DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LanA and lama5

DIOPT Version :9

Sequence 1:	NP_476617.1	Gene:	LanA / 38723	FlyBaseID:	FBgn0002526	Length:	3712	Species:	Drosophila melanogaster
Sequence 2:	XP_012808101.2	Gene:	lama5 / 100145762	XenbaseID:	XB-GENE-1007923	Length:	3675	Species:	Xenopus tropicalis

Alignment Length:	3964	Identity:	1249/3964 - (31%)
Similarity:	1901/3964 - (47%)	Gaps:	565/3964 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLVILAISYCQA---------ELTPPYFNLATGRKIYATATCGQDTDG---PELYCKLVGANTEH 63
            |||.|.:...|.         .|.|||||||.|.:|.|:||||:..||   .:|||||||.....
Frog    11 LLVPLGLVLAQELPTNGVNGFSLHPPYFNLAEGTRISASATCGEGPDGRPMEDLYCKLVGGPVSG 75

  Fly    64 DHIDYSVIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEVNLTINFEQEFHVA 128
            |  ....||||.||.|.....|::||..|||||||.||||||||||.::|:||:|:...|.||||
Frog    76 D--PSQTIQGQYCDICMANNREKSHPISNAIDGTERWWQSPPLSRGFEYNQVNVTLELGQVFHVA 138

  Fly   129 YLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPITRDDDVICTTEYS 193
            |:.|:..|||||.||.||:|||:|.|:.|||:|:.:..||...||..|.:.|:|||||:||||:|
Frog   139 YVLIKFANSPRPDLWVLERSTDFGVTYQPWQYFASSKRDCLERFGPQTLQRISRDDDVVCTTEHS 203

  Fly   194 KIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGHLMSVARQDPTVTR 258
            :|||||||||.|.|:|:||.:.|:..|.:|..:|:||.||:|.|||..||||||....:||||||
Frog   204 RIVPLENGEIVVSLVNKRPGAMNFSYSPLLMNFTKATTVRLRFLRTNTLLGHLMGKTLRDPTVTR 268

  Fly   259 RYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNECCPGFEQKKWRQNT 323
            ||:||||||||||||:|||||:.|..|||.:|.| |.|.|||:|||..|:.||||:.|..|:..|
Frog   269 RYYYSIKDISIGGRCVCNGHAEVCGAKDPTNPYR-LHCDCQHNTCGTSCDTCCPGYHQLPWKPAT 332

  Fly   324 NARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTVGINCNKCKPKYYR 388
            ......||||||:||:.:|.||.||.|:..|:|.||.:.|||||.:|||||.|:||.:|...||:
Frog   333 KDNANECEPCNCNGHAYDCYYDPEVERRRASMDQHGDFVGGGVCVDCQHNTDGVNCERCIVGYYK 397

  Fly   389 PKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYYGYPNCR------- 446
            ......:....|..|.||..|..|.||:.||.|.|:..:...:|:|||.||..:|.|.
Frog   398 SPDHPSDSPHTCLRCSCDSEFMDGSCEDLTGRCYCKPNYTGETCESCAEGYMDFPLCYPVPDTPN 462

  Fly   447 ---------------ECECNLNGTNGYHCEAES--GQQCPCKINFAGAYCKQCAEGYYGFPECKA 494
                           .|:|::.||.|..|..:.  | .|.||.|:.|..|:.||.|::| |.|..
Frog   463 GGGTGEQVLTVGEIINCDCHVAGTEGNACRKDPFVG-ACVCKPNYRGDSCETCAPGFFG-PSCLD 525

  Fly   495 CECNKIGSITNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQ 559
            |:|:..|.:...|:..:|:|:|.:.|.|..|::|..|:||||.|..|.|...||..:.|: .:|:
Frog   526 CQCSGPGVLDGTCDRESGQCQCRSGFEGFLCDQCAPGFFNYPLCQLCGCSPVGTLPQGCD-STGR 589

  Fly   560 CICREGFGGPRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTLCTAGYY 624
            |:|:..:.||||:||:.|:::||.|:.|:|...|::...|..||.|.|..|:||..|:.|.||:|
Frog   590 CLCKPEYDGPRCEQCIMGYHSYPHCQACSCDPRGAADNNCTPTGHCQCHPNYAGPSCSQCAAGHY 654

  Fly   625 SYPDCLPCHCDSHGSQGVSCN-SDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGVIDKF 688
            .||.|.||||.:.||...:|| ..|||||:.:..|.:||||..|.|.||.|:...|:|
Frog   655 GYPSCTPCHCSAEGSLRNTCNPQSGQCLCRHSITGLRCDSCAPGTYGFPDCQVGPCNP------- 712

  Fly   689 AGCGSVPVGEL---CKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKS 750
            :|..|:.|..|   |:|::.|.|..|::||||||||...|..||..|.|.:||||:.:..|...:
Frog   713 SGSKSLSVNSLEGSCECRDHVEGPACDKCKPLYWNLAPENPHGCTRCQCGSDGTINGVGECRQAT 777

  Fly   751 GQCPCKPHTQGRRCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLAC 815
            |||.|||:...|.|..|:||.::|..:|.|||:.|.||:|||....|.:.:|.|:|...:.|..|
Frog   778 GQCFCKPNICSRTCSTCKDGYYNLQPSSYFGCQGCQCDIGGSIGLACHEKTGGCQCRENVQGSQC 842

  Fly   816 TQPLTTHFFPTLHQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFK 880
            .||...|:||.||..:||.|||....|..||:.|:...|..||.:||...:..|..|...:||..
Frog   843 NQPTPGHYFPDLHHLRYEVEDGVTEDGRPVRFGYNPLEFENFSWRGYAQMSPFQPKVVLTINVTS 907

  Fly   881 SSLYRIVLRYVNPNAENVTATISVTSDNPLEV-----DQHVKVLLQPTSEPQFVTVAGPLGVKPS 940
            ..|:|:|.|:||..|::|...:|...:.....     :|..:::..|::||.||||  |......
Frog   908 PDLFRVVFRFVNRGADSVHGKVSFIEERKFNACANCSEQTKRIVFPPSTEPAFVTV--PQSSFGE 970

  Fly   941 AIVLDPGRYVFTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPCELG-----NMELCRHYKYAS 1000
            ..||:|..:....:. :||:|||.||||:|||||.||...::..|...     |.:.|..|||..
Frog   971 PFVLNPNVWSVVIEV-ENVLLDYLVLLPSAYYEAPILQVKVTEACTYSPTPEQNSKNCLLYKYLP 1034

  Fly  1001 VEVFSPAATPFVIG--ENSKPTNPVETYTDPEHLQIVSHVGDIPVLS---GSQNELHYIVDVPRS 1060
            ::.||.:.....|.  :||.|......:..|.|          |.::   |:..::.:.:.||..
Frog  1035 LDGFSASGGSDGICRLDNSLPRPCQLEHITPRH----------PPMAMCYGNDVDVQFRMAVPHP 1089

  Fly  1061 GRYIFVIDYISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICR-TSVNEDGMEKSFYINKE 1124
            |||:.:::|.::....:: .|.:....:...:.:...|||.||.:|| .::::.....:|.:..|
Frog  1090 GRYVVLVEYANEEEVQNT-IITVNSPPHRPQQGTFAFYPCKYSFLCRGVALDQHHRVATFDLTTE 1153

  Fly  1125 DLQPVIISADIEDGSRFPIISVTAIPVDQWSIDYINPSPVCVI-------HDQQCATPKFR---- 1178
              ..:..||   |.:.|.:..|..||.:|:|::|::|...|:.       ....|...:|:
Frog  1154 --ATIRFSA---DRTHFYLSKVYLIPAEQFSMEYVSPRVHCIATHGTFSPSSGSCVPSRFQKPSQ 1213

  Fly  1179 ------------------------SVPDSKKIEFETDHEDRIATNKPPYASLDERVKLVHLDSQN 1219
                                    |.||.:.:..:.:       ..||.|.  :..:||||   :
Frog  1214 SVVLSEGRTGSIPNNIPLSQGFVPSSPDGQAVPSQPE-------TLPPTAV--DSTRLVHL---H 1266

  Fly  1220 EATIVIESKVDATKPNLFVILVKYYQPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRGVIR 1284
            ....|:........|..:..:|.||||||..:.:...:..|: .:.|..:...||...|||.::.
Frog  1267 PVQSVVGYNGQVQSPGRYAFIVHYYQPSHQTFAIEVRVQGGR-VWQGSANATFCPHGYGCRSLVV 1330

  Fly  1285 PAGEGSFEI-DDEFKFTITTDRSQSVWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFH 1348
            ...:...:: |:.|..||.....:.||::|::|:|...|:...||||..|::..||..||.:.|.
Frog  1331 SENQVVLDVTDNNFSVTIRVPDGRIVWIEYVLVIPEDSYSSSYLVEEPLDKSYHFISQCGANSFQ 1395

  Fly  1349 ITHNASDFCKKSVFSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYY 1413
            .....|.||:.:..||:..||:||.||:|..||:....|.|.||||.|:||||.|.|..|.:.|:
Frog  1396 SNPANSKFCRDAAISLSLFYNNGAQPCDCHEAGALGTACEPHGGQCNCRPNVIGRDCSRCATGYW 1460

  Fly  1414 GFPDCKPCKCPNSAMCEPTTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIANGNS 1478
            |||:|:||.| .|.:|:..||:|:|||..|...|..|.|..:|.|.::|||||.|:|.|:.|...
Frog  1461 GFPNCRPCDC-GSRLCDEVTGQCICPPRTIKPDCVVCQPQAFGCHPLVGCEECNCSPTGLQNKTE 1524

  Fly  1479 Q-CDLFNGTCECRQNIEGRACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGR 1542
            . ||:..|.|.|..|:.||.|:.|:.|::.:|.|..|:|::.|.||.:||.:.|.|.||:||.|.
Frog  1525 PGCDIQTGQCTCMPNVVGRRCERCAPGFYGYPACRPCNCNRDGVELSICDPVTGQCHCKENVEGL 1589

  Fly  1543 DCDQCVDGTYNLQESNPDGCTTCFCFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEESIKFDMW 1607
            .||.|..||:.|..:||.|||.|||||.|.||.:|         .||    ..||.:    .:.|
Frog  1590 TCDHCRLGTFYLDAANPKGCTRCFCFGATDRCHTA---------SKH----RAEFSD----MNGW 1637

  Fly  1608 P-VPAD----EILLNETTLKADFTLREVNDERPAYF--GVLDYLLNQNNHISAYGGDLAYTLHFT 1665
            . |..|    ||.:.......|..|.:|.|....::  ....||   .:.:|:|||.|.|.||..
Frog  1638 VLVGGDRQEVEISVRPEEGLVDANLEDVPDVYQEFYWHAPRSYL---GDRVSSYGGFLRYELHSK 1699

  Fly  1666 S--GFDGKYIV--APDVILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNF---QTISGKPVSRA 1723
            :  |......|  .||:||.....::.|.....|...|.:..|:::||.||   ||.:  ||||.
Frog  1700 AIRGDQPNIPVERRPDIILKGNQMSIAHLQTRYPMSGEHYHGRIHLVEGNFVHVQTYN--PVSRE 1762

  Fly  1724 DFMMVLRDLKVIFIRANYWEQTLVTHLSDVYLTLADEDADGTGEYQFLAVERCSCPPGYSGHSCE 1788
            :.||||.:|:.:.|||...:.:....|..|:|.:..|.:.|....:   ||.|.||..|.|.||:
Frog  1763 ELMMVLANLEQLLIRALNSQSSSSVSLRRVFLDIGHESSVGVRAPE---VELCMCPANYLGDSCQ 1824

  Fly  1789 DCAPGYYRDPSGPYGGYCIPCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNATNGTP 1853
            :||||||||..|.:.|.|:||.|.|||:.|...||.|.||||.||||.||||..|:..|.|....
Frog  1825 ECAPGYYRDTKGLFLGKCVPCNCGGHSDQCLPGTGACVKCQHNTEGDRCERCKDGFVSNGTVDGS 1889

  Fly  1854 GDCMICACPLPFDSNNFATSCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCE 1918
            ..|:.|.|||...|||||..|  .:.|....|.|:.||.|..||.||.||||.|..||..||||:
Frog  1890 LQCVSCPCPLSVPSNNFAIGC--FQRGSTFQCLCRLGYAGANCERCAPGFYGNPMVIGSSCKPCD 1952

  Fly  1919 CSGNINPEDQGS-CDTRTGECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDP 1982
            |:||.:.....| ||...|.|..|:.||.|..|.:|||||||||::.|||..|||...|||:||.
Frog  1953 CNGNTDSNMLFSDCDPLFGTCSSCMFNTAGTHCEVCAPGFYGDAVRAKNCTRCDCSPCGTQSCDS 2017

  Fly  1983 FVGVCTCHENVIGDRCDRCKPDHYGFESGVGCRACDCGAASNSTQCDPHTGHCACKSGVTGRQCD 2047
            ..|.|:|...|.|.|||||:..:||:....||..|.|.|.|.|.:|||.:|.|.|..|:||.||.
Frog  2018 RTGRCSCRPGVTGSRCDRCEEGYYGYNGCSGCHKCSCAAGSASARCDPVSGQCLCLPGITGAQCQ 2082

  Fly  2048 RCAVDHWKYEKDGCTPCNCNQGYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRWVLIKDEG---- 2108
            :||..:|.:...|||.|:|     :|..|:|.||:|||..|:.|.:||.|..::.:....|
Frog  2083 QCAPGYWGFSPSGCTKCHC-----KGGSCDPRTGECQCSDGLTGKQCDTCSRQYEIPVSHGPDIL 2142

  Fly  2109 -CQECNNCHHALLDVTDRMRYQIDSV---LEDFNSVTLAFFTSQKLN-----------YYDQLAD 2158
             |:.|::|...||:..||..:.:..:   |.:.:...:|:.....||           .|....:
Frog  2143 KCEPCDSCVVTLLEDLDRNGHFLPGIGDQLANLSVSAIAWNHLSALNTSIANLTELWLQYQGTIN 2207

  Fly  2159 ELEPKVKLLDPNSVDLSPSKKANSELESDAKSYAKQVNQTLANAFDIRERSST------------ 2211
            .::.|...::.:|:.|:          .|..:...:||.|...|..::..:..
Frog  2208 GIKDKADDMEDHSISLA----------QDLDALQDKVNMTNRTAISVQRATKNTHQRAGDLLNKV 2262

  Fly  2212 -TLGNITVAYDEAVK-----------SADQAKEAIASVEALSKNLEAAASTKIDAALEQAQHILG 2264
             ||.|:|....|.:|           |.::.:..::.||.:.:.|.|       ...:...|:
Frog  2263 QTLCNVTQGMVEQLKKIGSSSSSNVTSTEEFRRIMSEVERMMRELRA-------RDFQHPSHL-- 2318

  Fly  2265 QINGTSIELTPNEQVLEKARKLYEEVNTLVLPIKAQ--------NKSLNALKNDIGEFSDHLEDL 2321
                              |||.|.|...|:..:||:        .:.|:..|..:..:|..:.||
Frog  2319 ------------------ARKEYNESIKLLNRVKAELVSSQQTNQELLSETKRRLDTYSSEVMDL 2365

  Fly  2322 FNWSEASQAKSADVERRNVANQKAFDN--SKFDTVSEQKLQAEKNIKDAGNFLIN-GDLTLNQIN 2383
            .:....:..|:...|..|..||...:.  .|...:.:|..:....||.|.:.|:. .||.....|
Frog  2366 RDALNEAVNKTRQTEDLNSINQNTLEEYLLKVSDLKKQHSELVSAIKMAEDALVQVSDLLQTMEN 2430

  Fly  2384 QK---------LDNLRDALNELNSFNKNVDEELPVREDQHKEADALTDQAEQKAAELAIKAQDLA 2439
            .|         ||..|.:|.|..........::|:           .::||..|.:|...|:.|.
Frog  2431 LKEEYEKLAAGLDGARGSLIEKGKKFSPASSKIPI-----------VEKAEMHAKDLGQLAKALF 2484

  Fly  2440 AQYTDMTASA--EPAIKAATAYSGIVEAVEAAQKLSQDAISAAGNATDK--TDGIEERAHLADTG 2500
            :...|.....  :.||.|:.|||.|::||:.|:|.:::|...||:|...  .:.:.::.......
Frog  2485 SAIGDANQDGYIQKAINASDAYSTIIDAVKQAEKAAKEASRVAGDAVKNILNEELGKKGKELKQK 2549

  Fly  2501 STDLLQRARQSLQKVQDDLEPRLNASAGKVQKISAVNNATEHQLK-DINKLIDQ--LPAESQRDM 2562
            |:.|...||.:..::..|::.:|..:..|:||    |.|.:.::| |:..::|:  :..::..|.
Frog  2550 SSQLGDSARAAEDELSQDVQSKLQEAKTKLQK----NKANKEKVKADLQSIMDKISMTRDNVTDD 2610

  Fly  2563 WKNSNANASDALEILKNVLEILEPVSVQTPKELE---KAHGINRDLDLTNKDVSQANKQ----LD 2620
            ..::...|::|.:....|.:.|    :...|.||   :.:|     :|.|:|||:|.::    :.
Frog  2611 ITSAKFKAAEANDTANRVEDSL----IDIKKNLESWKEKYG-----NLQNEDVSEAIEEAKTSVS 2666

  Fly  2621 DVEGSVSKLSELAEDIEEQQHRVGSQSRQLGQEIENLKAQVEAARQLANSIKVGVNFKPSTILEL 2685
            |:..::..|.:....:|.:|    :|:..:...|..::..:..||..|:.:||.|.|..|:.:::
Frog  2667 DLVNTIPLLLDKVNQLENRQ----TQNNSISDSISRIRELISQARDAASKVKVPVKFNGSSGVQM 2727

  Fly  2686 KTPEKTKLLATRTNLSTYFRTTEPS-----------GFLLYLGNDNKTAQKNNDFVAVEIVNGYP 2739
            :||.....||..|:|..:.:..||:           .|:|:||:.:.|    .|::.: ::.|..
Frog  2728 RTPSNVPDLAAYTSLKLHIQNPEPTKKKRQADTEQGRFVLFLGHKDGT----GDYLGL-VLKGNK 2787

  Fly  2740 ILTI-DLGN-GPERITSDKYVADGRWYQAVVDRMGPNAKLTIREELPNGDVVEHSK-SGYLEGSQ 2801
            :..: .||: .|..:::::.:.: .:....|:|:....:::|   ....|.:...| .....|.|
Frog  2788 LQCVYKLGDEEPTFLSANEDIRE-EFVTVAVERILQYGQMSI---FVTKDTLHEIKGDSTASGEQ 2848

  Fly  2802 NILHVDKNSRLF-VGGYPGISDFNAPPDLTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGARE 2865
            .:|:::....:| |||||  :||..|..|...|:.|.||...:.::.:.|::|       :...|
Frog  2849 GLLNLNPEQVVFYVGGYP--ADFTPPAPLNYPSYRGCIEMDTLNEKPISLYDF-------EQTFE 2904

  Fly  2866 RDVLLEKKKP------------VTGLRFKGNGYVQLNATSNLKSRSSIQFSFKADKDTSNGLLFF 2918
            .|.  :|:||            ..|..|.|.||.::...:  ...||.:|...|...:.||:||:
Frog  2905 LDT--KKEKPCARSKSTGDPWLTEGSYFDGTGYAEVKLET--LPGSSKRFELDARLVSYNGILFY 2965

  Fly  2919 YGRDKHYMSIEMIDG--AIFFNISLGEGGGVQSGSQDRYNDNQWHKVQAERENRNGLLKVDDIVI 2981
            ...:..::|:.:.||  |:|::|    |.|:|.......|     |:|..    :...||..:::
Frog  2966 LDAEDQFLSLAVQDGKLALFYDI----GDGLQVSKPMEPN-----KLQIS----SSTPKVVQVIL 3017

  Fly  2982 S-------------RTNAPLEADLE---LPKLRRLYFGGHP--RRLNTSISLQP---NFDGCIDN 3025
            :             |.|. ...|.:   |...:..:.||.|  :...:.::|.|   :..||:..
Frog  3018 AVVGGKKKIIVRLERVNV-YNVDYDKGSLETAQYFFLGGLPSSKMPESLVALFPGGGSIRGCMKG 3081

  Fly  3026 VVINQGVVDLTEYVTGGGVEEGCSAKFSTVVSYAPHEYGFLRM--NNVSSDNNLHVVLHFKTTQP 3088
            :......|||....| .||..||::......|...:.:|:|.|  .||.|.||.:....|:|:||
Frog  3082 IKALGKYVDLKRMST-TGVSYGCTSDLLIARSVQFYGHGYLNMAVKNVPSLNNFYTGFGFRTSQP 3145

  Fly  3089 NGVLFYAANHDQSSTIGLSLQDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDD- 3152
            ||.|:.....:.|..:  ::|.|.|.:..:.:::....:.. ||..|.:|:......:|..|||
Frog  3146 NGFLYQHTTEEGSCQV--AVQHGRLSVKILNAEMRSKTQFA-DGAGHYLTLYSNNDAVRFYVDDK 3207

  Fly  3153 -VDNKRL--GSPQP-----LIL----EGGDIFFAGLPDNYRTPRNALASLAYFVGCISDVTVNEE 3205
             .:.:.|  |:.:|     |:|    :||:|.                   ...||||:|.|
Frog  3208 LQETRTLAAGTGRPDLTSTLLLGGFQDGGEIH-------------------NLTGCISNVFV--- 3250

  Fly  3206 IINFANSAEKKNGNINGCPPHVLAYEPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTLPPT 3270
                    ::|:|     |..||..:                   .|.::|
Frog  3251 --------KRKDG-----PQAVLDLQ-------------------QNQESL-------------- 3269

  Fly  3271 TPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKILTTRPPAKLNLPSDERCKL 3335
                         :.|.:...:....|..|.....|   .|..|| |..|..|......:..|..
Frog  3270 -------------NVTMSCQASMEEQPQEIRSPSRK---GKLKQK-LRQRKLADHKHLEETSCVH 3317

  Fly  3336 PEQPNFDVDFTEAGYRFYGLREQRLQINSLPVKVRRHHDIGISFRTERPNGLLIYAGSKQRDDFI 3400
            |:.       .....||.|.....|:...||...|......:..|....|||:.|...::....:
Frog  3318 PKA-------VRGALRFGGSSSSHLEFTRLPPIFRDRFHFSLEIRLNASNGLIFYGRDERSSSSL 3375

  Fly  3401 AVYLLDGRVTYEIRV-GAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLIDKLEQPGSVDLNAE 3464
            ::|:.:||...::.| |..|  ::.::.:.|||.||||...:.:.|:.|:||.::...||...|.
Frog  3376 SLYVSNGRFVLQLVVLGKSL--RLRSKEKYNDGLWHTVFFGKEKNKLHLVIDGIKAQSSVVYPAV 3438

  Fly  3465 RSAPVLAVELPIYLGGVNKFLESEVKNLTDFKTEVP-----YFNGCLKNIKFDAMDLETPPEEFG 3524
            .|    ::..|:::||:...:.         :.::|     .|:|||||:|.|......|.:..|
Frog  3439 TS----SLTGPVFIGGLPPLIR---------RPDIPDASLNSFHGCLKNLKLDGKAFNPPNKIMG 3490

  Fly  3525 VVPCSEQV-ERGLFFNNQKAFVKIFDHFDVGTEMKISFDFRPRDPNGLLFSVHGKNSYAI-LELV 3587
            |..|.|.: |:|.|| ::..|:|:....|:|..:::..:.||...:||||.|..:..::: |.:.
Frog  3491 VAQCYEGITEQGFFF-SEGGFLKLDHEVDIGQSLEVKLEIRPIHHSGLLFHVGSEGGHSVTLSMA 3554

  Fly  3588 DNTLYFTVKTDLKNIVSTNYKLPNNESFCDGKTRNVQAIKSKFVINIAVDFISSNPGVGNEGSVI 3652
            :..:..:|...... .||:.|.|  :..|||:...|...|...||.:.|| ...|..||...|..
Frog  3555 EGKVSVSVNAGASE-YSTSVKFP--QPLCDGQWHTVAVTKVSNVIQLDVD-TEGNHAVGASQSQP 3615

  Fly  3653 TRTNRPLFLGGHVAFQRAPG-----IKTKKSFKGCISKVEVNQRMINIT-PNMVVGDIWQGYCP 3710
            |.:...|::||      .||     .|....::||:..:.:|::.:::: |...:|......||
Frog  3616 TASTGTLYVGG------VPGNIHSPRKPHTPYQGCMRNLVINRKAVDVSKPGTFIGSASTNVCP 3673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LanA	NP_476617.1	LamNT	18..271	CDD:214532	146/264 (55%)
		EGF_Lam	272..>314	CDD:238012	25/41 (61%)
		EGF_Lam	332..389	CDD:238012	32/56 (57%)
		EGF_Lam	402..443	CDD:238012	17/40 (43%)
		EGF_Lam	448..491	CDD:238012	17/44 (39%)
		Laminin_EGF	495..543	CDD:278482	18/47 (38%)
		Laminin_EGF	541..589	CDD:278482	19/47 (40%)
		Laminin_EGF	587..634	CDD:278482	21/46 (46%)
		EGF_Lam	631..673	CDD:238012	21/42 (50%)
		Laminin_EGF	677..729	CDD:278482	20/54 (37%)
		Laminin_EGF	732..782	CDD:278482	21/49 (43%)
		EGF_Lam	785..828	CDD:238012	17/42 (40%)
		CBM6-CBM35-CBM36_like	831..966	CDD:271143	44/139 (32%)
		Laminin_EGF	1375..1423	CDD:278482	25/47 (53%)
		EGF_Lam	1420..1457	CDD:238012	15/36 (42%)
		Laminin_EGF	1466..1516	CDD:278482	19/50 (38%)
		Laminin_EGF	1514..1562	CDD:278482	22/47 (47%)
		LamB	1632..1760	CDD:214597	42/136 (31%)
		Laminin_EGF	<1775..1801	CDD:278482	15/25 (60%)
		EGF_Lam	1808..1851	CDD:238012	25/42 (60%)
		EGF_Lam	1859..1907	CDD:214543	24/47 (51%)
		EGF_Lam	1916..1968	CDD:238012	26/52 (50%)
		EGF_Lam	1969..2015	CDD:238012	21/45 (47%)
		EGF_Lam	2016..>2054	CDD:238012	18/37 (49%)
		EGF_Lam	2063..>2097	CDD:238012	14/33 (42%)
		Laminin_I	2129..2385	CDD:283627	52/304 (17%)
		Tar	2278..2662	CDD:223910	91/417 (22%)
		Laminin_II	2566..2700	CDD:283628	33/140 (24%)
		LamG	2674..2843	CDD:238058	43/183 (23%)
		LamG	2878..3029	CDD:238058	38/173 (22%)
		LamG	3078..3205	CDD:214598	33/139 (24%)
		LamG	3349..3512	CDD:238058	44/168 (26%)
		LamG	3535..3689	CDD:238058	42/159 (26%)
lama5	XP_012808101.2	Laminin_N	34..281	CDD:395009	144/248 (58%)
		EGF_Lam	282..330	CDD:238012	28/48 (58%)
		Laminin_EGF	342..409	CDD:395007	31/66 (47%)
		EGF_Lam	411..453	CDD:238012	17/41 (41%)
		EGF_Lam	479..526	CDD:214543	19/48 (40%)
		Laminin_EGF	526..574	CDD:395007	18/47 (38%)
		Laminin_EGF	572..619	CDD:395007	19/47 (40%)
		Laminin_EGF	617..664	CDD:395007	21/46 (46%)
		EGF_Lam	661..704	CDD:238012	21/42 (50%)
		Laminin_EGF	710..756	CDD:395007	20/52 (38%)
		EGF_Lam	758..810	CDD:238012	22/51 (43%)
		EGF_Lam	812..855	CDD:238012	17/42 (40%)
		Laminin_EGF	1422..1470	CDD:395007	25/47 (53%)
		Laminin_EGF	1512..1563	CDD:395007	19/50 (38%)
		EGF_Lam	1560..1610	CDD:238012	23/49 (47%)
		Laminin_B	1673..1810	CDD:395006	43/144 (30%)
		VSP	1823..2128	CDD:146106	152/311 (49%)
		Laminin_EGF	2005..2049	CDD:395007	20/43 (47%)
		EGF_Lam	2052..2096	CDD:214543	19/43 (44%)
		Laminin_I	2172..2429	CDD:310534	51/293 (17%)
		PTZ00121	<2291..>2592	CDD:173412	73/342 (21%)
		Laminin_II	2614..2742	CDD:368703	33/140 (24%)
		LamG	2760..2892	CDD:214598	32/142 (23%)
		LamG	2927..3083	CDD:238058	38/171 (22%)
		LamG	3112..3250	CDD:238058	41/159 (26%)
		LamG	3324..3478	CDD:238058	44/168 (26%)
		LamG	3502..3651	CDD:238058	42/159 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	310	1.000	Domainoid score	I1314
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4060
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1919at33208
OrthoFinder	1	1.000	-	-		FOG0003375
OrthoInspector	1	1.000	-	-		otm49392
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040