DRSC/TRiP Functional Genomics Resources

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Protein Alignment D19A and CG10959

DIOPT Version :10

Sequence 1:NP_477304.1 Gene:D19A / 38718 FlyBaseID:FBgn0022935 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_572451.1 Gene:CG10959 / 31743 FlyBaseID:FBgn0030010 Length:443 Species:Drosophila melanogaster


Alignment Length:460 Identity:112/460 - (24%)
Similarity:175/460 - (38%) Gaps:121/460 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   110 AEEEDH---VNYDPLL--NHKMELIENEEDVFKMLEHVDKEAEEVEKEAKVEEDDGGNVSV---- 165
            |.||..   |:.:||.  :.|.|.:.||:        |..|.|:.|:|..:|:|:|..:.:    
  Fly    80 AREEQEFQGVSAEPLAVDSFKKEYLPNED--------VLSEEEDAEQELGLEQDEGNPLRIMVLG 136

  Fly   166 -KMFDDDSSIESGNDNDHDLDFEPNSSDDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRP 229
             |...|:.:|::....|||     :||            .:...|...:....::.|:       
  Fly   137 GKQSVDEETIDTMWQPDHD-----SSS------------ASVNEGCALEALLGVENPQ------- 177

  Fly   230 KKIKPPPPEEEELSDSSSESDDSEDGTSRGDKPKRKRIPIEERHLHRIIDCHICHQK-FKKAIRY 293
                              :....|||              ||            ||. |||..:.
  Fly   178 ------------------DYQPDEDG--------------EE------------HQSVFKKQRQP 198

  Fly   294 EEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFH 358
            :::...|            |.:.:||...|..|:..:| ...:...|:  .|..||...|.|..|
  Fly   199 KDYNCPH------------CDRRYTTQKYLNTHLKMSH-PFPQAFKCV--DCKATFDVDRALAQH 248

  Fly   359 MKKVHGITKAAAPLRDFPCTECDTVFRCPTALKKHMYKHTGEELPYPC--NICGKRFVINSALRD 421
            .:|.|         .:|.|..||.||:...:|.:|:..|:|.. .:.|  ..|||.||....|..
  Fly   249 RRKEH---------TEFACQLCDKVFKSSRSLLRHVQGHSGAR-TFKCEHENCGKSFVNQHNLTS 303

  Fly   422 HLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKR 486
            |...|:..:|:||..||.....|:....|..|||.||.|:|:.|.....:|..|:.| :.:|...
  Fly   304 HRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEH-QAMHSTE 367

  Fly   487 KDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKR------DLP 545
            |.:.|..|...|.:..|...|:..|.|.|..:|||||..:.....|:.|::.|:.:      :..
  Fly   368 KPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMRAHKLQASVNATEGA 432

  Fly   546 PAEPL 550
            .|||:
  Fly   433 EAEPI 437

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
D19ANP_477304.1 zf-AD 12..83 CDD:214871
SFP1 <291..363 CDD:227516 15/71 (21%)
C2H2 Zn finger 343..362 CDD:275368 6/18 (33%)
C2H2 Zn finger 377..397 CDD:275368 7/19 (37%)
zf-H2C2_2 389..414 CDD:463886 8/26 (31%)
C2H2 Zn finger 406..426 CDD:275368 8/21 (38%)
C2H2 Zn finger 434..454 CDD:275368 5/19 (26%)
C2H2 Zn finger 462..483 CDD:275368 5/20 (25%)
C2H2 Zn finger 491..511 CDD:275368 5/19 (26%)
C2H2 Zn finger 519..539 CDD:275368 7/19 (37%)
C2H2 Zn finger 652..673 CDD:275368
C2H2 Zn finger 681..701 CDD:275368
zf-C2H2 707..729 CDD:395048
C2H2 Zn finger 709..729 CDD:275368
CG10959NP_572451.1 C2H2 Zn finger 232..253 CDD:275368 8/22 (36%)
COG5048 <258..416 CDD:227381 52/159 (33%)
C2H2 Zn finger 258..278 CDD:275368 7/19 (37%)
C2H2 Zn finger 289..308 CDD:275368 7/18 (39%)
C2H2 Zn finger 316..336 CDD:275368 5/19 (26%)
C2H2 Zn finger 344..364 CDD:275368 5/20 (25%)
C2H2 Zn finger 372..392 CDD:275368 5/19 (26%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

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