DRSC/TRiP Functional Genomics Resources

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Protein Alignment D19B and egl-43

DIOPT Version :9

Sequence 1:NP_477297.1 Gene:D19B / 38717 FlyBaseID:FBgn0022699 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_001022288.1 Gene:egl-43 / 174552 WormBaseID:WBGene00001207 Length:543 Species:Caenorhabditis elegans


Alignment Length:608 Identity:125/608 - (20%)
Similarity:205/608 - (33%) Gaps:176/608 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 EEDNVHFDPL-------LNSKIEIIE----NEEDVFKMLESVEKEVEEVEMEMEQPFGRVSQDDS 165
            :||.:|.:.|       |...|.:|:    |:.:...:|..: ||.::.|               
 Worm    14 KEDELHGNVLIAVTQIALGRTIGVIDKATPNDSNALLILNLI-KEADDGE--------------- 62

  Fly   166 FESGNDNDLDADFQISSDDDIPLAQRSRRGATRGSKA--KGKPKSAAKRQEEESEESEETSSSDD 228
                             |.:|.:.|..|:...:.||.  .|:.....:..|||.:|.::    ||
 Worm    63 -----------------DANICMRQEDRKTFLQTSKIINIGERLLLQRLSEEECDEEDQ----DD 106

  Fly   229 SDG----NPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQ------- 282
            .:.    ..:|:|...:            .|.....:......:||:::.|.:|:|.|       
 Worm   107 LENLILLKDEDRPDSTQ------------SCTKSSSEDSNLNGFEEYIREHGELVPGQTPPDGSH 159

  Fly   283 -CTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRD 346
             |.|  |.|.|::|:||:.| .|.|   .::.|.....|.||:.:...|..| :|||     ...
 Worm   160 KCGV--CPKSFSSASGLKQH-SHIH---CSLKPFRCHLCPKSYTQFSNLCRH-RRVH-----SDG 212

  Fly   347 FPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGV 411
            :.|..|:.......||.||.        | .||:.....|:.:.|       ||:.       |.
 Worm   213 WTCPTCQSQMPSQAALTKHR--------P-VCEMTALYKPLMAQL-------AGLS-------GA 254

  Fly   412 GKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHAC 476
            |......:..|||          :....|.|...|........::..:...|..........|| 
 Worm   255 GGLGSVPYWPHIL----------QMATQAPHFPLAFLAANPEAYKLMQQTTCASPDAECSSGHA- 308

  Fly   477 KIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEK------RDLPKTQGTN-------ALMGD 528
              .|.|.|..:..:.....|     ...|..::|..|      ||.....|.:       .::.:
 Worm   309 --SESSPTTTEPVDLTATPK-----PPSTSEMETTSKSDDGEDRDSIGDSGNDDDDDSEAGVLDE 366

  Fly   529 GASGSSTIAKPSPHLRGRVERVDIAQLAGTVA-------------NPIPSVNLPSWSPQVNFTKK 580
            .::.:||..:|:.|   .:..:..|...|..|             |..|:|..|....:.....|
 Worm   367 SSTTTSTKKRPTSH---TISDILAAPQLGAQALNSTFLGMLQRSLNYNPAVPSPHSFLRAMSGAK 428

  Fly   581 EGQHICPDCGKGFNHVSNMKLHYKVVHQKVKD-FCCRFCPKRFAKKQYLRHHEYIHTGEKPYECK 644
            .........|.|                  || :.|:||.|.|.:...|..|...||||:||:|:
 Worm   429 ASSSPSSSSGSG------------------KDRYTCKFCQKVFPRSANLTRHLRTHTGEQPYKCQ 475

  Fly   645 VCGKHFRQEQVLKTHMK-VHDKP 666
            .|.:.|.....|:.|:: :|:||
 Worm   476 YCERSFSISSNLQRHVRNIHNKP 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
D19BNP_477297.1 zf-AD 12..83 CDD:214871
C2H2 Zn finger 255..275 CDD:275368 3/19 (16%)
C2H2 Zn finger 283..335 CDD:275368 17/51 (33%)
C2H2 Zn finger 318..338 CDD:275368 6/19 (32%)
COG5048 <347..512 CDD:227381 30/164 (18%)
C2H2 Zn finger 349..369 CDD:275368 6/19 (32%)
C2H2 Zn finger 378..398 CDD:275368 4/19 (21%)
C2H2 Zn finger 406..426 CDD:275368 5/19 (26%)
C2H2 Zn finger 434..455 CDD:275368 3/20 (15%)
C2H2 Zn finger 463..483 CDD:275368 4/19 (21%)
C2H2 Zn finger 491..511 CDD:275368 2/19 (11%)
C2H2 Zn finger 586..607 CDD:275368 2/20 (10%)
C2H2 Zn finger 615..635 CDD:275368 7/19 (37%)
zf-H2C2_2 627..652 CDD:290200 11/24 (46%)
C2H2 Zn finger 643..663 CDD:275368 5/20 (25%)
egl-43NP_001022288.1 SFP1 <115..210 CDD:227516 29/118 (25%)
C2H2 Zn finger 161..181 CDD:275368 10/22 (45%)
C2H2 Zn finger 189..209 CDD:275368 6/20 (30%)
C2H2 Zn finger 215..232 CDD:275368 5/16 (31%)
zf-C2H2 444..466 CDD:395048 7/21 (33%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
zf-H2C2_2 458..482 CDD:404364 10/23 (43%)
C2H2 Zn finger 474..495 CDD:275368 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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