Protein Alignment CG8219 and tnpo2b

DIOPT Version :10

• Sequence 1: NP_648038.1
• Gene: CG8219 / 38722
• FlyBaseID: FBgn0035693
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_021333077.1
• Gene: tnpo2b / 100005536
• ZFINID: ZDB-GENE-211110-1
• Length: 889
• Species: Danio rerio
• Alignment Length: 892
• Identity: 512/892 - (57%)
• Similarity: 642/892 - (71%)
• Gaps: 44/892 - (4%)

  Fly     1 MAWTPRDEGLQQLLPILKDSQSPGKATQLAVQE-----------------------TENEATRSM 42
            |.|.|.::||||:|.:|||||||..|||.||||                       :|:|.|||:
Zfish     1 MEWQPDEQGLQQVLQLLKDSQSPDTATQRAVQEKLEQLNQFPDFNNYLIFVLTSLKSEDEPTRSL 65

  Fly    43 SGLILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILITTIASNIGLHNWPQLLPS 107
            ||||||||::.|.....|...::||.:||..:||.||.||.|:|||||||||...|..||:|||.
Zfish    66 SGLILKNNVKAHYQNFPPAVADFIKRECLNNIGDPSPLIRATIGILITTIASKGELQTWPELLPQ 130

  Fly   108 LCEMLDNQDYNVCEGAFSALQKICEDSAGILE----NMPLNTMIPKFLEYFKHSSPKIRSHAIAC 168
            ||.:|:::|||.|||:|.|||||||||:.:|:    |.|||.||||||::|||.|||||||||||
Zfish   131 LCNLLNSEDYNTCEGSFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIAC 195

  Fly   169 INQFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHALVGLVGVRIDLMMPHMSQIIELIL 233
            :|||||.|:||||.|||:.|::|..:.:|.|..||.|||.|||.|:.||||.::|||..||:.:|
Zfish   196 VNQFIIGRAQALMDNIDTFIESLFALATDEDCEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYML 260

  Fly   234 LRSQDADENVALQATEFWLSLGKQRNCRDILSPILSQLVPVLVSRTQYTETDIILLKGDVGEDDK 298
            .|:|||||||||:|.||||:|.:|..|::.||..|.||:|:||:..:|:|.|||||||||.|||.
Zfish   261 QRTQDADENVALEACEFWLTLAEQPICKEALSGHLVQLIPILVNGMKYSEIDIILLKGDVEEDDT 325

  Fly   299 EPDRQQDISPRFHMSRVHGISNE---------LDENSDDDMWDSAL---NLRKCSACALDIISKI 351
            .||.:|||.||||.||...:.:|         :||:.|||  |..|   |||||||.|||:::.:
Zfish   326 IPDSEQDIKPRFHKSRTVTLQHEGGEGEEGEDIDEDEDDD--DDTLSDWNLRKCSAAALDVLANV 388

  Fly   352 FGDVCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITCLSDKKPLV 416
            |.|..||.:||:||..|||.:|||||||::.|||||||||||::|:||||||:||.||.|||.||
Zfish   389 FRDELLPHLLPLLKGLLFHPDWVIKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLCDKKALV 453

  Fly   417 RSITCWTFMRFPKWVLNQPHDKYLEPLIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVPYL 481
            |||.|||..|:..||::||.|.:|:||:.||||.|||.||||||||||||..|||||||:|||||
Zfish   454 RSIACWTLSRYAHWVVSQPPDAHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYL 518

  Fly   482 ENMLKTFVLAFSKYHQRNLLIMYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDII 546
            ..:|.|.|.||.||..:||||:||.:|.||:|||||||:|:||..|||||:.|||.:||:|||:.
Zfish   519 SYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLF 583

  Fly   547 YLLECLSSIATALQSSFLPYCDSVYRKGISIIEETINQDMMCKQSQSTDY--PDKERMVIALDLV 609
            .|||||||:||||||.|||||:.||::.::::::|:.|.||..| |...|  |||:.|::||||:
Zfish   584 PLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYSQ-QPDQYEAPDKDFMIVALDLL 647

  Fly   610 SGLIEGLQSLIEPLVANSKLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYPYTAHFILIL 674
            |||.|||...::.|||.|.::.||.|||.|.|||||||||||||||:.|||..|.|..|.|:.||
Zfish   648 SGLAEGLGGHVDQLVARSNIMTLLFQCMQDTMPEVRQSSFALLGDLTKACFPHVKPCIAEFMPIL 712

  Fly   675 VQNLNPSVVGVCNNAVWAIGQICVKLGEETKPYVRLLLSELMILMNRQDIPKNLSRNAAITLGRL 739
            ..||||..:.|||||.||||:||:::|.|.:|||.|:|..|:.::||.:.||.|..|.|||:|||
Zfish   713 GTNLNPEFISVCNNATWAIGEICMQMGVEMQPYVALVLPHLVEIINRPNTPKTLLENTAITIGRL 777

  Fly   740 GNACPDEVAPYLPEFLRQWCLLLRYAYDHDEKYLSFMGMCHMIRENPGGVVPDFLFFCDAIASWD 804
            |..||.||||.|.:|:|.||..||...|::||..:|.|:|.||..||||||.||:|||||:|||.
Zfish   778 GYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICVMIGVNPGGVVQDFIFFCDAVASWV 842

  Fly   805 NPPQDLRQMIRRIIEGFKNQTGAENWLIFLGKFPQPLACRLIELYDI 851
            ||..|||.|..:|:.|||:|.|.|||..|..:||..|..||...|.:
Zfish   843 NPKDDLRDMFYKILHGFKDQVGEENWQQFSEQFPPILKERLSACYGV 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8219	NP_648038.1	KAP95	28..728	CDD:227540	427/740 (58%)
		HEAT repeat	104..132	CDD:293787	18/27 (67%)
		HEAT repeat	145..175	CDD:293787	24/29 (83%)
		HEAT repeat	186..212	CDD:293787	11/25 (44%)
		HEAT repeat	225..254	CDD:293787	19/28 (68%)
		HEAT repeat	360..388	CDD:293787	18/27 (67%)
		HEAT repeat	400..430	CDD:293787	20/29 (69%)
		HEAT repeat	442..468	CDD:293787	21/25 (84%)
		HEAT repeat	629..657	CDD:293787	21/27 (78%)
		HEAT repeat	667..699	CDD:293787	19/31 (61%)
		HEAT repeat	710..738	CDD:293787	12/27 (44%)
tnpo2b	XP_021333077.1	KAP95	22..758	CDD:227540	427/738 (58%)
		HEAT repeat	93..114	CDD:293787	13/20 (65%)
		HEAT repeat	127..155	CDD:293787	18/27 (67%)
		HEAT repeat	165..202	CDD:293787	28/36 (78%)
		HEAT repeat	213..239	CDD:293787	11/25 (44%)
		HEAT repeat	252..281	CDD:293787	19/28 (68%)
		HEAT repeat	438..466	CDD:293787	19/27 (70%)
		HEAT repeat	479..509	CDD:293787	23/29 (79%)
		HEAT repeat	520..546	CDD:293787	13/25 (52%)
		HEAT repeat	561..592	CDD:293787	20/30 (67%)
		HEAT repeat	661..695	CDD:293787	25/33 (76%)
		HEAT repeat	707..737	CDD:293787	18/29 (62%)
		HEAT repeat	748..776	CDD:293787	12/27 (44%)