DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10274 and CG17385

DIOPT Version :9

Sequence 1:	NP_001097525.1	Gene:	CG10274 / 38716	FlyBaseID:	FBgn0035690	Length:	863	Species:	Drosophila melanogaster
Sequence 2:	NP_001286418.1	Gene:	CG17385 / 36603	FlyBaseID:	FBgn0033934	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	72/272 - (26%)
Similarity:	104/272 - (38%)	Gaps:	53/272 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 FQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLTFHMKKMHGITKAAA 361
            |.||  .|.:.|.:.....||....|......:.|.:  |.|:|.....|..|||..:.:
  Fly    16 FSCK--RCDRTFRSKRDQTLHRQEVHNHNKTTYECKL--CAKSFCNSGNLDRHMKVHNDV----- 71

  Fly   362 PPRDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCP 426
              |.:.|..|.|.|...:.|::|...|.| |.||.||.|.|.|...|.:|.|.|.|.|.|.:.|.
  Fly    72 --RPFVCNICSKAFAQAVNLQRHYAVHSG-ERPFTCNFCNKSFTQQSNMKRHKMTHTGEKPFRCQ 133

  Fly   427 YCGVGKTTRQEWNTHILTHTQEKKFKCHICE----HASHNKQSLANHIK---------------- 471
            .||...:.......|.|.|...|.::|:.||    ..|:.|:.|.:|||
  Fly   134 RCGRYFSQLVNLKKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHLQSHIKEGVDVDVPASIQAAAA 198

  Fly   472 IVHEKIKN------YACQYCGKTFG-----KSHACKIHEMTHTGEKRCECKVCGKKFLYP----- 520
            :..|::::      :.|..|...|.     :.|..|.||    ..:|.:.:|.....::|
  Fly   199 LARERLESEQKPSFFECMVCRAIFDTFADYEKHEAKCHE----DHERAQLEVNQMSHMHPDDYLP 259

  Fly   521 -KSLTKHLKTHE 531
             |.....|.|||
  Fly   260 MKFAVPDLDTHE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10274	NP_001097525.1	zf-AD	15..90	CDD:214871
		C2H2 Zn finger	334..353	CDD:275368	7/18 (39%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		COG5048	394..729	CDD:227381	46/175 (26%)
		C2H2 Zn finger	397..417	CDD:275368	9/19 (47%)
		C2H2 Zn finger	425..445	CDD:275368	5/19 (26%)
		C2H2 Zn finger	453..474	CDD:275368	9/40 (23%)
		C2H2 Zn finger	482..502	CDD:275368	7/24 (29%)
		C2H2 Zn finger	510..530	CDD:275368	4/25 (16%)
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	667..687	CDD:275368
		zf-H2C2_2	680..704	CDD:290200
		C2H2 Zn finger	695..715	CDD:275368
CG17385	NP_001286418.1	COG5048	<13..181	CDD:227381	53/176 (30%)
		C2H2 Zn finger	18..39	CDD:275368	6/22 (27%)
		C2H2 Zn finger	48..68	CDD:275368	8/21 (38%)
		C2H2 Zn finger	76..96	CDD:275368	6/19 (32%)
		C2H2 Zn finger	104..124	CDD:275368	9/19 (47%)
		C2H2 Zn finger	132..148	CDD:275368	3/15 (20%)
		C2H2 Zn finger	160..180	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449753
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930