  Fly    64 DHIDYSVIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEVNLTINFEQEFHVA 128
            ...: ..|:||.||.|......:.||..|||||||.||||||||||:::||||:|::..|.||||
Human    92 GDPN-QTIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVA 155

  Fly   129 YLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPITRDDDVICTTEYS 193
            |:.|:..|||||.||.||:|.|:|:|:.|||.|:.:..||...||..|.:.|||||..|||||||
Human   156 YVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYS 220

  Fly   194 KIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGHLMSVARQDPTVTR 258
            :|||||||||.|.|:|.||.:.|:..|.:|:|:|:|||||:|.|||..||||||..|.:||||||
Human   221 RIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTR 285

  Fly   259 RYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNECCPGFEQKKWRQNT 323
            ||:||||||||||||:|:||||.||.|||..|.| |.|.|||:|||..|:.|||||.|:.|:..|
Human   286 RYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFNQQPWKPAT 349

  Fly   324 NARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTVGINCNKCKPKYYR 388
            ......|:.|||:||:.:|.||.||:|:..|..:.|.|.|||||.:|||:|.|:||.:|.|.:||
Human   350 ANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR 414

  Fly   389 PKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYYGYPNC-------- 445
            ......:...||..|.|:..|:.|.||:.||.|.||..|....||.||.|:.|:|:|
Human   415 SPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSN 479

  Fly   446 --RE----------CECNLNGTNGYHCEAESG-QQCPCKINFAGAYCKQCAEGYYGFPECKACEC 497
              ||          |:|:..||.|..|..:.. .:|.||.||.|.:|:.||.|:|| |.|:.|:|
Human   480 DTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG-PGCQPCQC 543

  Fly   498 NKIGSITNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQCIC 562
            :..|...:.|:..||:|:|...|.|..|:||..|||::|.|..|.|...||..|.|: ::|:|:|
Human   544 SSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCLC 607

  Fly   563 REGFGGPRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTLCTAGYYSYP 627
            :..|.||.||:|.||::.:|:|:.|.|...|:....|...|.|.|...:.|..|..|:.|::.:|
Human   608 QPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFP 672

  Fly   628 DCLPCHCDSHGSQGVSCN-SDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGV--IDKFA 689
            .|:||||.:.||...:|: ..|||.|:|...|.:||:|..|.||||.||..:|.|||:  :|...
Human   673 SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPAL 737

  Fly   690 GCGSVPVGELCKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKSGQCP 754
            ....||    |.|:..|.|..|:.|||.:|.|:.||.|||..|.|...||:..:..|...:|||.
Human   738 PEAQVP----CMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF 798

  Fly   755 CKPHTQGRRCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPL 819
            ||||..|:.|..|:||.|.||.|..|||:.|.||:||:....|:..:|.|:|.|...|..|::|.
Human   799 CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863

  Fly   820 TTHFFPTLHQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFKSSLY 884
            ..|:.|.||..:.|.|:.:.|.|..||:.::...|..||.:||.....:|..:...:|:....|:
Human   864 RDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNLTSPDLF 928

  Fly   885 RIVLRYVNPNAENVTATISVTSDNPLE-----VDQHVKVLLQPTSEPQFVTVAGPLGVKPSAIVL 944
            .:|.||||..|.:|:..:||..:....     ..|...|...|::||.|:||  |........||
Human   929 WLVFRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITV--PQRGFGEPFVL 991

  Fly   945 DPGRYVFTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPC-------ELGNMELCRHYKYASVE 1002
            :||.:....:| :.|:|||.||||:|||||.:|...::..|       :.|  :.|..|.:..::
Human   992 NPGTWALRVEA-EGVLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSG--DNCLLYTHLPLD 1053

  Fly  1003 VFSPAA--TPFVIGENSKPTNPVETYTDPEHLQIVSHVGDIPVLSGSQNELHYIVDVPRSGRYIF 1065
            .|..||  ......:||.|.........|.|..:::       .:||..::...|.||:.|||..
Human  1054 GFPSAAGLEALCRQDNSLPRPCPTEQLSPSHPPLIT-------CTGSDVDVQLQVAVPQPGRYAL 1111

  Fly  1066 VIDYISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICR-TSVNEDGMEKSFYINKEDLQPV 1129
            |::| ::.:......:.:........:..:.|:||||||:|| |:.:.......|:::.|  ..|
Human  1112 VVEY-ANEDARQEVGVAVHTPQRAPQQGLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSE--ASV 1173

  Fly  1130 IISADIEDGSRFPIISVTAIPVDQWSIDYINPSPVCVI-------HDQQCATPKFRSVP------ 1181
            .::|   :.:||.:..||.:|::::|.:::.|...|:.       :...|...:|...|
Human  1174 RLTA---EQARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILR 1235

  Fly  1182 DSKKIEFE-----TDHEDRIATNKP------PYASLDERVKLVHLDSQNEATIVIESKVDATKPN 1235
            |.:.|...     |..:|......|      |..::|...:...| .:.:||:|..:.|    |.
Human  1236 DCQVIPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTLL-REPQATVVFTTHV----PT 1295

  Fly  1236 L--FVILVKYYQPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRGVIRPAGEGSFEI-DDEF 1297
            |  :..|:..|||:||.:.|...:.||: .:.|..:...||...|||.::...|:...:: ..|.
Human  1296 LGRYAFLLHGYQPAHPTFPVEVLINAGR-VWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSEL 1359

  Fly  1298 KFTITTDRSQSVWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFHITHNASD-FCKKSV 1361
            ..|:...:.:.:||||::|||...|:...|.||..|::.:||.:|....:||:.::|. ||:.:.
Human  1360 TVTVRVPKGRWLWLDYVLVVPENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAA 1424

  Fly  1362 FSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFPDCKPCKCPNS 1426
            .||:..||:||.||.|...|:|...|.||||||.|..:||.|.|..|.:.|:|||:|:||.| .:
Human  1425 ASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDC-GA 1488

  Fly  1427 AMCEPTTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIAN-GNSQCDLFNGTCECR 1490
            .:|:..||:|:|||..|...|..|.|.|:|.|.::|||||.|:..||.. .:..||..:|.|:||
Human  1489 RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCR 1553

  Fly  1491 QNIEGRACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGRDCDQCVDGTYNLQ 1555
            .|:.||.||.||.|:..:|.|..|.||:.||...|||.:.|.|:||:||.|..||||..||::|.
Human  1554 PNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLD 1618

  Fly  1556 ESNPDGCTTCFCFGKTSRC-DSAYLRVYNVSLLKHVSITTPEF---HEESIKFDMWPVPADEILL 1616
            .:||.|||.|||||.|.|| .|:|.|...|.:...|.::|...   ||..        |..|:
Human  1619 AANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQ--------PGTEM-- 1673

  Fly  1617 NETTLKADFTLREVNDERPAYFGVL------DYLLNQNNHISAYGGDLAYTLHFTSGFDGKYI-- 1673
                |:||  ||.|.:..|..|..|      .||   .:.:|:|||.|.|.||..:.....::
Human  1674 ----LRAD--LRHVPEAVPEAFPELYWQAPPSYL---GDRVSSYGGTLRYELHSETQRGDVFVPM 1729

  Fly  1674 -VAPDVILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNFQ-TISGKPVSRADFMMVLRDLKVIF 1736
             ..|||:|.....::.......|:.......::.:||.||: |.:...|||.:.||||..|:.:.
Human  1730 ESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQ 1794

  Fly  1737 IRANYWEQTLVTHLSDVYLTLADEDADGTGEYQFLA--VERCSCPPGYSGHSCEDCAPGYYRDPS 1799
            |||.:.:.:....|..|.|.:|.....|.     ||  ||.|.||..|.|.||::||||:|||..
Human  1795 IRALFSQISSAVFLRRVALEVASPAGQGA-----LASNVELCLCPASYRGDSCQECAPGFYRDVK 1854

  Fly  1800 GPYGGYCIPCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCMICACPLP 1864
            |.:.|.|:||:|:|||:.|...:|:|..|||.|||.|||||.:|:. ::.:.....|:.|.|||.
Human  1855 GLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV-SSRDDPSAPCVSCPCPLS 1918

  Fly  1865 FDSNNFATSCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSGNINPEDQG 1929
            ..|||||..|.:  .|.:..|.|||||.|..||.||.||:|.|..:|..|:||:||||.:|....
Human  1919 VPSNNFAEGCVL--RGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLF 1981

  Fly  1930 S-CDTRTGECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDPFVGVCTCHENV 1993
            | ||..||.|..||.:|.|..|.:|||||||:|:...||..|||...||:.|||..|.|.|...|
Human  1982 SDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGV 2046

  Fly  1994 IGDRCDRCKPDHYGFESGVGCRACDCGAASNSTQCDPHTGHCACKSGVTGRQCDRCAVDHWKYEK 2058
            .|.|||||:..|:||:...|||.|.||.|:..::|.|.:|.|.|:.|..|.||..||..:|...:
Human  2047 TGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE 2111

  Fly  2059 DGCTPCNCNQGYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRWVLIKDEG-------CQECNNCH 2116
            .||..|.|..|     .|:|:||:|.|.||:.|:|||.|..:..:....|       |:.|::|.
Human  2112 QGCRRCQCPGG-----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCV 2171

  Fly  2117 HALLDVTDRMRYQIDSV---LEDFNSVTLAFFTSQKLNYYDQLADELEPKVKLLDPNSVDLSPSK 2178
            ..|||..:|....:.::   |...|:.::|:....:||  ..:||
Human  2172 VLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLN--ASIAD-------------------- 2214

  Fly  2179 KANSELESDAKSYAKQVNQTLANAFDIRERSSTTLGNITVAYD------EAVKSADQAKEAIASV 2237
                 |:|..:|.....::| |...::.|:.||:||.     |      :||.:.|||.:.:|..
Human  2215 -----LQSQLRSPLGPRHET-AQQLEVLEQQSTSLGQ-----DARRLGGQAVGTRDQASQLLAGT 2268

  Fly  2238 EAL---SKNLEAAASTKIDAALEQAQHILGQINGTSIELTPNEQVL----EKARKLYE-EVNTLV 2294
            ||.   :|.| .||...:|..|.:.....|.:...:......||:|    |..|.|:| ....|.
Human  2269 EATLGHAKTL-LAAIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLG 2332

  Fly  2295 LPIKAQNKSLNALKNDIGEFSDHLEDLFNWSEASQAKSAD---------VERRNVANQKAFD--- 2347
            .|..|....|.|.:..:....:.|..|:..::|...::.|         ::.|...| :|.|
Human  2333 APQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALN-RAVDATR 2396

  Fly  2348 -----NSKFDTVSEQKLQAEKNIKDAGNFLINGDL-----TLNQINQKLDNLRDALNELNSFNKN 2402
                 ||:.....|:.||.::.: ...|..:...|     ||..:.:.|.:|..|..||.....:
Human  2397 EAQELNSRNQERLEEALQRKQEL-SRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS 2460

  Fly  2403 VD-EELPVREDQHKEADA-----LTDQAEQKAAELAIKAQDLAAQYTDMTAS--AEPAIKAATAY 2459
            :| ...|:.:.....:.|     |.:.||..|.:|...|.:|::...|:...  .:.||:|:.||
Human  2461 LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAY 2525

  Fly  2460 SGIVEAVEAAQKLSQDAISAAGN--ATDKTDGIEERAHLADTGSTDLLQRARQSLQKVQDDLEPR 2522
            |.|::||:||:..:..|:..|.:  ||....|:.:||......||.|.:...|..|::
Human  2526 SRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRL------- 2583

  Fly  2523 LNASAGKVQKISAVNNATEHQLKDINKLIDQLPAESQ-------RDMWKNSN---------ANAS 2571
                 |.|.   |.......||:|:....|||.|..|       .|..:.|.         |.|.
Human  2584 -----GLVW---AALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQ 2640

  Fly  2572 DALEILKNVLEILEPVSVQTPKELEKAHGINRDLDLTNKDVSQANKQLDDVEGSVSKLS----EL 2632
            |....:::.|:.::       :.:|:..|  :...|..:|:.||   :.|...|||.|.    :|
Human  2641 DTATRVQSQLQAMQ-------ENVERWQG--QYEGLRGQDLGQA---VLDAGHSVSTLEKTLPQL 2693

  Fly  2633 AEDIEEQQHR-VGSQSRQLGQEIENLKAQVEAARQLANSIKVGVNFKPSTILELKTPEKTKLLAT 2696
            ...:...::| |.:.|..|...|..::..:..||..|:.:||.:.|...:.::|:||.....||.
Human  2694 LAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAA 2758

  Fly  2697 RTNLSTYFRTTEP-------SGFLLYLGNDNKTAQKNNDFVAVEIVNGYPILTIDLGN-GPERIT 2753
            .|.|..|.:..||       ..|::|:|    :.|...|::.|.:.:........||. ||..::
Human  2759 YTALKFYLQGPEPEPGQGTEDRFVMYMG----SRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLS 2819

  Fly  2754 SDKYVADGRWYQAV-VDR---MGPNAKLTIREEL---PNGDVVEHSKSGYLEGSQNILHVDKNSR 2811
            .|:.:  |..:.|| :||   .| :..:|:..::   ..||.|       ..|::.:|::..:..
Human  2820 IDEDI--GEQFAAVSLDRTLQFG-HMSVTVERQMIQETKGDTV-------APGAEGLLNLRPDDF 2874

  Fly  2812 LF-VGGYPGISDFNAPPDLTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGARERDVLLEKKKP 2875
            :| |||||  |.|..||.|....:.|.||...:.:|.|.|:||           ||...|:....
Human  2875 VFYVGGYP--STFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNF-----------ERTFQLDTAVD 2926

  Fly  2876 VTGLRFKGNGYVQLNATSNLKSRSSIQFSFKADKDTS------------NGLLFFYGRDKHYMSI 2928
            ....|.|..|...|...|.|......:.||.:...|:            :|:|||..:...::.:
Human  2927 RPCARSKSTGDPWLTDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCL 2991

  Fly  2929 EMIDGAIFFNISLGEG-----------------GGVQ----SGSQDRYNDNQWHKVQAER----- 2967
            .:.:|::......|.|                 ..:|    .||:.|.      .|:.||
Human  2992 AVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRV------LVRVERATVYS 3050

  Fly  2968 -ENRNGLLKVDDIVISRTNAPLEADLELPKLRRLY-FGGHPRRLNTSISLQPNFDGCIDNVVINQ 3030
             |..|.|...|...:    ..:..|...|.||||: .||..|             ||:..:....
Human  3051 VEQDNDLELADAYYL----GGVPPDQLPPSLRRLFPTGGSVR-------------GCVKGIKALG 3098

  Fly  3031 GVVDLTEYVTGGGVEEGCSAKFSTVVSYAPHEYGFLR--MNNVSS-DNNLHVVLHFKTTQPNGVL 3092
            ..|||....| .||..||:|......:...|.:||||  ::||:. ..|::....|.:.|.:.:|
Human  3099 KYVDLKRLNT-TGVSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALL 3162

  Fly  3093 FYAANHDQSSTIGL---SLQDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDDVD 3154
            :|.|:.|     ||   |||.|.:.|..:.:: |.......||..|.|........:.|.|||..
Human  3163 YYRASPD-----GLCQVSLQQGRVSLQLLRTE-VKTQAGFADGAPHYVAFYSNATGVWLYVDDQL 3221

  Fly  3155 NKRLG--------SPQPLILEGGD-IFFAGLPDNYRTPRNALASLAYFVGCISDVTVN-----EE 3205
            .:...        .|||   ||.. :...|||::        .::..|.||||:|.|.     :.
Human  3222 QQMKPHRGPPPELQPQP---EGPPRLLLGGLPES--------GTIYNFSGCISNVFVQRLLGPQR 3275

  Fly  3206 IINFANSAEKKNGNIN---GCPPHVLAYEPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTL 3267
            :.:.    ::..|::|   ||.|.:.|..|.|.|....:...:|.:|.::..:..|
Human  3276 VFDL----QQNLGSVNVSTGCAPALQAQTPGLGPRGLQATARKVGTPGASRRSRQP--------- 3327

  Fly  3268 PPTTPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKILTTRPPAKLNLPSDER 3332
                                                               .|.||
Human  3328 ---------------------------------------------------ARHPA--------- 3332

  Fly  3333 CKLPEQPNFDVDFTEAGYRFYGLREQRLQINSLPVKVRRHHDIGISFRTERPNGLLIY-AGSKQR 3396
            |.||  |:...  |...|:|.|.....|:...:..:.|....:.:........|||:: |..:..
Human  3333 CMLP--PHLRT--TRDSYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPG 3393

  Fly  3397 DDFIAVYLLDGRVTYEIR-VGAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLID-----KLEQ 3455
            ...:|::|.:|....::. :|.:|:|:  :......|.||.|.|...:.::.|:.|     ..|.
Human  3394 SPSLALFLSNGHFVAQMEGLGTRLRAQ--SRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEG 3456

  Fly  3456 PGSVDLNAERSAPVLAVELPIYLGGVNKFLESEVKNLTDFKTEVPY---FNGCLKNIKFDAMDLE 3517
            |......||...|     ..:::||:         ..:...:::|.   |:||:|.::.....|.
Human  3457 PHRQHQGAEHPQP-----HTLFVGGL---------PASSHSSKLPVTVGFSGCVKRLRLHGRPLG 3507

  Fly  3518 TPPEEFGVVPC-SEQVERGLFFNNQKAFVKI----FDHFDVGTEMKISFDFRPRDPNGLLFSVHG 3577
            .|....||.|| ...:|.||||......:.:    ....|||.|:::    ||....||:|.:..
Human  3508 APTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEV----RPLAVTGLIFHLGQ 3568

  Fly  3578 KNS--YAILELVDNTLYFTVKTDLKNIVSTNYKLPNNESFCDGKTRNVQAIKSKFVINIAVDFIS 3640
            ..:  |..|::.:..:.... .|.....||:...|:  ..|||:...:..:||..|:.:.|| ..
Human  3569 ARTPPYLQLQVTEKQVLLRA-DDGAGEFSTSVTRPS--VLCDGQWHRLAVMKSGNVLRLEVD-AQ 3629

  Fly  3641 SNPGVGNEGSVITRTNRPLFLGG---HVAFQRAPGIKTKKSFKGCISKVEVNQRMINITPNMVV- 3701
            ||..||...:.......||:|||   .:|.|..|     .::.||:.::.||:..:.:|.::.|
Human  3630 SNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWP-----PAYCGCMRRLAVNRSPVAMTRSVEVH 3689

  Fly  3702 GDIWQGYCP 3710
            |.:....||
Human  3690 GAVGASGCP 3698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LanA	NP_476617.1	LamNT	18..271	CDD:214532	145/265 (55%)
		EGF_Lam	272..>314	CDD:238012	26/41 (63%)
		EGF_Lam	332..389	CDD:238012	29/56 (52%)
		EGF_Lam	402..443	CDD:238012	18/40 (45%)
		EGF_Lam	448..491	CDD:238012	18/43 (42%)
		Laminin_EGF	495..543	CDD:278482	19/47 (40%)
		Laminin_EGF	541..589	CDD:278482	20/47 (43%)
		Laminin_EGF	587..634	CDD:278482	15/46 (33%)
		EGF_Lam	631..673	CDD:238012	20/42 (48%)
		Laminin_EGF	677..729	CDD:278482	20/53 (38%)
		Laminin_EGF	732..782	CDD:278482	22/49 (45%)
		EGF_Lam	785..828	CDD:238012	15/42 (36%)
		CBM6-CBM35-CBM36_like	831..966	CDD:271143	41/139 (29%)
		Laminin_EGF	1375..1423	CDD:278482	24/47 (51%)
		EGF_Lam	1420..1457	CDD:238012	15/36 (42%)
		Laminin_EGF	1466..1516	CDD:278482	21/50 (42%)
		Laminin_EGF	1514..1562	CDD:278482	24/47 (51%)
		LamB	1632..1760	CDD:214597	38/137 (28%)
		Laminin_EGF	<1775..1801	CDD:278482	14/25 (56%)
		EGF_Lam	1808..1851	CDD:238012	21/42 (50%)
		EGF_Lam	1859..1907	CDD:214543	25/47 (53%)
		EGF_Lam	1916..1968	CDD:238012	27/52 (52%)
		EGF_Lam	1969..2015	CDD:238012	22/45 (49%)
		EGF_Lam	2016..>2054	CDD:238012	15/37 (41%)
		EGF_Lam	2063..>2097	CDD:238012	15/33 (45%)
		Laminin_I	2129..2385	CDD:283627	62/294 (21%)
		Tar	2278..2662	CDD:223910	101/441 (23%)
		Laminin_II	2566..2700	CDD:283628	34/147 (23%)
		LamG	2674..2843	CDD:238058	48/184 (26%)
		LamG	2878..3029	CDD:238058	38/190 (20%)
		LamG	3078..3205	CDD:214598	37/143 (26%)
		LamG	3349..3512	CDD:238058	34/172 (20%)
		LamG	3535..3689	CDD:238058	41/162 (25%)
LAMA5	XP_006723859.1	Laminin_N	54..298	CDD:278484	136/244 (56%)
		EGF_Lam	299..347	CDD:238012	30/48 (63%)
		EGF_Lam	358..421	CDD:238012	30/62 (48%)
		EGF_Lam	428..470	CDD:238012	18/41 (44%)
		EGF_Lam	494..541	CDD:214543	20/47 (43%)
		EGF_Lam	540..583	CDD:238012	16/42 (38%)
		Laminin_EGF	587..634	CDD:278482	20/47 (43%)
		Laminin_EGF	632..679	CDD:278482	15/46 (33%)
		EGF_Lam	676..718	CDD:238012	19/41 (46%)
		EGF_Lam	775..827	CDD:238012	23/51 (45%)
		EGF_Lam	828..>867	CDD:238012	13/38 (34%)
		Laminin_EGF	1438..1486	CDD:278482	24/47 (51%)
		Laminin_EGF	1528..1579	CDD:278482	21/50 (42%)
		Laminin_EGF	1577..1625	CDD:278482	24/47 (51%)
		Laminin_B	1693..1818	CDD:278481	35/127 (28%)
		Laminin_EGF	1864..1913	CDD:278482	21/49 (43%)
		Laminin_EGF	1913..1966	CDD:278482	27/54 (50%)
		EGF_Lam	1968..2021	CDD:238012	27/52 (52%)
		EGF_Lam	2023..2067	CDD:214543	21/43 (49%)
		EGF_Lam	2069..2115	CDD:238012	17/45 (38%)
		Laminin_EGF	2117..>2145	CDD:278482	15/32 (47%)
		Laminin_I	2188..2450	CDD:283627	64/297 (22%)
		TorS_sensor_domain	2287..2578	CDD:293930	68/292 (23%)
		PspA_IM30	2435..2695	CDD:281941	70/286 (24%)
		Laminin_II	2641..2762	CDD:283628	31/132 (23%)
		LamG	2781..2908	CDD:214598	37/142 (26%)
		LamG	2943..3095	CDD:238058	34/174 (20%)
		LamG	3124..3267	CDD:238058	44/159 (28%)
		LamG	3345..3502	CDD:238058	34/172 (20%)
		LamG	3526..3676	CDD:238058	41/162 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	306	1.000	Domainoid score	I1363
eggNOG	1	0.900	-	-		E1_KOG1836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4060
Inparanoid	1	1.050	1861	1.000	Inparanoid score	I61
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45870
OrthoDB	1	1.010	-	-		D1919at33208
OrthoFinder	1	1.000	-	-		FOG0003375
OrthoInspector	1	1.000	-	-		oto91540
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	1	1.000	-	-		X3259
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870