Protein Alignment D19B and Zfp358

DIOPT Version :10

• Sequence 1: NP_477297.1
• Gene: D19B / 38717
• FlyBaseID: FBgn0022699
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001101798.1
• Gene: Zfp358 / 360754
• RGDID: 1310416
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 131/568 - (23%)
• Similarity: 192/568 - (33%)
• Gaps: 198/568 - (34%)

  Fly   107 DLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPFGRVSQDDSFESGND 171
            |||.:.||   .||          :.:...::.||.|.|.|::
  Rat   109 DLPSDPED---LDP----------SPKAPDRISESPEPEPEDL---------------------- 138

  Fly   172 NDLDADFQISSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDG----- 231
            |.:..|...|.:|..|.|:.:             |.|...:.:.:|.:.:.||||.|.|.
  Rat   139 NTVSEDGDASLEDPEPEAEEA-------------PPSMLGKPDLDSRDLDPTSSSFDLDPDVIGP 190

  Fly   232 -----NPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCRKG 291
                 :|.|.......|                               |.|.||
  Rat   191 VPLVLDPSDDTLSPAAP-------------------------------HVDSLP----------- 213

  Fly   292 FTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVF 356
                :.|....|...|.::.:.|.           |.             :|.|.|.|.:|.:.|
  Rat   214 ----SSLTATPEILATSSAVVLPA-----------PA-------------SPPRPFSCPDCGRAF 250

  Fly   357 RCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNK 421
            |..:.|.:|...|:||: |:.|..|||.|...:.|..|...|.|.:.:.|..||.....|....|
  Rat   251 RRSSGLSQHRRTHSGEK-PYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACGKAFGWRSTLLK 314

  Fly   422 HILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGE 486
            |..:|:.||.:.|..|..|..:...||.|:: .|...:...|..|.|.||:..|...|.|:||||
  Rat   315 HRSSHSGEKPHHCPVCGKAFGHGSLLAQHLR-THGGPRPHKCPVCAKGFGQGSALLKHLRTHTGE 378

  Fly   487 KCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQGTNALMGDGASGSSTIAKPSPHLRGRVERVD 551
            :...|..|||.|.....|.:|.:||                       |..:|
  Rat   379 RPYPCPQCGKAFGQSSALLQHQRTH-----------------------TAERP------------ 408

  Fly   552 IAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCR 616
                                            :.||.|||.|...||::.|.: :|...:.:.|.
  Rat   409 --------------------------------YRCPHCGKAFGQSSNLQHHLR-IHTGERPYACP 440

  Fly   617 FCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHD 664
            .|.|.|.:...|..|.::|:||:||.|::|||.|.|...|..|.:||:
  Rat   441 HCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHE 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D19B	NP_477297.1	zf-AD	12..83	CDD:214871
		C2H2 Zn finger	255..275	CDD:275368	0/19 (0%)
		SFP1	<266..365	CDD:227516	17/98 (17%)
		C2H2 Zn finger	283..335	CDD:275368	5/51 (10%)
		C2H2 Zn finger	318..338	CDD:275368	1/19 (5%)
		COG5048	<347..512	CDD:227381	56/164 (34%)
		C2H2 Zn finger	349..369	CDD:275368	6/19 (32%)
		C2H2 Zn finger	378..398	CDD:275368	7/19 (37%)
		C2H2 Zn finger	406..426	CDD:275368	6/19 (32%)
		C2H2 Zn finger	434..455	CDD:275368	6/20 (30%)
		C2H2 Zn finger	463..483	CDD:275368	8/19 (42%)
		C2H2 Zn finger	491..511	CDD:275368	7/19 (37%)
		C2H2 Zn finger	586..607	CDD:275368	9/20 (45%)
		C2H2 Zn finger	615..635	CDD:275368	6/19 (32%)
		zf-H2C2_2	627..652	CDD:463886	12/24 (50%)
		C2H2 Zn finger	643..663	CDD:275368	8/19 (42%)
Zfp358	NP_001101798.1	COG5048	<172..446	CDD:227381	92/413 (22%)
		C2H2 Zn finger	243..263	CDD:275368	6/19 (32%)
		C2H2 Zn finger	271..291	CDD:275368	7/19 (37%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..347	CDD:275368	6/20 (30%)
		C2H2 Zn finger	355..375	CDD:275368	8/19 (42%)
		C2H2 Zn finger	383..403	CDD:275368	7/19 (37%)
		C2H2 Zn finger	411..431	CDD:275368	9/20 (45%)
		C2H2 Zn finger	439..459	CDD:275368	6/19 (32%)
		zf-H2C2_2	451..474	CDD:463886	11/22 (50%)
		zf-C2H2	465..487	CDD:395048	9/21 (43%)
		C2H2 Zn finger	467..487	CDD:275368	8/19 (42%)
		PHA03269	551..>638	CDD:165527