DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LanA and epi-1

DIOPT Version :9

Sequence 1:	NP_476617.1	Gene:	LanA / 38723	FlyBaseID:	FBgn0002526	Length:	3712	Species:	Drosophila melanogaster
Sequence 2:	NP_001294008.1	Gene:	epi-1 / 177956	WormBaseID:	WBGene00001328	Length:	3715	Species:	Caenorhabditis elegans

Alignment Length:	3893	Identity:	1344/3893 - (34%)
Similarity:	2009/3893 - (51%)	Gaps:	384/3893 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALLVILAI----SYCQAELTPPYFNLATGRKIYATATCGQDTDGP--ELYCKLVGANTEHDHID- 67
            ||.:|:.:    :|.|. |||....::..:.|.||:|||:....|  |:||.|.| :|::..::
Worm    13 ALFLIVTLLAQFTYSQV-LTPSQITISHRKPITATSTCGEIQGQPVTEIYCSLTG-STQYTPLNS 75

  Fly    68 YS-----------------VIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEV 115
            ||                 |..|..|.:|: ...|.:||..|.:||..:||.|||||||::.|||
Worm    76 YSYQDDEQQKSWSQYENPMVRGGHGCGHCN-AGNENSHPAANMVDGNNSWWMSPPLSRGLQHNEV 139

  Fly   116 NLTINFEQEFHVAYLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPI 180
            |:||:.||||||||::|:|.||||||.|.||:|||:|||:.||.:|::..|:|...||.::..||
Worm   140 NITIDLEQEFHVAYVWIQMANSPRPGSWVLERSTDHGKTYQPWFNFAENAAECMRRFGMESLSPI 204

  Fly   181 TRDDDVICTTEYSKIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGH 245
            :.||.|.|.|:.:.:.||||.|:.:.:|..||||..:..|..||.:|||||||:|||.|:.|.||
Worm   205 SEDDSVTCRTDMASLQPLENAEMVIRILEHRPSSRQFATSEALQNFTRATNVRLRLLGTRTLQGH 269

  Fly   246 LMSVAR-QDPTVTRRYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNE 309
            ||.:.. :||||||||||:||:|.|||||:|||||.|||:.:|:.| :.|.|||:|:|||..|..
Worm   270 LMDMNEWRDPTVTRRYFYAIKEIMIGGRCVCNGHAVTCDILEPQRP-KSLLCRCEHNTCGDMCER 333

  Fly   310 CCPGFEQKKWRQNTNARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNT 374
            |||||.||:|:..|....|.||.|||.|.||||:||.||:....|:|..|:|:|||||:||:.||
Worm   334 CCPGFVQKQWQAATAHNNFTCEACNCFGRSNECEYDAEVDLNKQSIDSQGNYEGGGVCKNCRENT 398

  Fly   375 VGINCNKCKPKYYRPKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGY 439
            .|:|||||...|:||:|..|||...|..|.||....||.|.||||.|||...|....||.||.||
Worm   399 EGVNCNKCSFGYFRPEGVTWNEPQPCKVCDCDPDKHTGACAEETGKCECLPRFVGEDCDQCASGY 463

  Fly   440 YGYPNCRECECNLNGTNGYHCEAESGQQCPCKINFAGAYCKQCAEGYYGFPE-CKACECNKIGSI 503
            |..|.|:.||||:|||.|..|..|.| |||||..|.|.:|:.||:||..... |..|.|:..||.
Worm   464 YDAPKCKPCECNVNGTIGDVCLPEDG-QCPCKAGFGGTFCETCADGYTNVTAGCVECVCDATGSE 527

  Fly   504 TNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQCICREGFGG 568
            ..:|:.:||:|:|...:.|.:|::|:.|||. ..|.:|:||..|||..:|::.:|||:|:|||.|
Worm   528 HGNCSASTGQCECKPAYAGLSCDKCQVGYFG-DDCKFCNCDPMGTEGGVCDQTTGQCLCKEGFAG 591

  Fly   569 PRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNT-GKCNCLNNFAGKQCTLCTAGYYSYPDCLPC 632
            .:||:|...||.||:||.|.|...|.::..||.| |:|.|..||.|:.|..|.||:|:||||..|
Worm   592 DKCDRCDIAFYGYPNCKACACDGAGITSPECDATSGQCPCNGNFTGRTCDKCAAGFYNYPDCRGC 656

  Fly   633 HCDSHGSQGVSCNSDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGVIDKFAGCGSVPVG 697
            .|...|::|.:|:|:|||.|:.||:|.:||.||..|||||.||:|||:|:||...|.||..|..|
Worm   657 ECLLSGAKGQTCDSNGQCYCKGNFEGERCDRCKPNFYNFPICEECNCNPSGVTRDFQGCDKVSPG 721

  Fly   698 ELCKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKSGQCPCKPHTQGR 762
            |||.|::.||||||::|||.:|:|...:.:||..|||..:||||.|:||..|:|||.||.:..||
Worm   722 ELCSCRKHVTGRICDQCKPTFWDLQYHHEDGCRSCDCNVNGTISGLNTCDLKTGQCMCKKNADGR 786

  Fly   763 RCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPLTTHFFPTL 827
            ||.:|.||.:.|:|.:..||:.|.||:||:.::.||..||||||.||:|||.|.||:..|:||||
Worm   787 RCDQCADGFYRLNSYNQMGCESCHCDIGGALRAECDITSGQCKCRPRVTGLRCDQPIENHYFPTL 851

  Fly   828 HQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFKSSLYRIVLRYVN 892
            ...|||.||........||:..|...|..||.:||.||:.||:.:..:|::.|:::||::.||.|
Worm   852 WHNQYEAEDAHTEDQKPVRFAVDPEQFADFSWRGYAVFSPIQDKILIDVDITKATVYRLLFRYRN 916

  Fly   893 PNAENVTATISVTSDNPL-----EVDQHVKVLLQPTSEPQF--VTVAGPLGVKPSAIVLDPGRYV 950
            |.:..||||:::   ||.     :|:|..|....|...|..  :||.|    ||  .||:||::.
Worm   917 PTSVPVTATVTI---NPRFTHTHDVEQTGKATFAPGDLPAMKEITVDG----KP--FVLNPGKWS 972

  Fly   951 FTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPCELGNME--LCRHYKYASVEVFSPAATPFVI 1013
            ......:.:.|||.|:|||.|||..:|.:....||...:.:  .|....|..:    |:.:...:
Worm   973 LAISTKQRLFLDYVVVLPAEYYEGTVLRQRAPQPCLSHSTKNTTCVDLIYPPI----PSVSRQFV 1033

  Fly  1014 GENSKPTNPVE---TYTDPEHLQIVSHVGDI--PVLSGSQNELHYIV----DVPRSGRYIFVIDY 1069
            ..:..|.|.:.   |.|..||:.:...:.:|  |......:|...:|    |||.:|.|:.|::|
Worm  1034 DMDKVPFNYINEDGTTTALEHVPVEILLSEITGPAAFVRADENPRVVEAKLDVPETGEYVIVLEY 1098

  Fly  1070 ISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICRTSVNEDGMEKSFYINKEDLQPVIISAD 1134
            .:......:..:.:...|......:.:::.|.|:|.||..|:.:|......:.|.:   ..:..:
Worm  1099 HNREETDGNIGVGISQNDKEVLNGNAVIHHCPYATFCRELVSSEGTIPYIPLEKGE---ATVRLN 1160

  Fly  1135 IEDGSRFPIISVTAIPVDQWSIDYINPSPVCVIHDQQCATPKFRSVPDSKKIEFE--TDHEDRIA 1197
            |:....|.:..|..|....:|.:|:...|||:..|.:|....:....||...|.|  ::.:..|.
Worm  1161 IKPNHEFGLAGVQLIKKSDFSSEYLQQVPVCIKKDARCVQQSYPPAADSVTTEAESGSNMDKSIL 1225

  Fly  1198 TNKPPY-ASLDERVKLVHLDSQNEATIVIESKVDATKPNLFVILVKYYQPSHPKYQV-------- 1253
            .:|.|: .|..:.:::|.||.. :||:.| |.|..|:.: ::.:|.|:.|.:....:
Worm  1226 GDKLPFPVSNSKEMRVVPLDDA-QATVEI-SGVVPTRGH-YMFMVHYFNPDNTPINIDVLIQNEH 1287

  Fly  1254 YY-----TLTAGKNQYDGKF------DIQHCPSSSGCRGVIRPAGEG---SFEIDDEFKFTITTD 1304
            |:     ...|..|:|..:|      .:..|||.||||.:||.....   .|.:||::..|...:
Worm  1288 YFQGDSCNSFACYNKYSSRFIFNASVPLAFCPSISGCRALIRDKERPEVIQFYMDDKYTATFYHN 1352

  Fly  1305 RSQS--VWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHF-HITHNASDFCKKSVFSLTA 1366
            .||.  :::|.:..||...|.|.|:.....|.:.||::.|..|:. :...:.|||||:.:||||.
Worm  1353 SSQKGPIYIDSITAVPYNSYKDKLMEPLALDLSNEFLKECSEDNLKNHPESVSDFCKQKIFSLTT 1417

  Fly  1367 DYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFPDCKPCKCPNSAMCEP 1431
            |:|:.||.|:|...||.||:|..:||||:|||.||.|.|..|...||.||:|..|:|.....|:.
Worm  1418 DFNAAALSCDCVAQGSESFQCEQYGGQCKCKPGVIGRRCERCAPGYYNFPECIKCQCNAGQQCDE 1482

  Fly  1432 TTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIANGNSQCDLFNGTCECRQNIEGR 1496
            .||:|.|||:|.|..|::|..|.:|:..:|||::|.|:|.|...||..||..:|.|.||:::.||
Worm  1483 RTGQCFCPPHVEGQTCDRCVSNAFGYDPLIGCQKCGCHPQGSEGGNLVCDPESGQCLCRESMGGR 1547

  Fly  1497 ACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGRDCDQCVDGTYNLQESNPDG 1561
            .||.|..|::.||||..|||::.||..|:||..:..|.||:||.|..|:.|..||::|...||.|
Worm  1548 QCDRCLAGFYGFPHCYGCSCNRAGTTEEICDATNAQCKCKENVYGGRCEACKAGTFDLSAENPLG 1612

  Fly  1562 CTTCFCFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEESIKFDMWPVPADEILLNETTLKADFT 1626
            |..|||||.|..|.|:   :|.|:::             |:....:....|..:::.......:|
Worm  1613 CVNCFCFGVTDSCRSS---MYPVTIM-------------SVDMSSFLTTDDNGMVDNKDDTVIYT 1661

  Fly  1627 LREVNDERPAYFGVLDYLLNQNNHISAYGGDLAYTLHFTSGFDGKYIVA-PDVILFSEHNALVHT 1690
            ..|.: ....||.|   .:.:.::.::||..|.:.|........|.:.| .||.|...:..:.:.
Worm  1662 SEETS-PNSVYFNV---PIEKKDYTTSYGLKLTFKLSTVPRGGRKSMNADADVRLTGANMTIEYW 1722

  Fly  1691 SYEQPSR-NEPFTNRVNIVESNFQTISGKPVSRADFMMVLRDLKVIFIRANYWEQTLVTHLSDVY 1754
            :.|||:. .|.||.:..:|..||.|..||.|:|.:.|.||..|:.|.::|:|::....:.|.:..
Worm  1723 ASEQPTNPEEQFTVKCKLVPENFLTAEGKTVTREELMKVLHSLQNITLKASYFDHPKTSTLYEFG 1787

  Fly  1755 LTLADED-ADGTGEYQFLAVERCSCPPGYSGHSCEDCAPGYYRDPSGPYGGYCIPCECNGHSETC 1818
            |.:::.: .|..  .:..:||:|.||..|:|.||:.||.||:|..||.:.|.|:||||||||.||
Worm  1788 LEISEPNGVDSV--IKASSVEQCQCPAPYTGPSCQLCASGYHRVQSGSFLGACVPCECNGHSATC 1850

  Fly  1819 DCATGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCMICACPLPFDSNNFATSCEISESGDQI 1883
            |..||||:.|:|.|.|||||.|..|:|||||||:|.|||.||||.. .:||||.||::||.|..:
Worm  1851 DPDTGICTDCEHNTNGDHCEFCNEGHYGNATNGSPYDCMACACPFA-PTNNFAKSCDVSEEGQLL 1914

  Fly  1884 HCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSGNINPEDQGSCDTRTGECLRCLNNTFGA 1948
            .|.|||||||.||:.||:||:|.|:..|:.|.||:|:||.|..|..||...:|:|..|..||.|.
Worm  1915 QCNCKPGYTGDRCDRCASGFFGHPQISGESCSPCQCNGNNNLTDSRSCHPNSGDCYLCEQNTDGR 1979

  Fly  1949 ACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDPFVGVCTCHENVIGDRCDRCKPDHYGFESGVG 2013
            .|..||..|||||:..|||.||:|...|:|.||...|.|.|..||.||.||||||||:||....|
Worm  1980 HCESCAAWFYGDAVTAKNCSSCECSQCGSQYCDNKSGGCECKINVEGDSCDRCKPDHWGFSKCQG 2044

  Fly  2014 CRACDCGAASNSTQCDPHTGHCACKSGVTGRQCDRCAVDHWKYEKDGCTPCNCNQGYSRGFGCNP 2078
            |:.|.||.|:.:|||:...|.|.|:.|.||.:|:.|...:|.|.:.||..|:|....|.|..|:.
Worm  2045 CQGCHCGTAAFNTQCNVENGQCTCRPGATGMRCEHCEHGYWNYGEHGCDKCDCEADLSMGTVCDV 2109

  Fly  2079 NTGKCQCLPGVIGDRCDACPNRWVLIKDEGCQECNNCHHALLDVTDRMRYQIDSVLEDFNSVTLA 2143
            .||:|.|..|..|.|||.|...::.|...||:.|:.|.|.|:...|.:..:||.:.....:::.|
Worm  2110 RTGQCHCQEGATGSRCDQCLPSYLRIPTYGCRRCDECVHHLIGDVDNLELEIDVLGTAIANISSA 2174

  Fly  2144 FFTSQKLNYYDQLADELEPKVKLLDPNSVDLSPSKKANSELES---------DAKSYAKQVNQTL 2199
            .....:|         ...|.:..|.|.:    :|..|.|..|         |..:.:.|:...|
Worm  2175 TIVGARL---------ARNKKEFNDINEI----TKMLNDEENSFGNVFGDAQDILTNSTQIQNKL 2226

  Fly  2200 ANAFDIRERSSTTLGNITV----AYDEAVKSADQAKEAIASVEALSKNLEAAASTK---ID-AAL 2256
            .......:.|.::..|||:    ...|.:|.|.:|::::.|:..::  |...:|:|   :| ..|
Worm  2227 VRTKTHSQNSVSSAKNITLNGTEFLQEVMKRAQRARQSVRSLAEIA--LAIGSSSKAVNVDPRLL 2289

  Fly  2257 EQAQHILGQINGTSIELTPNE------QVLEKARKLYEEVNTLVLPIKAQNKSLNALKNDIGEFS 2315
            ::|:..|..:...|.:..|.:      ::.|..:|:.||...|    ..|.::..|.|....|.:
Worm  2290 KEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKL----DKQKETFEAQKKRAEELA 2350

  Fly  2316 DHLEDLFNWSEASQAKSADVERRNVANQKAFDNSKFD------TVSEQKLQAEKNIKDAGNFLIN 2374
            .:|.......:.|::| || :..|:|  |....:|.:      |...::::|.|......|..|
Worm  2351 AYLNSAQQLLKESKSK-AD-KSNNIA--KMLQLTKVENLVAAITDDLERVEAAKGEFQKLNVAI- 2410

  Fly  2375 GDLTLNQINQKLDNLRDALNELNSFNKNVDEELP-----VREDQHKEADALTDQAEQKAAELAIK 2434
            |::|.| :..|.:.:..|:..||....:|.|.|.     ||.|: |..|.....|  ||.||.::
Worm  2411 GNITEN-LKDKREEMTHAVTTLNETRNDVAEALEAAKKRVRRDE-KSVDMQLVNA--KAHELHLQ 2471

  Fly  2435 AQDLAAQYTDMTASAEPAIKAATAYSGIVEAVEAAQKLSQDAISAAG----------NATDK--T 2487
            |..|...:.:...:.:.|::||.|:|.:.:.::.|:....:|..|..          ||.||  .
Worm  2472 ATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSAEPAFAESVQNARDKPFP 2536

  Fly  2488 DGIEERAH-LADTGSTDL-----LQRARQSLQKVQDDLEPRLNASAGKVQKISA-VNNATEHQLK 2545
            |..:|:.. |:.|.|.||     |::..:.|.::.:.|..|..|....:.|.|. ..::.:.:::
Worm  2537 DETKEKIDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQ 2601

  Fly  2546 DINKLIDQLPAESQRDMWKNSNANASDALEILKNVLEILEPVSVQTPKELEKAHGINRDLDLTNK 2610
            ::.||..::.|..:....|.|        ||.....||           .|||:.....:.|..:
Worm  2602 EVEKLKAEIDANIEETRAKIS--------EIAGKAEEI-----------TEKANSAMEGIRLARR 2647

  Fly  2611 DVSQANKQLDDVEGSVSKLSELAEDIEEQQHRVGSQSRQLGQEIENLKAQVEAARQLANSIKVGV 2675
            :..|.||....:   |||..||.:....:..:|.|.|.::.|    :|..:..||..||.||:|.
Worm  2648 NSVQLNKLAPVI---VSKFEELKKLSSARSAKVDSVSDKVSQ----IKEMIAVARDAANRIKLGA 2705

  Fly  2676 NFKPSTILELKTPEKTKLLATRTNLSTYFRTTEPSGFLLYLGND----NKTAQKNNDFVAVEIVN 2736
            :|:..:.|:|..|::....|...::|.||||.:..|..|:.||:    ...|....|:||.||..
Worm  2706 HFEKGSSLDLNIPQRVTRSAAHADISFYFRTEQEHGIPLFFGNEETAVGSRAVPTADYVAAEIEY 2770

  Fly  2737 GYPILTIDLGNGPERITSDKYVADGRWYQAVVDRMGPNAKLTIREELPNGDVVEHSKSGYLEGSQ 2801
            |.|.:|:|||:.|..:..|..|.||.|.:..::|:|....:|:.:  ||......:||....|::
Worm  2771 GRPKITVDLGDAPAVVKLDTPVNDGLWRRLNIERIGKTVSVTLSK--PNSVETAETKSSVAGGNK 2833

  Fly  2802 NILHVDKN-SRLFVGGYPGISDFNAPPDLTTNSFSGDIEDLKIGDESVGLWNF-VYGDDNDQGAR 2864
            ::|::::. |||||||.|  :......||....|.||||.||:..|.:||||. ..|:.|..||:
Worm  2834 SVLNLNQQISRLFVGGVP--TSARISKDLYNRDFVGDIESLKLHGEPIGLWNSREKGNTNVNGAQ 2896

  Fly  2865 ERDVLLEKKKPVTGLRFKGNGYVQLNATS-NLKSRSSIQFSFKADKDTSNGLLFFYGRDKHYMSI 2928
            ::..:.:....:. :...|.||.....:. |.:..:.|..||..  .:.:|||||.|:||.:|::
Worm  2897 KKPKITDNADELV-VSLDGEGYTSYKPSHWNPRKATKISLSFLT--FSPHGLLFFVGKDKDFMAL 2958

  Fly  2929 EMIDGAIFFNISLGEGGGVQSGSQDRYNDNQWHKVQAERENRNGLLKVDDIVISRTNAPLEADL- 2992
            |:.||.:..::.||.|.|........|||.:||.|...||.::..:.:|    ..|.. ||.|:
Worm  2959 ELSDGGVKLSVDLGSGVGQWITESSNYNDGKWHTVSIVREEKHVKIMID----GETEV-LEGDVP 3018

  Fly  2993 ----ELPKLRRLYFGGHPRRLNTSISLQPNFDGCIDNVVINQGVVDLTEYVTGGGVEEGCSAKFS 3053
                |:.....||.||.|..|:...::.| ..|||.:|.:....|||.......||..||.....
Worm  3019 GKDSEMSVTEFLYIGGTPSGLSVRTTIVP-LRGCIKSVKLGSDNVDLESSHASKGVRSGCPLHSV 3082

  Fly  3054 TVVSYAPHEYGFLRMNNVSSDNN-------LHVVLHFKT---TQPNGVLFYAANHDQSSTIGLSL 3108
            ..||       ||.....:|.||       :.|...|||   .||:.:  :..|.|:.|.:.:|:
Worm  3083 RTVS-------FLSDRTTASFNNATEFSEDVSVTFKFKTRSIRQPSSL--FTVNDDEDSVLSVSI 3138

  Fly  3109 -QDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDD-----VDNKRLGSPQPLILE 3167
             :||:|.:.|......::.....|.:.|.|:::.|:..:|:..||     |..|......|
Worm  3139 NEDGILTVTSGEDIATLELAASPDEKWHYVSIRKTKYIIRIDADDSFSNEVARKHADDSNP---- 3199

  Fly  3168 GGDIFF--AGLPDNYRTPRNALASLAYFVGCISDVTVNEEIINFANSAEKKNGNINGCPPHVLAY 3230
              |..|  |....:..||.        |||||.|||:|.::::|||| |.|..::|||
Worm  3200 --DASFLSAFFGKSGETPS--------FVGCIGDVTLNGKLLDFANS-EIKEISLNGC------- 3246

  Fly  3231 EPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTLPPTTPTTTTTTTTTTTSTTTTSTTTTTT 3295
              ||       .|:|..|..:.|...|....|: :.||......:||||||||:...|.......
Worm  3247 --SL-------SDDENISTTTTAAPKPTDDSDV-AVLPIDEEEESTTTTTTTTTEEPTEEPAEMR 3301

  Fly  3296 TPSPIVIDEEKEIEAKTPQK---------ILTTRPPAKLNLPSDERCKLPEQPNFDVDFTEA-GY 3350
            .| |:.:...|. |:.||.:         :...||        |..|.|||.|.  |.|.:| |:
Worm  3302 DP-PVTVTNAKR-ESSTPFEFPDHFESVDLSPARP--------DGHCSLPEDPM--VQFEDAEGF 3354

  Fly  3351 RFYGLREQRLQINSLPVKVRRHHDIGISFRTERPNGLLIYAGSKQRDDFIAVYLLDGRVTYEIRV 3415
            .|...:..|::.:.||..:.:..:.....|....||::..|.:| |.|.|||.|..|||.:....
Worm  3355 NFGSQQYSRIEYDILPEAIDKSGEFTFKIRPTSDNGIIFIATNK-RTDHIAVMLEHGRVVFTYDT 3418

  Fly  3416 GAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLID--KLEQPGSVDLNAERSAPVLAVELPIYL 3478
            |:. |..|.::..:.||.|||::|.|..:...|::|  ..|..|:.:.|.:    ::..:.|.|:
Worm  3419 GSG-QVIIKSDKSIIDGRWHTIKVSRRGKSAHLIVDDNSYESEGAANQNED----LIETQPPFYV 3478

  Fly  3479 GGVNKFLESEVKNL-TDFKTEVPYFNGCLKNIKFDAMDLETPPEEFGVVPCSEQVERGLFFNNQK 3542
            |||...|....:|| ...:::   |:||:|:.|.:...|:. .:|||...||:..|.|::|....
Worm  3479 GGVPADLAGFARNLVVGVRSQ---FSGCIKDFKLNGKSLDN-GKEFGTEQCSQFSEPGMYFGKDG 3539

  Fly  3543 AFVKIFDHFDVGTEMKISFDFRPRDPNGLLFSVHGKNSYAILELVDNTLYFTVKT---------- 3597
            .:..:...::||....:..:.|||..||:|||| |...|..:|.|:.::..||::
Worm  3540 GYAIVQKDYEVGLTFGLEVEMRPRMKNGILFSV-GVLEYITVEFVNGSIKTTVESGSGGEELWHH 3603

  Fly  3598 -DLKNIVSTNYKLPNNESFCDGKTRNVQAIKSKFVINIAVDFISSNPGVGNEGSVITRTNRPLFL 3661
             |::|            .:|||:.::.:..|.:.::.:||:. .::..:..:......|..||:.
Worm  3604 PDIEN------------QYCDGQWQSFKISKKRNLLTVAVNG-KAHLKILKKAKTDVLTKDPLYF 3655

  Fly  3662 GGHVAFQRAPGIKTKKSFKGCISKVEV---------NQRMINITPNMVVGDIWQGYCP 3710
            ||........||||.|.|.|||..|..         .::.::.....|.||:.:..||
Worm  3656 GGLPEGVTNKGIKTNKPFVGCIRFVSFGLKKDRKIRRKKQVDTERFDVFGDVHRNACP 3713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LanA	NP_476617.1	LamNT	18..271	CDD:214532	127/273 (47%)
		EGF_Lam	272..>314	CDD:238012	24/41 (59%)
		EGF_Lam	332..389	CDD:238012	32/56 (57%)
		EGF_Lam	402..443	CDD:238012	21/40 (53%)
		EGF_Lam	448..491	CDD:238012	23/42 (55%)
		Laminin_EGF	495..543	CDD:278482	17/47 (36%)
		Laminin_EGF	541..589	CDD:278482	25/47 (53%)
		Laminin_EGF	587..634	CDD:278482	22/47 (47%)
		EGF_Lam	631..673	CDD:238012	21/41 (51%)
		Laminin_EGF	677..729	CDD:278482	26/51 (51%)
		Laminin_EGF	732..782	CDD:278482	25/49 (51%)
		EGF_Lam	785..828	CDD:238012	25/42 (60%)
		CBM6-CBM35-CBM36_like	831..966	CDD:271143	48/141 (34%)
		Laminin_EGF	1375..1423	CDD:278482	25/47 (53%)
		EGF_Lam	1420..1457	CDD:238012	14/36 (39%)
		Laminin_EGF	1466..1516	CDD:278482	23/49 (47%)
		Laminin_EGF	1514..1562	CDD:278482	21/47 (45%)
		LamB	1632..1760	CDD:214597	35/129 (27%)
		Laminin_EGF	<1775..1801	CDD:278482	13/25 (52%)
		EGF_Lam	1808..1851	CDD:238012	30/42 (71%)
		EGF_Lam	1859..1907	CDD:214543	28/47 (60%)
		EGF_Lam	1916..1968	CDD:238012	25/51 (49%)
		EGF_Lam	1969..2015	CDD:238012	25/45 (56%)
		EGF_Lam	2016..>2054	CDD:238012	15/37 (41%)
		EGF_Lam	2063..>2097	CDD:238012	14/33 (42%)
		Laminin_I	2129..2385	CDD:283627	58/284 (20%)
		Tar	2278..2662	CDD:223910	97/413 (23%)
		Laminin_II	2566..2700	CDD:283628	34/133 (26%)
		LamG	2674..2843	CDD:238058	58/173 (34%)
		LamG	2878..3029	CDD:238058	48/156 (31%)
		LamG	3078..3205	CDD:214598	38/137 (28%)
		LamG	3349..3512	CDD:238058	47/165 (28%)
		LamG	3535..3689	CDD:238058	42/173 (24%)
epi-1	NP_001294008.1	LamNT	24..296	CDD:214532	127/274 (46%)
		EGF_Lam	297..345	CDD:238012	29/48 (60%)
		Laminin_EGF	427..474	CDD:278482	24/46 (52%)
		EGF_Lam	471..520	CDD:238012	24/49 (49%)
		EGF_Lam	519..564	CDD:214543	16/45 (36%)
		Laminin_EGF	564..612	CDD:278482	25/47 (53%)
		Laminin_EGF	610..658	CDD:278482	22/47 (47%)
		Laminin_EGF	656..703	CDD:278482	25/46 (54%)
		Laminin_EGF	701..753	CDD:278482	26/51 (51%)
		Laminin_EGF	756..806	CDD:278482	25/49 (51%)
		EGF_Lam	808..854	CDD:238012	26/45 (58%)
		CBM6-CBM35-CBM36_like	855..988	CDD:271143	48/141 (34%)
		EGF_Lam	1425..1468	CDD:238012	22/42 (52%)
		EGF_Lam	1472..1515	CDD:238012	17/42 (40%)
		Laminin_EGF	1517..1567	CDD:278482	23/49 (47%)
		Laminin_EGF	1565..1613	CDD:278482	21/47 (45%)
		LamB	1669..1793	CDD:214597	35/126 (28%)
		EGF_Lam	1840..1883	CDD:238012	30/42 (71%)
		Laminin_EGF	1891..1945	CDD:278482	30/54 (56%)
		EGF_Lam	1947..1998	CDD:238012	24/50 (48%)
		EGF_Lam	2001..2045	CDD:214543	23/43 (53%)
		EGF_Lam	2048..2092	CDD:214543	17/43 (40%)
		EGF_Lam	2095..2140	CDD:214543	16/44 (36%)
		Tar	<2145..2378	CDD:223910	53/255 (21%)
		BAR	2289..2486	CDD:299863	50/209 (24%)
		Apolipoprotein	2289..2472	CDD:279749	48/195 (25%)
		COG1340	2414..2690	CDD:224259	73/305 (24%)
		ApoLp-III_like	2510..2635	CDD:304399	30/143 (21%)
		Laminin_II	2589..2730	CDD:283628	39/166 (23%)
		LamG	2704..2875	CDD:238058	59/174 (34%)
		LamG	2909..3057	CDD:238058	48/156 (31%)
		LamG	3353..3510	CDD:238058	47/165 (28%)
		LamG	3532..3682	CDD:238058	42/163 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167994
Domainoid	1	1.000	248	1.000	Domainoid score	I1180
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4060
Inparanoid	1	1.050	2038	1.000	Inparanoid score	I16
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45870
OrthoDB	1	1.010	-	-		D1919at33208
OrthoFinder	1	1.000	-	-		FOG0003375
OrthoInspector	1	1.000	-	-		oto20403
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	1	1.000	-	-		X3259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.940