Protein Alignment CG8219 and Tnpo

DIOPT Version :10

• Sequence 1: NP_648038.1
• Gene: CG8219 / 38722
• FlyBaseID: FBgn0035693
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_477368.1
• Gene: Tnpo / 38721
• FlyBaseID: FBgn0024921
• Length: 893
• Species: Drosophila melanogaster
• Alignment Length: 893
• Identity: 614/893 - (68%)
• Similarity: 711/893 - (79%)
• Gaps: 42/893 - (4%)

  Fly     1 MAWTPRDEGLQQLLPILKDSQSPGKATQLAVQ-----------------------ETENEATRSM 42
            |.|.|:.|||||::.|||:||||..|||:|||                       :||:|.|||:
  Fly     1 MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMKLEEFNRYPDFNNYLIYVLTKLKTEDEPTRSL 65

  Fly    43 SGLILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILITTIASNIGLHNWPQLLPS 107
            ||||||||||||..|||||.:|||||:|||||||:||.||.||||||||||||.|||||||||||
  Fly    66 SGLILKNNIRMHGTTLQPEIVEYIKHECLQAVGDASPLIRATVGILITTIASNGGLHNWPQLLPS 130

  Fly   108 LCEMLDNQDYNVCEGAFSALQKICEDSAGILE----NMPLNTMIPKFLEYFKHSSPKIRSHAIAC 168
            ||||||||||||||||||||||||||||.||:    |.|||.|||||||||||||||||||||||
  Fly   131 LCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAALNRPLNIMIPKFLEYFKHSSPKIRSHAIAC 195

  Fly   169 INQFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHALVGLVGVRIDLMMPHMSQIIELIL 233
            ||||||||||||||||||.|:||..:.||.|..||.||||.||.|:.||:|.:|||||||||.:|
  Fly   196 INQFIINRSQALMLNIDSFIENLFHLSSDEDHEVRKNVCHGLVMLLEVRMDRLMPHMSQIIEYML 260

  Fly   234 LRSQDADENVALQATEFWLSLGKQRNCRDILSPILSQLVPVLVSRTQYTETDIILLKGDVGEDDK 298
            ||:||.||.|||:|:||||||.:|..|:|:|:|.|:||.||||...:|:|.|||||||:|.|||.
  Fly   261 LRTQDTDEGVALEASEFWLSLAEQSICKDVLAPYLAQLAPVLVRGMRYSEVDIILLKGNVEEDDM 325

  Fly   299 EPDRQQDISPRFHMSRVHGI---------------SNELDENSDDDMWDSALNLRKCSACALDII 348
            .|||::||.||||.||.|.|               .:|.::..|||...|..|||||||.|||::
  Fly   326 VPDREEDIRPRFHKSRAHTIRSTQEGGAGATGDDDDDEFEDGMDDDSSLSEWNLRKCSAAALDVL 390

  Fly   349 SKIFGDVCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITCLSDKK 413
            :.:|.:.|||::||||||.|||||||||||||:||||||||||||:|.||||||||||:||||||
  Fly   391 ANVFREDCLPVVLPILKETLFHQEWVIKESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKK 455

  Fly   414 PLVRSITCWTFMRFPKWVLNQPHDKYLEPLIEELLKCILDSNKRVQEAACSAFVALEEEACTQLV 478
            .|||||||||..|:..||:|||||:||:||:|||||.||||||||||||||||..|||||||:||
  Fly   456 ALVRSITCWTLSRYANWVVNQPHDQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELV 520

  Fly   479 PYLENMLKTFVLAFSKYHQRNLLIMYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDK 543
            ||||.:|||.|.|||||..:||||:||.||.||:|||||||||||||||||||:|||||:|||||
  Fly   521 PYLEYILKTLVFAFSKYQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDK 585

  Fly   544 DIIYLLECLSSIATALQSSFLPYCDSVYRKGISIIEETINQDMMCKQSQSTDYPDKERMVIALDL 608
            |:..||||||||||||||.||||||.|||:.||:||:||||:|:|||:|:.|:||||||::||||
  Fly   586 DLFPLLECLSSIATALQSGFLPYCDPVYRRCISLIEQTINQEMLCKQNQTYDHPDKERMIVALDL 650

  Fly   609 VSGLIEGLQSLIEPLVANSKLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYPYTAHFILI 673
            :|||.|||...||.|||||.::.||.|||.||:||||||||||||||:.|||..|:|:.|.|..|
  Fly   651 LSGLAEGLDRHIETLVANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHPFMADFFPI 715

  Fly   674 LVQNLNPSVVGVCNNAVWAIGQICVKLGEETKPYVRLLLSELMILMNRQDIPKNLSRNAAITLGR 738
            |.|||||..:.|||||.||||:||:|||||||.|:||:||:|.|::||.:.||.|..|.|||:||
  Fly   716 LGQNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIINRPNTPKTLLENTAITIGR 780

  Fly   739 LGNACPDEVAPYLPEFLRQWCLLLRYAYDHDEKYLSFMGMCHMIRENPGGVVPDFLFFCDAIASW 803
            ||..||.|||||||||:||||..||:..|:|||..:|.||||||..||.|||.||:|||||||||
  Fly   781 LGYVCPVEVAPYLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVADFIFFCDAIASW 845

  Fly   804 DNPPQDLRQMIRRIIEGFKNQTGAENWLIFLGKFPQPLACRLIELYDI 851
            .|||:||.|||::|:.|||.|.|.|||..|:.:||..||.||..:|:|
  Fly   846 VNPPEDLHQMIQKILHGFKTQVGEENWRRFVEQFPPTLAERLTTMYNI 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8219	NP_648038.1	KAP95	28..728	CDD:227540	518/741 (70%)
		HEAT repeat	104..132	CDD:293787	27/27 (100%)
		HEAT repeat	145..175	CDD:293787	28/29 (97%)
		HEAT repeat	186..212	CDD:293787	14/25 (56%)
		HEAT repeat	225..254	CDD:293787	21/28 (75%)
		HEAT repeat	360..388	CDD:293787	24/27 (89%)
		HEAT repeat	400..430	CDD:293787	23/29 (79%)
		HEAT repeat	442..468	CDD:293787	23/25 (92%)
		HEAT repeat	629..657	CDD:293787	21/27 (78%)
		HEAT repeat	667..699	CDD:293787	20/31 (65%)
		HEAT repeat	710..738	CDD:293787	14/27 (52%)
Tnpo	NP_477368.1	KAP95	22..754	CDD:227540	514/731 (70%)
		HEAT repeat	127..155	CDD:293787	27/27 (100%)
		HEAT repeat	172..202	CDD:293787	28/29 (97%)
		HEAT repeat	213..239	CDD:293787	14/25 (56%)
		HEAT repeat	252..281	CDD:293787	21/28 (75%)
		HEAT repeat	402..430	CDD:293787	24/27 (89%)
		HEAT repeat	442..472	CDD:293787	23/29 (79%)
		HEAT repeat	481..510	CDD:293787	25/28 (89%)