Protein Alignment CG10274 and D19A

DIOPT Version :10

• Sequence 1: NP_001097525.1
• Gene: CG10274 / 38716
• FlyBaseID: FBgn0035690
• Length: 863
• Species: Drosophila melanogaster
• Sequence 2: NP_477304.1
• Gene: D19A / 38718
• FlyBaseID: FBgn0022935
• Length: 845
• Species: Drosophila melanogaster
• Alignment Length: 898
• Identity: 566/898 - (63%)
• Similarity: 674/898 - (75%)
• Gaps: 95/898 - (10%)

  Fly     6 EAAQYSVHAVCRICLNRLPENGGGAGSFDLFLIPGLAKKLCVCTSLAVEQSDGFPKCLCAQCFSR 70
            |..|||:|::||||||.|..:    .::||:|:|||:||||.||||:|||:|||||.||..|:::
  Fly     3 EGRQYSIHSLCRICLNHLQND----AAYDLYLVPGLSKKLCFCTSLSVEQNDGFPKNLCTLCYTK 63

  Fly    71 LDDMHEFQKLCVDSVQKFQDMVARNVFCPPASAQMKNFDLLNVAGNEPELVGQD----EEDRINF 131
            |:::|:|||.||||||||||:||.|||     |...:||:.     :|.:..||    |||.:|:
  Fly    64 LNELHDFQKQCVDSVQKFQDLVASNVF-----ACQSSFDVF-----DPNVAVQDYPAEEEDHVNY 118

  Fly   132 DPLLDHKMEMIENEEDVFKMLEHVDKEAEQVEKEVKQDELDAADL-MTIFAAESSEESEEDIDQD 195
            ||||:||||:|||||||||||||||||||:||||.|.:|.|..:: :.:|..:||.||..|.|.|
  Fly   119 DPLLNHKMELIENEEDVFKMLEHVDKEAEEVEKEAKVEEDDGGNVSVKMFDDDSSIESGNDNDHD 183

  Fly   196 VDFEPNSSDGDDDVPLAQRLR----------------DNSRMIPKAKAAVIK----EEDQEFPTG 240
            :|||||||  |||:|||||:|                |..:..|:.:...||    ||::...:.
  Fly   184 LDFEPNSS--DDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRPKKIKPPPPEEEELSDSS 246

  Fly   241 SEEED-EDGEK--SKSRRKRIPPGERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVE 302
            ||.:| |||..  .|.:|||||..||||||||||||||||||||||||||||:||||||||||||
  Fly   247 SESDDSEDGTSRGDKPKRKRIPIEERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVE 311

  Fly   303 TCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLTFHMKKMHGITKAAAPPRDYP 367
            ||:||||||.|||:|||||||||||||:|..:||||||||:|||||||||:|||||||||.||:|
  Fly   312 TCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHGITKAAAPLRDFP 376

  Fly   368 CTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGK 432
            ||||:.|||||.|||||||||.|:|||:|||||||||||||||:|||||||||||:|||||||||
  Fly   377 CTECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGK 441

  Fly   433 TTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKI 497
            |||||||.||||||:||||||..|:|||||||:|:||:|:||||.|::||||||||||||||||:
  Fly   442 TTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKV 506

  Fly   498 HEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQR-QVEMGETPGEQFDNPPA 561
            ||.:|||||.||||:|||.||..|||||||||||||.|...|..||: .:.|   ||:.  :.|.
  Fly   507 HERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPAEPLRQQLNIPM---PGQM--SVPM 566

  Fly   562 P-------PVEG-ISIEPIMSRNAADELLKVCAESVATI---PKDPRRVQRVDLAQLAGTAVNPI 615
            |       ..:| :.::|  ::..::::||.|....|.:   ||:.|||||||::||||||||||
  Fly   567 PGQMPMQMQTDGLVPMDP--NQMPSEDMLKACGGGTAAVPPKPKNSRRVQRVDISQLAGTAVNPI 629

  Fly   616 PSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTL 680
            |||||||||||||||||||:|||||||:|||||||||.|||||||||||||||||||||:|||.|
  Fly   630 PSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQIL 694

  Fly   681 RHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISPKFYAAREELEEQERSKREAKR 745
            ||||||||||||||||.||.|||||||||:|.:||| :|
  Fly   695 RHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHE-KP-------------------------- 732

  Fly   746 QADAKRREIAEAAKEQLSSLHKLESSDRSLHSYDEYQEAAAERAAASAELQAQQFEENEVKRLAE 810
                .||.:.|.:.....:..||| .|....::|:||:.|.|||||:|||.|.|.||||.||.||
  Fly   733 ----NRRHVPERSAPTQITFRKLE-PDAEPRNFDQYQDPAVERAAATAELLAHQLEENEAKRKAE 792

  Fly   811 EERRKVQEAAYEQLQLLQHQQEVDKAQSSYDGYYAQKAHADGTTLDALKIDHV 863
            .||:|:..||.|||..||.|||:.||.:||||||||||.::||:|||||||||
  Fly   793 IERQKIAAAACEQLTKLQQQQEIIKATTSYDGYYAQKAQSEGTSLDALKIDHV 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10274	NP_001097525.1	zf-AD	15..90	CDD:214871	45/74 (61%)
		C2H2 Zn finger	334..353	CDD:275368	16/18 (89%)
		C2H2 Zn finger	368..388	CDD:275368	16/19 (84%)
		COG5048	394..729	CDD:227381	243/346 (70%)
		C2H2 Zn finger	397..417	CDD:275368	18/19 (95%)
		C2H2 Zn finger	425..445	CDD:275368	18/19 (95%)
		C2H2 Zn finger	453..474	CDD:275368	13/20 (65%)
		C2H2 Zn finger	482..502	CDD:275368	17/19 (89%)
		C2H2 Zn finger	510..530	CDD:275368	15/19 (79%)
		C2H2 Zn finger	638..659	CDD:275368	18/20 (90%)
		C2H2 Zn finger	667..687	CDD:275368	17/19 (89%)
		C2H2 Zn finger	695..715	CDD:275368	14/19 (74%)
D19A	NP_477304.1	zf-AD	12..83	CDD:214871	45/74 (61%)
		SFP1	<291..363	CDD:227516	62/71 (87%)
		C2H2 Zn finger	343..362	CDD:275368	16/18 (89%)
		C2H2 Zn finger	377..397	CDD:275368	16/19 (84%)
		zf-H2C2_2	389..414	CDD:463886	21/24 (88%)
		C2H2 Zn finger	406..426	CDD:275368	18/19 (95%)
		C2H2 Zn finger	434..454	CDD:275368	18/19 (95%)
		C2H2 Zn finger	462..483	CDD:275368	13/20 (65%)
		C2H2 Zn finger	491..511	CDD:275368	17/19 (89%)
		C2H2 Zn finger	519..539	CDD:275368	15/19 (79%)
		C2H2 Zn finger	652..673	CDD:275368	18/20 (90%)
		C2H2 Zn finger	681..701	CDD:275368	17/19 (89%)
		zf-C2H2	707..729	CDD:395048	16/21 (76%)
		C2H2 Zn finger	709..729	CDD:275368	14/19 (74%)