DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10274 and ZAP1

DIOPT Version :9

Sequence 1:NP_001097525.1 Gene:CG10274 / 38716 FlyBaseID:FBgn0035690 Length:863 Species:Drosophila melanogaster
Sequence 2:NP_012479.1 Gene:ZAP1 / 853390 SGDID:S000003592 Length:880 Species:Saccharomyces cerevisiae


Alignment Length:362 Identity:94/362 - (25%)
Similarity:148/362 - (40%) Gaps:62/362 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 QRLRDNSR--MIPKAKAAVIKEEDQE----FPTGSEEEDEDGEKSKSRRKRIPPGERHLHRIIDC 271
            :|.|:.|.  .:||     :..::|:    :||...|..:......|....|.|..:....|   
Yeast   509 ERFRNQSEPPSLPK-----VTHQNQKNRRSWPTKDLESTDFSSLEDSLPSSISPPIQTTSTI--- 565

  Fly   272 HICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHI--DHAHTELS---EVHSC 331
                 .|....:.|:    :|||   :||.:.|.:..::...|:.|:  ||...:..   |..:|
Yeast   566 -----NFNWCFKEEK----NNDL---KCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLAC 618

  Fly   332 NVDGCGKTFPRIRLLTFHMKKMHGIT---KAAAPPRDYP---CTECEKVFRCPMALKKHMYKHDG 390
            |.:.|.........:..|:...|||.   :.|.|....|   ..|...:..||......:.|.||
Yeast   619 NWEDCDFLGDDTCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCPNPQTHEVSKADG 683

  Fly   391 -------------------KELPFPCNICGKRFVINSALKDHLMR-H--AGIKNYVCPYCGVGKT 433
                               :::....:.|.|.|.....|.|||.. |  .|...|.|.:....:|
Yeast   684 APDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRT 748

  Fly   434 --TRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACK 496
              .||:...|:..|::.|.:||..|:....::::|..|.: .|...|.|.|..|.|.|..|.:.|
Yeast   749 FPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTR-THSGEKPYKCHICNKKFAISSSLK 812

  Fly   497 IHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKR 533
            ||..||||||..:||:|||:|....:|:||:|||:|:
Yeast   813 IHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKK 849

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10274NP_001097525.1 zf-AD 15..90 CDD:214871
C2H2 Zn finger 334..353 CDD:275368 2/18 (11%)
C2H2 Zn finger 368..388 CDD:275368 3/19 (16%)
COG5048 394..729 CDD:227381 52/145 (36%)
C2H2 Zn finger 397..417 CDD:275368 7/20 (35%)
C2H2 Zn finger 425..445 CDD:275368 5/21 (24%)
C2H2 Zn finger 453..474 CDD:275368 4/20 (20%)
C2H2 Zn finger 482..502 CDD:275368 8/19 (42%)
C2H2 Zn finger 510..530 CDD:275368 10/19 (53%)
C2H2 Zn finger 638..659 CDD:275368
C2H2 Zn finger 667..687 CDD:275368
zf-H2C2_2 680..704 CDD:290200
C2H2 Zn finger 695..715 CDD:275368
ZAP1NP_012479.1 COG5048 292..761 CDD:227381 57/271 (21%)
C2H2 Zn finger 743..762 CDD:275368 4/18 (22%)
SUF4-like 766..>814 CDD:411020 15/48 (31%)
C2H2 Zn finger 770..795 CDD:411020 5/25 (20%)
C2H2 Zn finger 770..790 CDD:275368 4/20 (20%)
C2H2 Zn finger 798..818 CDD:275368 8/19 (42%)
zf-H2C2_2 810..834 CDD:404364 14/23 (61%)
C2H2 Zn finger 826..846 CDD:275368 10/19 (53%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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