DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LanA and lama5

DIOPT Version :9

Sequence 1:	NP_476617.1	Gene:	LanA / 38723	FlyBaseID:	FBgn0002526	Length:	3712	Species:	Drosophila melanogaster
Sequence 2:	XP_009294934.1	Gene:	lama5 / 321243	ZFINID:	ZDB-GENE-030131-9823	Length:	3665	Species:	Danio rerio

Alignment Length:	3927	Identity:	1307/3927 - (33%)
Similarity:	1937/3927 - (49%)	Gaps:	489/3927 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GVASIGALLVILAISYCQAELT---------------PPYFNLATGRKIYATATCGQD-TDGP-- 50
            |.||...:||.|.:......||               |||||||.|.||.||||||.| .:.|
Zfish     7 GRASRTPVLVFLPLLLLTGTLTAQELPVNGVNGFSLHPPYFNLAEGTKITATATCGVDENEQPIQ 71

  Fly    51 ELYCKLVGANTEHDHIDYSVIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEV 115
            :|||||||.....|  ....||||.||.|......|.||..|||||||.|||||||||..|.|:|
Zfish    72 DLYCKLVGGPVSGD--PSQTIQGQYCDICSSQDTNRAHPISNAIDGTERWWQSPPLSRSAKHNQV 134

  Fly   116 NLTINFEQEFHVAYLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPI 180
            |:|::..|.|||||:.|:..|||||.||.||:|.|:|||:.|||.|:.:..||...||:.|.:.|
Zfish   135 NVTLDLGQLFHVAYVLIKFANSPRPDLWVLERSIDFGKTYQPWQFFASSKRDCIERFGQRTIERI 199

  Fly   181 TRDDDVICTTEYSKIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGH 245
            ..|||||||||||:|||||||||.|.|:|.||.:.|:..|.||:|:|:|||:|:|.|||..||||
Zfish   200 YHDDDVICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPVLREFTKATNIRLRFLRTNTLLGH 264

  Fly   246 LMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNEC 310
            ||....:||||||||:||||||||||||:|||||:.|:.:||..|.: |.|.|||:|||..|:.|
Zfish   265 LMGKTLRDPTVTRRYYYSIKDISIGGRCVCNGHAEACNAQDPNDPYK-LQCDCQHNTCGTSCDRC 328

  Fly   311 CPGFEQKKWRQNTNARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTV 375
            ||||.|..|:..|......|||||||.||:||.||.|::::..|||:.|.|:|||||..|||:|.
Zfish   329 CPGFNQFPWKPATTYSANECEPCNCHRHSSECYYDPEIDQRRSSLDMQGEYNGGGVCVECQHHTT 393

  Fly   376 GINCNKCKPKYYRPKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYY 440
            |:||.:|.|.|||...........||.|||:..|:.|.||:.||.|.|:..:...:||.||.||.
Zfish   394 GVNCERCIPGYYRSPDHPLESPFACSKCQCESEFTEGTCEDRTGRCYCKPNYTGENCDQCAEGYE 458

  Fly   441 GYPNCR----------------ECECNLNGTNGYHCEAE-SGQQCPCKINFAGAYCKQCAEGYYG 488
            .:|.|.                :||||..||.|..|..: ....|.||..|.|.:|..|:.||:.
Zfish   459 HFPECYQVLINGEVRPAGENIIDCECNAAGTEGNSCRPDPRTNTCVCKPEFTGEHCDTCSHGYFS 523

  Fly   489 FPECKACECNKIGSITNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEIC 553
            . .|:.|:|:..|.:...|:..||:|.|.:.|.|.:||:|..||||||.|.||.|...|:..|:|
Zfish   524 I-NCQRCQCSGQGCLDGSCDAVTGQCVCRSGFQGYSCEQCAPGYFNYPLCQYCGCSVVGSIPEMC 587

  Fly   554 NKQSGQCICREGFGGPRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTL 618
            : .:|:|:||..|.|||||||..||::||:|:.|.|....|...:|....:|||..|::|.:|..
Zfish   588 D-PAGRCLCRPEFTGPRCDQCQSGFHSYPNCQVCTCDPRTSLDSSCSELDQCNCRPNYSGPRCQQ 651

  Fly   619 CTAGYYSYPDCLPCHCDSHGSQGVSCNS-DGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPA 682
            |..||||||.|.||.|...||:..||:. .|||:|.||.:|::||||..|.|.||.|:...|:||
Zfish   652 CAPGYYSYPSCTPCDCSVEGSRSSSCDPVSGQCVCLPNIEGQRCDSCSPGSYGFPLCQLGTCNPA 716

  Fly   683 GVI--DKFAGCGSVPVGELCKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDT 745
            |.:  |.....||      |.|:..|.|..|..||||||||:.....||..|||.|.||:|.:..
Zfish   717 GSVHNDILPTVGS------CVCRPYVEGVACERCKPLYWNLSPDTIYGCSTCDCNTAGTLSEVAE 775

  Fly   746 CTSKSGQCPCKPHTQGRRCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRI 810
            ||.::|||.|||:.....|..|:||.|:|...|.|||:.|.||:|||....||:..|:|:|.|.:
Zfish   776 CTQRTGQCFCKPNVCSGTCNVCKDGFFNLQKDSYFGCQGCQCDIGGSVGQACDERYGRCRCRPNV 840

  Fly   811 TGLACTQPLTTHFFPTLHQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNE 875
            .|..|.||...|:||.||..::|.|||:...|..||:.|:...|..||.:||...:.||..|..|
Zfish   841 EGPKCKQPRPDHYFPDLHHMKFEVEDGTTMDGRPVRFGYNPLEFESFSWRGYAQMSPIQPRVLVE 905

  Fly   876 VNVFKSSLYRIVLRYVNPNAENVTATISVTSDNPLEVDQHV----------KVLLQPTSEPQFVT 930
            |.|....|:.:||.|||....:||..:||..|.     :||          :::..|:|||.||.
Zfish   906 VVVGSPDLFHVVLHYVNRGGVDVTGQVSVIEDG-----RHVLCGNCSEQSKQIVFAPSSEPTFVN 965

  Fly   931 VAGPLGVKPSAIVLDPGRYVFTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPCELGN----ME 991
            |.....|:|  .||:||.:....:| :.::|||.||||:|||||.||...::.||...:    .:
Zfish   966 VPQNSFVEP--FVLNPGTWTVIIEA-EGILLDYLVLLPSAYYEAPILQLQVTEPCSYSHTQDASQ 1027

  Fly   992 LCRHYKYASVEVFSPAATPFVIGENSKPTNPVETYTDPEHLQIVSHVGDI-------PVLSGSQN 1049
            .|..|.|.|::.|.           |..:|.....:| .||....|...|       .:.||:..
Zfish  1028 NCLQYMYLSLDEFP-----------SISSNDASCRSD-NHLPRPCHTEKITPRHPSMAICSGNDI 1080

  Fly  1050 ELHYIVDVPRSGRYIFVIDYISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICRTSVNEDG 1114
            .:.....||..|.|:.|::|.|:...|.:..:::........:..:.|..|.||.:|| ||:.|.
Zfish  1081 SVGLRGRVPVPGEYVLVVEYASEDQAPQNLTVSVSSAGESTHQEQITLLHCKYSFLCR-SVSVDD 1144

  Fly  1115 MEKSFYINKEDLQPVIISADIE-----DGSRFPIISVTAIPVDQWSIDYINPSPVCV-IHDQ--- 1170
            |::        :....|||:.|     :.|.|.:..|..||..|::::|:.|...|: .|..
Zfish  1145 MKR--------VALFTISANAEIQLIAERSSFFLHKVFLIPRAQFTMEYLKPRVHCISTHGHFAP 1201

  Fly  1171 ---QCATPKFRSVPDSKKI-EFETD---------------HEDRIATNKPPYASLDERVKLVHLD 1216
               .|...:|::.|.|..: |.:..               :.||..|:.||.|:  :..:.|.||
Zfish  1202 DSGSCIPSRFQNPPQSLVLKEGQASSVAEPILASAPDPSLYADRPMTSTPPTAT--DNTEHVLLD 1264

  Fly  1217 SQNEATIVIESKVDATKPNLFVILVKYYQPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRG 1281
            :...| :|..::|.|.  ..:|.::.|:||.||.|.|...:..|: .:.|..:...||...|||.
Zfish  1265 TSQNA-VVYSTRVHAL--GRYVFILHYHQPLHPTYNVQVFINGGR-IWQGNVNASFCPHGYGCRS 1325

  Fly  1282 VIRPAGEGSFEI-DDEFKFTITTDRSQSVWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHD 1345
            |:....:...:: |.|...|:.....:::||||::|||...|:...|.||..|::.:||.|||.:
Zfish  1326 VVMSENQIILDVTDHEVILTLRVPDRKTLWLDYVLVVPEGSYSSSFLSEELLDKSYDFISNCGQN 1390

  Fly  1346 HFHIT-HNASDFCKKSVFSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACR 1409
            .|:|. .:||.||..|..||::.:|:||:||.|...|:.|..|..|||||:|:||||.|.|..|.
Zfish  1391 SFYINPSSASAFCLSSAVSLSSFFNNGAVPCGCHEVGAESDTCESFGGQCRCRPNVIGRDCSQCA 1455

  Fly  1410 SRYYGFPDCKPCKCPNSAMCEPTTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIA 1474
            :.|||||:|:||.| .|.:|||.||||:|||..:...|..|.|.|:|.|.::|||.|.|:..|:.
Zfish  1456 TGYYGFPNCRPCNC-GSRLCEPVTGECICPPRTLQPDCVTCEPQTFGCHPLVGCEMCNCSRPGVT 1519

  Fly  1475 NGNSQCDLFNGTCECRQNIEGRACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNV 1539
            :.:..||..||.|.||.||.||.||.||.|::.:|:|..|:|::.|||:.|||...|.|.||:||
Zfish  1520 SMDISCDTNNGQCRCRNNIVGRQCDRCSPGFYGYPNCRPCNCNEAGTEMNVCDSFTGRCLCKENV 1584

  Fly  1540 VGRDCDQCVDGTYNLQESNPDGCTTCFCFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEESIKF 1604
            .|..||||..||::|..:|..|||.|||||.|.||.|:..|...:..:....:         ::.
Zfish  1585 EGPRCDQCKLGTFHLDPTNAKGCTKCFCFGATDRCHSSDKRRSEIMDMAGWVL---------LRS 1640

  Fly  1605 DMWPVPADEILLNETTLKADFTLREVND-------ERP-AYFGVLDYLLNQNNHISAYGGDLAYT 1661
            |...||. ...|::..::||  |.:|.|       ..| ||.|         :.:|:|||.|.|.
Zfish  1641 DRQEVPV-STYLDQDLVEAD--LSDVPDVSQDLHWHAPQAYLG---------DKVSSYGGYLRYR 1693

  Fly  1662 LHFTSGFDGKYI----VAPDVILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNFQ-TISGKPVS 1721
            ||..:.....::    :.|||||......||:...|.||..:|....|::||.:|: ..:|..||
Zfish  1694 LHTQTMRGDAFLMVETIRPDVILKGNQMTLVYMEREYPSPEDPHEGIVHLVEESFRHAQTGNSVS 1758

  Fly  1722 RADFMMVLRDLKVIFIRANYWEQTLVTHLSDVYLTLADEDADGTGEYQFLAVERCSCPPGYSGHS 1786
            |.:.||||..|:.:.|||.:.:......|....|.:|:....|.....   ||.|.||..|.|.|
Zfish  1759 REELMMVLVALESLQIRALHSQSAQSVSLRAAVLEVAENMPSGRHANN---VEICLCPGNYLGDS 1820

  Fly  1787 CEDCAPGYYRDPSGPYGGYCIPCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNAT-N 1850
            |:.||||||||..|.:.|.|:||.|||||:.|...:|||..|:|.|.|:|||:|:.|::.|.| :
Zfish  1821 CQQCAPGYYRDNKGLFLGKCVPCNCNGHSDQCLDGSGICVNCRHNTAGNHCEKCLGGFHHNNTVD 1885

  Fly  1851 GTPGDCMICACPLPFDSNNFATSCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCK 1915
            |....|..|.|||...|||||..|  .|..:.:.|.|.|||.|.:||.||.|:||.|..||..|:
Zfish  1886 GHSVSCSSCPCPLQVASNNFAIRC--VEKPNNMRCLCMPGYAGSKCERCAPGYYGNPVVIGSTCQ 1948

  Fly  1916 PCECSGNINPEDQGS-CDTRTGECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQT 1979
            ||.|:||.:|....| |...||||..|::||.|..|.:||||||||||..|||..|:|...||..
Zfish  1949 PCNCNGNSDPNMLFSDCHPLTGECQSCMHNTAGPHCEICAPGFYGDAITAKNCTRCNCSPCGTAH 2013

  Fly  1980 CDPFVGVCTCHENVIGDRCDRCKPDHYGFESGVGCRACDCGAASNSTQ-CDPHTGHCACKSGVTG 2043
            ||...|.|.|...|:|.:||||:...:||:|..|||.|||.|::...| |||..|.|||:.||.|
Zfish  2014 CDSHTGQCHCKPGVVGAQCDRCEHGTFGFDSCTGCRKCDCDASAALVQACDPVNGACACQPGVNG 2078

  Fly  2044 RQCDRCAVDHWKYEKDGCTPCNCNQGYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRWVLIKDEG 2108
            ..|.:||..||.|..:||..|.|     :|..|:|.||:|:|..|:.|.:||.|.::..:....|
Zfish  2079 PNCHQCAPGHWNYSSNGCRKCEC-----KGGRCDPRTGECRCTTGLTGKQCDTCLSQHSVPVQNG 2138

  Fly  2109 ----CQECNNCHHALLDVTDRMRYQIDSV---LEDFNSVTLAFFTSQKLN-----------YYDQ 2155
                ||.|::|...||:..||:.:..:||   |...|:.|.|:....:||           .|:.
Zfish  2139 ADMHCQPCDSCVMVLLEDLDRISHFYESVANQLTSLNASTFAWTQLNRLNASIADIANAITNYNS 2203

  Fly  2156 LADE-------LEPKVKLLDPNSVDL----SPSKKANSELESDAKSYAKQVNQ-------TLANA 2202
            ..|:       ||.:::::|.:..||    |.::|....||.:..|...:..:       .:.:.
Zfish  2204 TLDKSRNRASVLEGELEIIDSDIKDLEKKASVTQKKKDALEDNINSTHTRAQELFGFIKGIMRDV 2268

  Fly  2203 FDIRERSSTTLGNITVAYDEAVKSADQAKEAIASVEALSKNLEAAA----STKIDAALEQAQHIL 2263
            .||.::.:.|..|.|...||    .|.|:: ||.||::.:::....    ..|....|:||.:::
Zfish  2269 KDIIQQVNRTAQNETQVMDE----KDLARK-IAEVESMLRDMRFRGFDYQKNKAKNELDQANNLV 2328

  Fly  2264 GQ-INGTSIELTPNEQVLEKARKLYEEVNTLVLPIK-AQNKSLN-----ALKNDIGEFSDHLEDL 2321
            .: ||..:.....||.|.|..|...::.|..::.:: |.|:::|     ...|:|.:  .|||||
Zfish  2329 DRVINEIANRTWNNEAVAENIRNKLKQFNEQLMDLRDAMNEAVNNTAQTVEANNINQ--KHLEDL 2391

  Fly  2322 FNWSEASQAKSADVERRNVANQKAFD--NSKFDTVSEQKLQAEKNIKDAGNFLINGDLTLNQINQ 2384
                                 ||..:  :.|:..|..|...||.::              .|:|.
Zfish  2392 ---------------------QKKVNSLHEKYKEVVSQLQMAEDDV--------------TQVND 2421

  Fly  2385 KLDNLRDALNELNSFNKNVD-EELPVREDQHKEADA-----LTDQAEQKAAELAIKAQDLAAQYT 2443
            .|..|:|:..:.......:| ...|:.|...|.|.|     |.:.||:.|..|...|.:|::..:
Zfish  2422 LLSMLQDSKEDYEHLAAQLDGARQPLAEKVQKYAPAANKIPLVEAAEKHAEMLEQLANNLSSLIS 2486

  Fly  2444 DMTAS--AEPAIKAATAYSGIV----EAVEAAQKLSQDAISAAGNATDKTDGIEERAHLADTGST 2502
            .....  .:.|:.|:.||:.|:    ||...|.|.::.|..|..|..||  .:..:|......||
Zfish  2487 GSNQDNFIQRALNASRAYTNIINSVLEAETTALKANETASMALENIRDK--DLPAQAAALKNQST 2549

  Fly  2503 DLLQRARQSLQKVQDDLEPRLNASAGKVQKISAVNNATEHQLKDINKLIDQLPAESQRDMWKNSN 2567
            :||:.| :.|......|:||::..  |:..:.| ....|..|:|:..:.::|  ...||...||.
Zfish  2550 ELLKSA-EELNNSSQSLKPRVDTI--KMSLLDA-EKKKEKMLQDLKDIQNKL--NVSRDDIVNSI 2608

  Fly  2568 ANASDALE----ILKNVLEILEPVSVQTPKELEKAHGINRDLDLTNKDVSQANKQLDDVEGSVSK 2628
            :.|..|:|    .:.||..:|.|:..|. :|.:|.:|   |.:.|::|:   ||.|:|...||:.
Zfish  2609 SAAKSAVEQANNTVANVSGVLAPIQKQL-EEWQKQYG---DSNATSEDI---NKALNDANTSVAA 2666

  Fly  2629 LSE-LAEDIE--EQQHRVGSQSRQLGQEIENLKAQVEAARQLANSIKVGVNFKPSTILELKTPEK 2690
            ||: |.:.|:  ::.|....|...:...|:.::..:|.||..||.:.|.:.|...:.::::||..
Zfish  2667 LSDTLPKLIKKLDRLHNTTFQPSNISDSIQRIRQLIEQARNAANKVSVSMQFNGKSGVQVRTPSN 2731

  Fly  2691 TKLLATRTNLSTYFRTTEPS------------GFLLYLGNDNKTAQKNNDFVAVEIVNGYPI-LT 2742
            ...||..::|..|.:...|:            .|:|||||    ...:.:::||.: ||..: ..
Zfish  2732 VADLAAYSSLQMYIKLPSPTIKKKRQTEATNPQFVLYLGN----RDSSKEYMAVTL-NGKKLRWH 2791

  Fly  2743 IDLGNGPERITSDKYVADGRWYQAVVDRMGPNAKLTIREELPNGDVVEHSKSGYLEGSQNILHVD 2807
            .::|.....:..|:.|.:..:.:.:::|.....::::..:....::::.....  :|.:.:|::.
Zfish  2792 FNVGGSSVDVLMDEDVKNDFFNKLILERTLQYGQMSMTTDQDENNIIKRIMEA--KGQKGLLNLP 2854

  Fly  2808 KNSRLF-VGGYPGISDFNAPPDLTTNS----FSGDIEDLKIGDESVGLWNFVYGDDNDQGARERD 2867
            ....:| |||:|  |.|:.|..|..:|    |.|.:|.|.|.:|.:.|:||....|.:   ...|
Zfish  2855 AEETVFYVGGFP--STFSPPGTLNLSSPLDFFKGYVELLSINEELISLYNFEQTFDMN---TTTD 2914

  Fly  2868 VLLEKKKP-------VTGLRFKGNGYVQLNATSNLKSRSSIQFSFKADKDTSNGLLFFYGRDKHY 2925
            ....:|:|       |.|:.|.|.|||::...:....|:   |.......:.||:|..:.|:..|
Zfish  2915 APCSRKRPANTPEWVVDGVYFDGTGYVEVLFETQKGDRT---FDQTIRLISQNGILLSFQREDKY 2976

  Fly  2926 MSIEMIDG--AIFFNI--SLGEGGGVQSGSQDRYNDNQWHKVQAERENRNGLLKVDDIVISRTNA 2986
            ::|.::||  .:|:|:  ||..|.|  :.::....|.:..:|..:..|...|:::|    ..|..
Zfish  2977 VTIAVLDGFLRVFYNVEGSLMPGPG--NPTKISNADKKTLQVILQLNNMKMLVRLD----RETLY 3035

  Fly  2987 PLEADLELPKLRRLYFGG-----HPRRLNTSISLQPNFDGCIDNVVINQGVVDLTEYVTGGGVEE 3046
            .|.:: ||....|.:.||     .|..|.:......:..||. .::.:.|.....:.:...|:..
Zfish  3036 TLYSE-ELNFTGRYFLGGVPEAEMPNDLKSIYLKHGSIRGCF-RIIKSMGSFVQIKTMKSSGISF 3098

  Fly  3047 GC--SAKFSTVVSYAPHEYGFLRMNNVSSDNNLHVVLHFKTTQPNGVLFYAANHDQSSTIGLSLQ 3109
            ||  ...|:....:....|..|:|:.|...|:.:..:.|:|.|.||::||..|.|  :...:.|.
Zfish  3099 GCPDDLLFTREAHFTGEGYLGLKMDYVDLANSFYGGIGFRTDQQNGLMFYHQNKD--NVCKVMLD 3161

  Fly  3110 DGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDDVDNKRLGSPQPLILEGGDIFFA 3174
            :|.: |.|...:.|...:..||..:|.|.|...|..|.:.:|||            ||.     :
Zfish  3162 NGHV-LVSTDRKEVKSQKTYNDDNNHYVAVYRDQNVLSIYIDDV------------LES-----S 3208

  Fly  3175 GLPDNYRTPRNALASLAYFVGCISDVTVNEEIINFANSAEKKNG--NINGCPPHVLAYEPSLVPS 3237
            |...|..|.||||                :|...:.....:.||  |:.||           :.:
Zfish  3209 GETGNVTTRRNAL----------------QEGFTYVGGTPESNGPTNLTGC-----------ISN 3246

  Fly  3238 YYPSGDNEVESPWSNADTLPPLKPDIESTLPPTTPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVI 3302
            ::....||           |.:..|:::.|                    .....|.|.|
Zfish  3247 FFIKRANE-----------PQIVEDLKTAL--------------------EGRKYTFTCP----- 3275

  Fly  3303 DEEKEIEAKTPQKILTTRPPAKLNLPSDERCKLPE---QPNFDVDFTEAGYRFYGLREQRLQINS 3364
                  :|..|.::|.:..|.|.|.|.:.|.::..   |.:..|...:| :.|.|.....::.:|
Zfish  3276 ------DASAPLQMLNSPRPKKQNAPGNSRSRMARDSCQGDTSVQEVDA-HHFSGSTHSHMRFDS 3333

  Fly  3365 LPVKVRRHHDIGISFRTERPNGLLIYAGSKQRDDFIAVYLLDGRVTYEIRVGAQLQAKITTEAEL 3429
            ||....:.....||.|....:||:.:....:....:|:.:.||.:|..:. |.:.:..|.::...
Zfish  3334 LPQAFSKAPHFSISVRVNSSSGLIFHVAGGKGQRMMALSVSDGHLTLLVN-GGKRKTSIRSKKRY 3397

  Fly  3430 NDGTWHTVEVVRTQRKVSLLIDKLEQPGSVDLNAERSAPVLAV-ELPIYLGGVNKFLESEVKNLT 3493
            :||.||||.|.....:.||.:|.::..     |...||...:: ..|:|:||:.          .
Zfish  3398 SDGLWHTVFVKVEGDRGSLTVDGIDTQ-----NKRVSAGGKSMFAAPLYIGGLP----------V 3447

  Fly  3494 DFKTEVPYFNGCLKNIKFDAMDLETPPEEFGVVPCSEQ-VERGLFFNNQKAFVKIFDHFDVGTEM 3557
            |....:..|.||::::|.:.:.|::|....||.||.:| ::.|..|:::..|:.|.:...:|.::
Zfish  3448 DHSAAMAGFVGCVRDLKLNEVSLQSPSVSVGVTPCYQQPLQPGAHFSSRGGFMTIDESLVLGQDL 3512

  Fly  3558 KISFDFRPRDPNGLLFSVHGKNSYAILELVDNTLYFTVKTDLKNIVSTNY--KLPNNESFCDGKT 3620
            :|..:.|....:|||.....|.::.:...::....    |.|.|..|..:  .|...||.|||..
Zfish  3513 EIQLEVRLDSGSGLLLHTGAKKTHQLSVYLEQGQV----TVLMNSGSGEFSVSLTPKESLCDGGW 3573

  Fly  3621 RNVQAIKSKFVINIAVDFISSNPGVGNEGSVITRTNRPLFLGGHVAFQRAPGIKTK-KSFKGCIS 3684
            ..:..:|...||.:.||..|.: ||..:.|........::|||.......||:.:. :||:||:.
Zfish  3574 HTIAIVKKSNVIQLHVDSFSEH-GVAPKQSRSNGGKEAVYLGGLPETITVPGLSSSVQSFQGCVR 3637

  Fly  3685 KVEVNQRMINIT-PNMVVGDIWQGYCP 3710
            |..:|.|.:.:: |..|.|.:....||
Zfish  3638 KAVLNHRPVMLSKPLSVSGSVGTQGCP 3664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LanA	NP_476617.1	LamNT	18..271	CDD:214532	151/270 (56%)
		EGF_Lam	272..>314	CDD:238012	23/41 (56%)
		EGF_Lam	332..389	CDD:238012	33/56 (59%)
		EGF_Lam	402..443	CDD:238012	17/40 (43%)
		EGF_Lam	448..491	CDD:238012	17/43 (40%)
		Laminin_EGF	495..543	CDD:278482	22/47 (47%)
		Laminin_EGF	541..589	CDD:278482	23/47 (49%)
		Laminin_EGF	587..634	CDD:278482	20/46 (43%)
		EGF_Lam	631..673	CDD:238012	21/42 (50%)
		Laminin_EGF	677..729	CDD:278482	20/53 (38%)
		Laminin_EGF	732..782	CDD:278482	23/49 (47%)
		EGF_Lam	785..828	CDD:238012	19/42 (45%)
		CBM6-CBM35-CBM36_like	831..966	CDD:271143	49/144 (34%)
		Laminin_EGF	1375..1423	CDD:278482	26/47 (55%)
		EGF_Lam	1420..1457	CDD:238012	18/36 (50%)
		Laminin_EGF	1466..1516	CDD:278482	22/49 (45%)
		Laminin_EGF	1514..1562	CDD:278482	23/47 (49%)
		LamB	1632..1760	CDD:214597	43/140 (31%)
		Laminin_EGF	<1775..1801	CDD:278482	15/25 (60%)
		EGF_Lam	1808..1851	CDD:238012	22/43 (51%)
		EGF_Lam	1859..1907	CDD:214543	24/47 (51%)
		EGF_Lam	1916..1968	CDD:238012	29/52 (56%)
		EGF_Lam	1969..2015	CDD:238012	19/45 (42%)
		EGF_Lam	2016..>2054	CDD:238012	18/38 (47%)
		EGF_Lam	2063..>2097	CDD:238012	13/33 (39%)
		Laminin_I	2129..2385	CDD:283627	64/300 (21%)
		Tar	2278..2662	CDD:223910	100/410 (24%)
		Laminin_II	2566..2700	CDD:283628	39/140 (28%)
		LamG	2674..2843	CDD:238058	38/186 (20%)
		LamG	2878..3029	CDD:238058	38/159 (24%)
		LamG	3078..3205	CDD:214598	33/126 (26%)
		LamG	3349..3512	CDD:238058	38/163 (23%)
		LamG	3535..3689	CDD:238058	40/156 (26%)
lama5	XP_009294934.1	Laminin_N	51..290	CDD:278484	142/240 (59%)
		EGF_Lam	291..339	CDD:238012	27/48 (56%)
		EGF_Lam	350..413	CDD:238012	34/62 (55%)
		EGF_Lam	421..463	CDD:214543	18/41 (44%)
		EGF_Lam	482..529	CDD:214543	18/47 (38%)
		Laminin_EGF	529..577	CDD:278482	22/47 (47%)
		Laminin_EGF	575..622	CDD:278482	23/47 (49%)
		Laminin_EGF	620..667	CDD:278482	20/46 (43%)
		EGF_Lam	664..711	CDD:238012	23/46 (50%)
		Laminin_EGF	713..759	CDD:278482	20/51 (39%)
		Laminin_EGF	762..812	CDD:278482	23/49 (47%)
		EGF_Lam	815..858	CDD:238012	19/42 (45%)
		Laminin_EGF	1421..1469	CDD:278482	26/47 (55%)
		Laminin_EGF	1511..1561	CDD:278482	22/49 (45%)
		Laminin_EGF	1559..1607	CDD:278482	23/47 (49%)
		Laminin_B	1672..1796	CDD:278481	41/132 (31%)
		EGF_Lam	1842..1881	CDD:238012	20/38 (53%)
		Laminin_EGF	1894..1947	CDD:278482	27/54 (50%)
		EGF_Lam	1949..2002	CDD:238012	29/52 (56%)
		Laminin_EGF	2004..2048	CDD:278482	18/43 (42%)
		Laminin_EGF	2051..2099	CDD:278482	23/47 (49%)
		Laminin_EGF	2099..>2128	CDD:278482	13/33 (39%)
		mycoplas_twoTM	2158..>2351	CDD:275320	45/197 (23%)
		Laminin_I	2171..2429	CDD:283627	64/299 (21%)
		COG1340	2319..2558	CDD:224259	66/278 (24%)
		BAR	2383..2637	CDD:299863	73/299 (24%)
		Laminin_II	2611..2741	CDD:283628	38/136 (28%)
		LamG	2757..2896	CDD:214598	31/147 (21%)
		LamG	2932..3075	CDD:238058	36/152 (24%)
		LamG	3110..3249	CDD:238058	44/185 (24%)
		LamG	3320..3466	CDD:238058	38/161 (24%)
		LamG	3490..3642	CDD:238058	40/156 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	303	1.000	Domainoid score	I1364
eggNOG	1	0.900	-	-		E1_KOG1836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4060
Inparanoid	1	1.050	2015	1.000	Inparanoid score	I47
OMA	1	1.010	-	-		QHG45870
OrthoDB	1	1.010	-	-		D1919at33208
OrthoFinder	1	1.000	-	-		FOG0003375
OrthoInspector	1	1.000	-	-		oto40621
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	1	1.000	-	-		X3259
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870