DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7386 and CG11398

DIOPT Version :9

Sequence 1:	NP_648036.1	Gene:	CG7386 / 38719	FlyBaseID:	FBgn0035691	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	75/284 - (26%)
Similarity:	109/284 - (38%)	Gaps:	59/284 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 EEDVFKLLEKV--DKELEEHSRD-QSEEHFSSAEHNGLEEEKKESEG-------------FNSDD 175
            |.::..||...  |:||..::.: |.||         |.|..:..:|             |.:.:
  Fly     8 EAEILALLPHTYEDEELSLNTEELQFEE---------LNERSQHQQGGSPSFVCRRCPALFLTRE 63

  Fly   176 EQAM---------GQRRIANDKRKLFRLMSCSICQQKFKKQSKFEEHMKHHNDLLPFQCQEESCR 231
            |.|.         ||:..|::.       :|..|.:.|:|.:...:||..|||:..:.|.|  |.
  Fly    64 ELAAHRPTHRYQGGQQTPASEH-------ACDACGRVFQKHNALVDHMNAHNDVRNYPCPE--CP 119

  Fly   232 KGFTTAGALRLHVDYAHSKKEDTVPCTVEGCQLVFSRLRLLTIHLKKVHNQARVIAPRGEQSCKE 296
            ..|........|:...| :|.....|...||:..|.:.|....|:|.||...|.:.      |..
  Fly   120 ARFVQRSNRECHLKNVH-RKVYLHSCPEPGCKKRFQQRRECDQHVKTVHQNERNLV------CDT 177

  Fly   297 CGVVFRCPVAMKKHMYTHTGEELPYPCTICGKGFYINSALKNHLLRHAGIKNYVCQYCGVRKTTR 361
            |...|..||..:||:.:| |....|.|.||||.|........||..|:..|.|:|..||.....|
  Fly   178 CSARFSHPVNYRKHLASH-GSAKSYGCPICGKLFGRPENRDVHLFVHSICKAYICSVCGADYMRR 241

  Fly   362 QEWSKHIL--------IHTQRNQF 377
            .:..:|.|        |..|:.||
  Fly   242 NQLIRHGLASGHHNDPIVRQKPQF 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7386	NP_648036.1	zf-AD	10..81	CDD:214871
		C2H2 Zn finger	197..217	CDD:275368	6/19 (32%)
		C2H2 Zn finger	294..314	CDD:275368	7/19 (37%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		C2H2 Zn finger	351..371	CDD:275368	6/27 (22%)
		C2H2 Zn finger	379..400	CDD:275368
		C2H2 Zn finger	408..428	CDD:275368
		C2H2 Zn finger	436..456	CDD:275368
		C2H2 Zn finger	534..555	CDD:275368
		C2H2 Zn finger	563..583	CDD:275368
		zf-H2C2_2	575..600	CDD:290200
		C2H2 Zn finger	591..611	CDD:275368
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	3/19 (16%)
		C2H2 Zn finger	87..107	CDD:275368	6/19 (32%)
		C2H2 Zn finger	115..136	CDD:275368	5/22 (23%)
		C2H2 Zn finger	144..165	CDD:275368	6/20 (30%)
		C2H2 Zn finger	175..195	CDD:275368	7/19 (37%)
		C2H2 Zn finger	203..223	CDD:275368	8/19 (42%)
		C2H2 Zn finger	231..247	CDD:275368	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930