DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10274 and CG8319

DIOPT Version :9

Sequence 1:NP_001097525.1 Gene:CG10274 / 38716 FlyBaseID:FBgn0035690 Length:863 Species:Drosophila melanogaster
Sequence 2:NP_649920.2 Gene:CG8319 / 41165 FlyBaseID:FBgn0037722 Length:383 Species:Drosophila melanogaster


Alignment Length:536 Identity:116/536 - (21%)
Similarity:182/536 - (33%) Gaps:191/536 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 VCRICLNRLPENGGGA-----GSFDLFL---IPG--LAKKLCVCTSLAVEQSDGFPKCLCAQCFS 69
            :||||        |||     |.||..:   :.|  ||:.:..|..:.::..|..|:.:|..|..
  Fly     4 LCRIC--------GGASENMLGIFDDQVEEYVDGAKLAEMVKTCADVQLDPDDAMPQKMCISCVH 60

  Fly    70 RLDDMHEFQKLCVDSVQKFQDMVARNVFCPPASAQMKNFDLLN--VAGNEPELVGQDEEDRINFD 132
            .....:.|::.|.::.:||.                  ..:||  |..:||              
  Fly    61 DARTAYGFKRRCEENYKKFY------------------LAILNGQVIKDEP-------------- 93

  Fly   133 PLLDHKMEMIENEEDVFKMLEHVDK---EA-EQVEKEVKQDELDAADLMTIFAAESSEESEEDID 193
                       |||| |..:|:.||   || :::.||:|:....|:                   
  Fly    94 -----------NEED-FLFIENPDKGNLEAKKKLNKEIKKTHQTAS------------------- 127

  Fly   194 QDVDFEPNSSDGDDDVPLAQRLRDNSRMIPKAKAAVIKEEDQEFPTGSEEEDEDGEKSKSRRKRI 258
                                  |.....|..::|                    |.:.:|.:   
  Fly   128 ----------------------RTTKSSITTSRA--------------------GRQLRSIK--- 147

  Fly   259 PPGERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHT 323
                   ::...|.:|.::||:.|...:|||.|::  ...|  :.|.:.|.    .:..:|:   
  Fly   148 -------NQTFKCELCIKQFKRQINLLDHMKVHSN--SHVC--QNCEERFL----FKADLDN--- 194

  Fly   324 ELSEVHSCNVDGCGKTFPRIRLLTFHMKKMHGITKAAAPPRDYPCTECEKVFRCPMALKKHMYKH 388
                 |.|                  .:..:...:         |.||.|||....:|..|..|.
  Fly   195 -----HQC------------------YRNSNSTVE---------CPECLKVFSSTQSLDSHKCKD 227

  Fly   389 DGKELPFPCNICGKRFVINSALKDHLMRHAGIKN----YVCPYCGVGKTTRQEWNTHILTHTQEK 449
            ..:..||.|..|.:.|.....||.||:.||..|.    :.|.||..|...:.....||..|..|:
  Fly   228 MQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKSALKVHIHAHMGER 292

  Fly   450 KFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCG 514
            ...|..|.....:||:|..||:| |...|.|.|.:|.|||..::....|...|:.|:..:|.:|.
  Fly   293 PHACPFCVSNFRSKQALKVHIRI-HTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCSICL 356

  Fly   515 KKFLYPKSLTKHLKTH 530
            :.|    ....|||.|
  Fly   357 QDF----REKHHLKRH 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10274NP_001097525.1 zf-AD 15..90 CDD:214871 22/84 (26%)
C2H2 Zn finger 334..353 CDD:275368 0/18 (0%)
C2H2 Zn finger 368..388 CDD:275368 8/19 (42%)
COG5048 394..729 CDD:227381 46/141 (33%)
C2H2 Zn finger 397..417 CDD:275368 7/19 (37%)
C2H2 Zn finger 425..445 CDD:275368 6/19 (32%)
C2H2 Zn finger 453..474 CDD:275368 8/20 (40%)
C2H2 Zn finger 482..502 CDD:275368 6/19 (32%)
C2H2 Zn finger 510..530 CDD:275368 6/19 (32%)
C2H2 Zn finger 638..659 CDD:275368
C2H2 Zn finger 667..687 CDD:275368
zf-H2C2_2 680..704 CDD:290200
C2H2 Zn finger 695..715 CDD:275368
CG8319NP_649920.2 zf-AD 4..79 CDD:285071 20/82 (24%)
COG5048 <153..368 CDD:227381 69/262 (26%)
C2H2 Zn finger 153..173 CDD:275368 8/19 (42%)
C2H2 Zn finger 179..196 CDD:275368 4/30 (13%)
C2H2 Zn finger 207..227 CDD:275370 8/19 (42%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
C2H2 Zn finger 268..288 CDD:275368 6/19 (32%)
C2H2 Zn finger 296..316 CDD:275368 8/20 (40%)
zf-H2C2_2 308..332 CDD:290200 11/24 (46%)
zf-C2H2 322..344 CDD:278523 7/21 (33%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
C2H2 Zn finger 352..368 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45449796
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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