Protein Alignment CG8219 and tnpo1

DIOPT Version :10

• Sequence 1: NP_648038.1
• Gene: CG8219 / 38722
• FlyBaseID: FBgn0035693
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_004910877.1
• Gene: tnpo1 / 100492001
• XenbaseID: XB-GENE-493792
• Length: 918
• Species: Xenopus tropicalis
• Alignment Length: 916
• Identity: 517/916 - (56%)
• Similarity: 656/916 - (71%)
• Gaps: 69/916 - (7%)

  Fly     3 WTPRDEGLQQLLPILKDSQSPGKATQLAVQE-----------------------TENEATRSMSG 44
            |.|.::||||:|.:||:||||...||.|||:                       :|:|.|||:||
 Frog     5 WKPDEQGLQQILQLLKESQSPDNNTQRAVQQKLEQLNQFPDFNNYLIFVLTKLKSEDEPTRSLSG 69

  Fly    45 LILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILITTIASNIGLHNWPQLLPSLC 109
            ||||||::.|.........::||.:||..:||:||.||.|||||||||||...|.|||:|||.||
 Frog    70 LILKNNVKAHFQNFPNGVTDFIKSECLNNIGDASPLIRATVGILITTIASKGELQNWPELLPKLC 134

  Fly   110 EMLDNQDYNVCEGAFSALQKICEDSAGILEN----MPLNTMIPKFLEYFKHSSPKIRSHAIACIN 170
            .:||::|||.|||||.||||||||||.||::    .|||.||||||::||||||||||||:||:|
 Frog   135 GLLDSEDYNTCEGAFGALQKICEDSAEILDSDILERPLNVMIPKFLQFFKHSSPKIRSHAVACVN 199

  Fly   171 QFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHALVGLVGVRIDLMMPHMSQIIELILLR 235
            ||||.|:|||||:|||.|:||..:.:|.:|.||.|||.|||.|:.||:|.::|||..|:|.:|||
 Frog   200 QFIIGRTQALMLHIDSFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLLR 264

  Fly   236 SQDADENVALQATEFWLSLGKQRNCRDILSPILSQLVPVLVSRTQYTETDIILLKGDVGEDDKEP 300
            :||.||||||:|.||||:|.:|..|:|:|...|::|:||||:..:|:|.|||||||||.||:..|
 Frog   265 TQDQDENVALEACEFWLTLAEQPICKDVLCRHLAKLIPVLVNGMKYSEIDIILLKGDVEEDEAIP 329

  Fly   301 DRQQDISPRFHMSRV-------HGISNELDENSDDDMWD----SALNLRKCSACALDIISKIFGD 354
            |.:|||.||||.||.       .||  |.|::.||::.|    |..|:|||||.|||:::.:|.:
 Frog   330 DSEQDIRPRFHRSRTVAQPHEEDGI--EEDDDDDDELDDDENISDWNIRKCSAAALDVLANVFRE 392

  Fly   355 VCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITCLSDKKPLVRSI 419
            ..||.:||:|||.|||.|||:||||::.|||||||||||:||:||||||:||.||||||.|||||
 Frog   393 ELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSI 457

  Fly   420 TCWTFMRFPKWVLNQPHDKYLEPLIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVPYLENM 484
            ||||..|:..||::||.|.||:||:.||||.||||||||||||||||..|||||||:|||||..:
 Frog   458 TCWTLSRYAHWVVSQPPDMYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYI 522

  Fly   485 LKTFVLAFSKYHQRNLLIMYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDIIYLL 549
            |.|.|.|||||..:||||:||.:|.||:|||||||||:||.:|||||:.|||::||:|||:..||
 Frog   523 LDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNVLKDEDKDLFPLL 587

  Fly   550 ECLSSIATALQSSFLPYCDSVYRKGISIIEETINQDM---------------------MCKQSQS 593
            |||||:||||||.|||||:.||::.::::::|:.|.|                     :|..||:
 Frog   588 ECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLQQSMTDQLQSDRCTVSPVENNPRPDVCPDSQA 652

  Fly   594 T--------DYPDKERMVIALDLVSGLIEGLQSLIEPLVANSKLLQLLCQCMGDVMPEVRQSSFA 650
            .        :.|||:.|::||||:|||.|||...||.|||.|.:|.|:.|||.|.||||||||||
 Frog   653 LHNAQPDQYESPDKDFMIVALDLLSGLAEGLGGHIEQLVARSNILTLMYQCMQDKMPEVRQSSFA 717

  Fly   651 LLGDLSGACFSQVYPYTAHFILILVQNLNPSVVGVCNNAVWAIGQICVKLGEETKPYVRLLLSEL 715
            |||||:.|||..|....|.|:.||..||||.::.|||||.||||:|.:::|.|.:||:.::|.:|
 Frog   718 LLGDLTKACFQHVKSCIADFMPILGTNLNPELISVCNNATWAIGEISIQMGIEMQPYIPMVLHQL 782

  Fly   716 MILMNRQDIPKNLSRNAAITLGRLGNACPDEVAPYLPEFLRQWCLLLRYAYDHDEKYLSFMGMCH 780
            :.::||.:.||.|..|.|||:||||..||.||||.|.:|:|.||..||...|::||..:|.|:|.
 Frog   783 VEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICT 847

  Fly   781 MIRENPGGVVPDFLFFCDAIASWDNPPQDLRQMIRRIIEGFKNQTGAENWLIFLGKFPQPLACRL 845
            ||..||||||.||:|||||:|||.||.:|||.|..:|:.|||||.|.|||..|..:||.||..||
 Frog   848 MISVNPGGVVQDFIFFCDAVASWINPKEDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERL 912

  Fly   846 IELYDI 851
            ...|.:
 Frog   913 AAYYGV 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8219	NP_648038.1	KAP95	28..728	CDD:227540	433/766 (57%)
		HEAT repeat	104..132	CDD:293787	20/27 (74%)
		HEAT repeat	145..175	CDD:293787	24/29 (83%)
		HEAT repeat	186..212	CDD:293787	13/25 (52%)
		HEAT repeat	225..254	CDD:293787	19/28 (68%)
		HEAT repeat	360..388	CDD:293787	19/27 (70%)
		HEAT repeat	400..430	CDD:293787	22/29 (76%)
		HEAT repeat	442..468	CDD:293787	22/25 (88%)
		HEAT repeat	629..657	CDD:293787	21/27 (78%)
		HEAT repeat	667..699	CDD:293787	18/31 (58%)
		HEAT repeat	710..738	CDD:293787	11/27 (41%)
tnpo1	XP_004910877.1	KAP95	24..787	CDD:227540	432/764 (57%)
		HEAT repeat	95..116	CDD:293787	14/20 (70%)
		HEAT repeat	129..157	CDD:293787	20/27 (74%)
		HEAT repeat	174..204	CDD:293787	24/29 (83%)
		HEAT repeat	215..241	CDD:293787	13/25 (52%)
		HEAT repeat	254..283	CDD:293787	19/28 (68%)
		HEAT repeat	398..426	CDD:293787	19/27 (70%)
		HEAT repeat	438..471	CDD:293787	24/32 (75%)
		HEAT repeat	480..506	CDD:293787	22/25 (88%)
		HEAT repeat	562..593	CDD:293787	20/30 (67%)