Protein Alignment CG7386 and ZNF341

DIOPT Version :10

• Sequence 1: NP_648036.1
• Gene: CG7386 / 38719
• FlyBaseID: FBgn0035691
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001269862.1
• Gene: ZNF341 / 84905
• HGNCID: 15992
• Length: 854
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 129/570 - (22%)
• Similarity: 188/570 - (32%)
• Gaps: 180/570 - (31%)

  Fly   177 QAMGQRRI--ANDKRKLFRLMSCSICQQKFKKQSKFEEHMKHHNDLLPFQCQEESCRKGFTTAGA 239
            :|.|.|.:  |..|.|..:| .||.|.:.|.|....::|::.|....||||  .:|.:.|.....
Human   303 RAKGARGLPEAAGKPKAQKL-KCSYCDKSFTKNFDLQQHIRSHTGEKPFQC--IACGRAFAQKSN 364

  Fly   240 LRLHVDYAH--------------------------SKKED-------------------TVPCTV 259
            ::.|:. .|                          |::||                   :.....
Human   365 VKKHMQ-THKVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQALSTAGEE 428

  Fly   260 EG-------------------CQLVFSRLRLLTIHLKKVHNQARVIAPRGEQSC--KECGVVFRC 303
            ||                   |...||....|..|:.: |...:|      ..|  |.|...|..
Human   429 EGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQ-HKNEQV------YKCVVKSCAQTFPK 486

  Fly   304 PVAMKKHMYTHTGEELPYPCTICGKGF----------YINSALKNHLLRHAGIKNYVCQYCGVRK 358
            .....:|:.:|. |||.|.|.:|||.|          |.:|.|..|..:..... |.|..| |.|
Human   487 LDTFLEHIKSHQ-EELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPKKDNAV-YKCVKC-VNK 548

  Fly   359 TTRQEWSKHILIHTQRNQFKCRICDYATHTKRVLESHVKIVHEKIRNFACQYCGKTFGKAYACKI 423
            .:..|..:|.| .|..:.|.|..|......:|.|..|:. .|.....|.||.|.|.|.:.:..|:
Human   549 YSTPEALEHHL-QTATHNFPCPHCQKVFPCERYLRRHLP-THGSGGRFKCQVCKKFFRREHYLKL 611

  Fly   424 HEMAHTGEKRCECKVCDKKFLHSESLNNHLKIHEKSVERALETYKQVQVNGDASDTQVDSHQLLK 488
            |...|:|||..:|.||:..|...:.|..|:.||        |.:|:
Human   612 HAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH--------EPFKK------------------- 649

  Fly   489 VYAESVASIPKNPRRVEQVDVALLAGTAVNPTDEIQFVQKEGMYLCP-----SCSQGFKSIGNMK 548
                                                       |.||     .||:.|.....:|
Human   650 -------------------------------------------YKCPFSTHTGCSKEFNRPDKLK 671

  Fly   549 RHYKSVHEKVKDFECRFCSRRFANSQSVKQHEWIHTGEKPFECKTCGNRFRQVAALIRHQKVHDE 613
            .|..| |..:|..:|..||:.|:....:.:|:..|||...|.|..|...|.      ||:.:.|.
Human   672 AHILS-HSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFS------RHKYLKDH 729

  Fly   614 K----PAKPLGERNDRKQKVEALRQEIAKVAKKELKDLKNQLALEKQQDT 659
            :    |.|....:..|..:..|..:......:|.|..|.:.|.||:.:||
Human   730 RCRLGPQKDKDLQTRRPPQRRAAPRSCGSGGRKVLTPLPDPLGLEELKDT 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7386	NP_648036.1	zf-AD	10..81	CDD:214871
		C2H2 Zn finger	197..217	CDD:275368	6/19 (32%)
		C2H2 Zn finger	294..314	CDD:275368	5/21 (24%)
		C2H2 Zn finger	323..343	CDD:275368	9/29 (31%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		C2H2 Zn finger	379..400	CDD:275368	5/20 (25%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		C2H2 Zn finger	436..456	CDD:275368	6/19 (32%)
		C2H2 Zn finger	534..555	CDD:275368	8/25 (32%)
		C2H2 Zn finger	563..583	CDD:275368	5/19 (26%)
		zf-H2C2_2	575..600	CDD:463886	8/24 (33%)
		C2H2 Zn finger	591..611	CDD:275368	5/19 (26%)
ZNF341	NP_001269862.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..217
		KREPA	<237..>374	CDD:483960	22/74 (30%)
		COG5048	323..729	CDD:227381	109/497 (22%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..372	CDD:275368	4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	399..434		5/34 (15%)
		C2H2 Zn finger	447..467	CDD:275368	5/20 (25%)
		C2H2 Zn finger	475..497	CDD:275368	5/21 (24%)
		C2H2 Zn finger	505..525	CDD:275368	6/19 (32%)
		C2H2 Zn finger	542..562	CDD:275370	7/21 (33%)
		C2H2 Zn finger	568..588	CDD:275368	5/20 (25%)
		C2H2 Zn finger	596..616	CDD:275368	7/19 (37%)
		C2H2 Zn finger	624..644	CDD:275368	6/19 (32%)
		C2H2 Zn finger	652..677	CDD:275368	8/25 (32%)
		C2H2 Zn finger	685..705	CDD:275368	5/19 (26%)
		C2H2 Zn finger	713..730	CDD:275368	6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	731..763		4/31 (13%)