Protein Alignment CG8219 and Apl

DIOPT Version :9

• Sequence 1: NP_648038.1
• Gene: CG8219 / 38722
• FlyBaseID: FBgn0035693
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_730182.1
• Gene: Apl / 59216
• FlyBaseID: FBgn0042178
• Length: 1080
• Species: Drosophila melanogaster
• Alignment Length: 1051
• Identity: 187/1051 - (17%)
• Similarity: 338/1051 - (32%)
• Gaps: 397/1051 - (37%)

  Fly    16 ILKDSQSPGK---ATQLA-----VQETENEATRSMSGLILKNNIR--MHDITLQPEHLEYIKHQC 70
            :||..::|..   .||:.     |||      |.::.::||..::  .|...:..||...||...
  Fly    27 MLKAYENPDSLLVLTQIVMSDRPVQE------RQVAAVLLKRRVKKLRHWQLVPAEHQAAIKSNM 85

  Fly    71 LQA-VGDSSPEIRGTVGILI-TTIASNIGLHN-W-PQLLPSLCEMLDNQDYNVCE---GAFSALQ 128
            ||. :......::|||..:| :.:....|..| | .::|..:.|...:.|....|   ..||:|.
  Fly    86 LQVLIAVKEKTVKGTVAFIIGSLVRHEEGEQNSWREEILKFIYERCSSPDPIESERGSSIFSSLM 150

  Fly   129 KICEDS------------AGIL------ENMPLNTMIPKFLEYFKHSS--------PKIRSHAIA 167
            ....|.            ||||      .||...|:         |:.        |.:..|:.|
  Fly   151 DAAPDQFSDHTDTMFPLLAGILVTAEANGNMATPTV---------HNMLTGSCFLLPFVSGHSNA 206

  Fly   168 CINQFIINRSQALMLNIDSLIQ-----------NLLDVPSDNDPAVRMNVCHALVGLVGVRIDLM 221
              .|.::.....::..:.:.::           :::|..:::.|       |.|.|.|.:.::..
  Fly   207 --EQIVVKAVPLILKALAAFVEKGYSIEFMGAFDIIDSMAEHVP-------HLLTGNVKLLLEFC 262

  Fly   222 MPHMSQIIELILLRSQDADENVALQATEFWLSLGKQRN----CRDILSPILSQLVPVLVSRTQYT 282
                     |::.|::..|.::.:|...|..||.:.:.    .:.:|.|.||.|..|:.
  Fly   263 ---------LMIARNKQFDASIRVQVLTFVGSLVRLKKKIIMKQKLLQPTLSVLFEVIC------ 312

  Fly   283 ETDIILLKGDVGEDDKEPDRQQDISPRFHMSRVHGISNELDENSDDDMW--DSALNLRKCSACAL 345
                                |.|:                 |..|||.:  :|..:....:|..|
  Fly   313 --------------------QDDL-----------------EEGDDDYFSSESLSSPSNAAAQTL 340

  Fly   346 DIIS-KIFGDVCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITC- 408
            |::: .:..|..:|.:|.:|:.||...|.|::.|..:.:|.|||||.:.:.....|::..:|..
  Fly   341 DLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLNIIKAG 405

  Fly   409 LSDKKPLVRSITCWTFMRFPKWV------------------LNQ---------PHDKY------- 439
            :.|....||:...:...:|.:::                  |||         |..|:
  Fly   406 VLDSVMFVRTAAFFALGQFSEFLQPTICKFAPQILPVLFDYLNQLVLELKVGEPDSKHMDRMFYA 470

  Fly   440 LEPLIEEL-------LKCILD---------SNKRVQEAACSAFVALEEEACTQLVPYLENMLKTF 488
            ||...|.|       |..::|         ::.:::|.|.||..|:...|...|:||...::...
  Fly   471 LETFCENLDEDIVPYLPTLMDRLFGVMEPQNSNQMREMALSAIAAVSAAAKENLMPYFPRIMTVL 535

  Fly   489 VLAFSK------YHQR---------------------------NLLIM---------------YD 505
            .....|      |.||                           |..:|               |:
  Fly   536 QGCLVKDCPKEMYSQRIQAIDTLAALCRELGKDNIIPLADDTMNFCLMMLEDGPDDPEYRRSIYN 600

  Fly   506 VVGLLAESVGHHLNK--PQYIDILMPPLMDKWNLV---------------------------KDD 541
            ::..|:..|...:..  |::||.:|..::...::|                           .:|
  Fly   601 LMSSLSSVVNESMASVFPKFIDRIMESVIFSEDMVPNVSDNADDDLALVDAPDIEIDLEHTDDED 665

  Fly   542 DKDII-----YLLE------CLSSIATALQSSFLPYCDSVYRKGISIIEETINQ------DMMC- 588
            |:|..     |::|      .|...||...::|.||..|.:.....:|:.....      |.:|
  Fly   666 DQDAYPVENDYIVEKEEAILSLKEFATHTGAAFAPYLQSAFENVYKMIDHPQGDVRMACIDSICS 730

  Fly   589 --------------KQSQSTDYPDKERMVIALDLVSGLIEGLQSLIE-----PLVANSKLLQLLC 634
                          |::.....|....::...|.|:.::..|..|.:     |.:.:.:..:|:.
  Fly   731 FITALHKLDDAAGLKRACEIAIPKFAHIMRTDDQVAVVLRMLDVLYDVFKYVPAINSQEHAELIF 795

  Fly   635 QCMGDV----------------------------------------------------------- 640
            .|:.|:
  Fly   796 GCIRDIFTNKMACQFNEESGGGDDECSEESENDEMLFENAANLFPMFGLTLQPELFSLYFGRLYH 860

  Fly   641 -------------MPEVRQSSFALLGD----LSGAC---FSQVYPYTAHFILILVQNLNPSVVGV 685
                         :||.|...:..|.|    |.|.|   |..:.|       |.:.....|....
  Fly   861 FYIQRLAKVKERDLPEQRAYIYGALADCCKALKGCCATYFDALRP-------IFIAGSRDSDAKA 918

  Fly   686 CNNAVWAIGQICVKLGE---ETKPYVRLLLSELMILMNRQDIPKNLSRNAAITLGRLGNACPDEV 747
            ..|:.:|:|:|.....|   |:.|.:...|||.::   |:.:|..:. |....:.||....||.|
  Fly   919 RQNSYFALGEIVFHSEEKSFESYPTILQALSEAIV---RESVPAAMD-NICGAVARLIVTNPDSV 979

  Fly   748 APYLPEFLRQW 758
            .  |.:.|..|
  Fly   980 P--LGQVLPVW 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8219	NP_648038.1	IBN_N	11..76	CDD:281761	18/70 (26%)
		ARM	104..214	CDD:237987	25/149 (17%)
		HEAT repeat	104..132	CDD:293787	7/30 (23%)
		HEAT repeat	145..175	CDD:293787	6/37 (16%)
		HEAT repeat	186..212	CDD:293787	4/36 (11%)
		HEAT repeat	225..254	CDD:293787	5/28 (18%)
		HEAT repeat	360..388	CDD:293787	9/27 (33%)
		HEAT_2	361..465	CDD:290374	32/154 (21%)
		HEAT_EZ	373..424	CDD:290247	13/51 (25%)
		HEAT repeat	400..430	CDD:293787	6/30 (20%)
		HEAT repeat	442..468	CDD:293787	8/41 (20%)
		HEAT repeat	629..657	CDD:293787	9/103 (9%)
		HEAT_EZ	642..696	CDD:290247	15/60 (25%)
		HEAT repeat	667..699	CDD:293787	6/31 (19%)
		HEAT repeat	710..738	CDD:293787	6/27 (22%)
Apl	NP_730182.1	IBN_N	29..90	CDD:197981	17/66 (26%)
		HEAT repeat	356..384	CDD:293787	9/27 (33%)
		HEAT repeat	397..427	CDD:293787	5/29 (17%)
		HEAT repeat	438..473	CDD:293787	6/34 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438716
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10527
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940