DRSC/TRiP Functional Genomics Resources

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Protein Alignment D19A and CG32772

DIOPT Version :9

Sequence 1:NP_477304.1 Gene:D19A / 38718 FlyBaseID:FBgn0022935 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster


Alignment Length:491 Identity:130/491 - (26%)
Similarity:194/491 - (39%) Gaps:121/491 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   190 SSDDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRPKKIKPPPPEEEELSDSSSES----D 250
            ||.|...:||:.:    ...|||.:..|..:.:.:             :::..|.||||:    |
  Fly    71 SSSDSDAIAQQQQ----HQNPQQQQHQNSQQQQQQ-------------QQQMQSSSSSENLQSQD 118

  Fly   251 DSEDGTSRGDKPKRKRIPIEERHLHRIID--------CHICHQKFKKAIRYEEHMKYHNDLLPFQ 307
            ||||                       :|        |.:|::.|.:......|::.|:....|.
  Fly   119 DSED-----------------------VDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFV 160

  Fly   308 CKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHGITKAAAPL 372
            |..  |.||||.|..||.| :..||. ...:.|:  .|||||.::..|..| :::|      ...
  Fly   161 CTY--CHKGFTQAANLRNH-ERIHTN-DRPYQCV--DCGKTFTQITNLNNH-RRLH------TGE 212

  Fly   373 RDFPCT--ECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCP 435
            |.|.|.  ||...|...|.|..||..|...: .|.||:|.|:|...::|..||..|||:..:.||
  Fly   213 RPFVCNEPECGRSFAQVTNLNNHMKSHHKVQ-QYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCP 276

  Fly   436 YCGVGKTTRQ-EWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFG 499
            .|.......| :.:.|:.||.....::|.:||.....:..|..|:| :|::.| |.|..|..:|.
  Fly   277 RCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLK-MHDEFK-FKCDICPSSFN 339

  Fly   500 KSHACKVHERSHTGEKCCECKI--CGKIFLCEKSLTKHLKT-HEKRDLPPAEPLR-QQLNIPMPG 560
            :....|.|.:.|...:...|.:  |.:.|...:.|:|||.| |...:|||  |.| ::.......
  Fly   340 QESLLKKHVQRHVEGRYLSCPVANCAESFAVRQHLSKHLLTNHAHHELPP--PKRSKKAGTLQTS 402

  Fly   561 QMSVPMPGQMPMQMQTDGLVPMDPNQMPSEDMLKACGGGTAAVPPKPKNSRRVQRVDISQLAGTA 625
            |..:.|.|| |:.:|..                    .|....|||.||.       .:.||.||
  Fly   403 QQPLAMIGQ-PLSLQHT--------------------TGQRGRPPKNKNK-------ATTLAATA 439

  Fly   626 V----------NPIPSVSVPSWSPQVNFTKKEGQHI 651
            :          ..|.:||..|...|:|      ||:
  Fly   440 IKIEINESLHSQHISNVSGLSIQQQIN------QHM 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
D19ANP_477304.1 zf-AD 12..83 CDD:214871
C2H2 Zn finger 343..362 CDD:275368 7/18 (39%)
C2H2 Zn finger 377..397 CDD:275368 8/21 (38%)
zf-H2C2_2 389..414 CDD:290200 9/24 (38%)
C2H2 Zn finger 406..426 CDD:275368 8/19 (42%)
C2H2 Zn finger 434..454 CDD:275368 5/20 (25%)
C2H2 Zn finger 462..483 CDD:275368 6/20 (30%)
C2H2 Zn finger 491..511 CDD:275368 5/19 (26%)
C2H2 Zn finger 519..539 CDD:275368 8/22 (36%)
C2H2 Zn finger 652..673 CDD:275368 130/491 (26%)
C2H2 Zn finger 681..701 CDD:275368
zf-H2C2_2 694..718 CDD:290200
C2H2 Zn finger 709..729 CDD:275368
tolA_full 724..>814 CDD:274303
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 78/269 (29%)
C2H2 Zn finger 133..153 CDD:275368 4/19 (21%)
zf-H2C2_2 145..170 CDD:290200 8/26 (31%)
C2H2 Zn finger 161..181 CDD:275368 10/22 (45%)
zf-H2C2_2 173..198 CDD:290200 11/28 (39%)
C2H2 Zn finger 189..209 CDD:275368 8/22 (36%)
C2H2 Zn finger 217..239 CDD:275368 8/21 (38%)
zf-H2C2_2 231..256 CDD:290200 10/25 (40%)
C2H2 Zn finger 247..267 CDD:275368 8/19 (42%)
C2H2 Zn finger 275..296 CDD:275368 5/20 (25%)
C2H2 Zn finger 304..324 CDD:275368 6/20 (30%)
C2H2 Zn finger 331..351 CDD:275368 5/19 (26%)
C2H2 Zn finger 359..380 CDD:275368 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 121 1.000 Inparanoid score I1302
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.050

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