DRSC/TRiP Functional Genomics Resources

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Protein Alignment D19B and M1BP

DIOPT Version :9

Sequence 1:NP_477297.1 Gene:D19B / 38717 FlyBaseID:FBgn0022699 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_649825.1 Gene:M1BP / 41042 FlyBaseID:FBgn0037621 Length:418 Species:Drosophila melanogaster


Alignment Length:549 Identity:108/549 - (19%)
Similarity:190/549 - (34%) Gaps:183/549 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MNEESQYSIHTVCRTCLSTVDDSAAYDLFRVPG--LAKKLCVCTSLSVEQADGFPKNLCNVCFSK 63
            |::.:...:.:.||.|.....:..:..||....  :...:...|.|.:|.....|..:|..|..:
  Fly     1 MSKSALKHLKSTCRVCAKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSME 65

  Fly    64 LNDLHDFQKQCVDSVQKF------QDLVASNAF--ACQTNFDVLDTSAAVADLPGEEEDNVHFDP 120
            |......:::|:.:.::.      :.....:||  |.....|::.|    ...|.::|....:. 
  Fly    66 LASAVKLRERCIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQT----VKTPDDDEVYATYQ- 125

  Fly   121 LLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPF-----GRVSQDDSFESGNDNDLDADFQI 180
                  ||:         ||..::|:::.::|.:..:     |...:||:.....:.|.|:   |
  Fly   126 ------EIV---------LEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDS---I 172

  Fly   181 SSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPAT 245
            .::|:                        .::|..|.:|..|....|.:|....|..        
  Fly   173 MAEDE------------------------EQQQTLELDEDTELIVGDVNDAYVYDSD-------- 205

  Fly   246 ERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTV---------ESCRKGFTTANGLRVH 301
              |...::| ::...:::           |.:::..:|::         ::.|:|          
  Fly   206 --DEVAVLD-NVLDDEYE-----------HENIVVKKCSLPPKPKVRSDDARRRG---------- 246

  Fly   302 VEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVFRCPTALKKHM 366
                   |..::.|  |.|.......:....|.:| |:.|   :.|.|..|:..|...:.||:||
  Fly   247 -------TGGVYIC--EQCGNHIKGRMAFELHCRR-HRGD---KQFGCELCQSRFCTTSELKRHM 298

  Fly   367 YKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKK 431
            .|||||. ||||:.||:                         |....|||.   ||..|||.|:.
  Fly   299 RKHTGER-PFACKYCGR-------------------------CFTDYTTRV---KHERTHTNERP 334

  Fly   432 YECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGK 496
            |                             .|..|||.|...:..|.|...|:||:...|::|.|
  Fly   335 Y-----------------------------VCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDK 370

  Fly   497 VFLFEKGLTKHLKTH-----EKRDLPKTQ 520
            .|:    |..||.||     .||.|.|.:
  Fly   371 SFM----LPTHLSTHFRSGVHKRHLEKAE 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
D19BNP_477297.1 zf-AD 12..83 CDD:214871 13/78 (17%)
C2H2 Zn finger 255..275 CDD:275368 0/19 (0%)
C2H2 Zn finger 283..335 CDD:275368 8/60 (13%)
C2H2 Zn finger 318..338 CDD:275368 4/19 (21%)
COG5048 <347..512 CDD:227381 49/169 (29%)
C2H2 Zn finger 349..369 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 3/19 (16%)
C2H2 Zn finger 406..426 CDD:275368 6/19 (32%)
C2H2 Zn finger 434..455 CDD:275368 0/20 (0%)
C2H2 Zn finger 463..483 CDD:275368 7/19 (37%)
C2H2 Zn finger 491..511 CDD:275368 7/19 (37%)
C2H2 Zn finger 586..607 CDD:275368
C2H2 Zn finger 615..635 CDD:275368
zf-H2C2_2 627..652 CDD:290200
C2H2 Zn finger 643..663 CDD:275368
M1BPNP_649825.1 zf-AD 13..84 CDD:214871 13/70 (19%)
C2H2 Zn finger 253..273 CDD:275368 5/22 (23%)
COG5048 276..>331 CDD:227381 28/86 (33%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
zf-H2C2_2 293..317 CDD:290200 16/49 (33%)
C2H2 Zn finger 309..329 CDD:275368 9/47 (19%)
zf-H2C2_2 324..346 CDD:290200 12/50 (24%)
C2H2 Zn finger 337..357 CDD:275368 7/19 (37%)
zf-H2C2_2 350..372 CDD:290200 8/21 (38%)
C2H2 Zn finger 365..383 CDD:275368 9/21 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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