DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10274 and hinf-1

DIOPT Version :9

Sequence 1:	NP_001097525.1	Gene:	CG10274 / 38716	FlyBaseID:	FBgn0035690	Length:	863	Species:	Drosophila melanogaster
Sequence 2:	NP_493579.2	Gene:	hinf-1 / 173348	WormBaseID:	WBGene00009553	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	346	Identity:	80/346 - (23%)
Similarity:	128/346 - (36%)	Gaps:	104/346 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 EEEDEDGEKSKSRRKRIPPGERH------LHRIIDCHI----CHQKFKKAIRYEE---------- 286
            ||..::|....:.:.::....:|      |||.:..|:    |.||..:|:..:|
Worm   168 EEGVQNGNHMNTVQCKVRGCNKHLDSIFQLHRHVSMHVFQADCQQKGSEALIEKEDYIGIESCGF 232

  Fly   287 ----HMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLT 347
                ::.:...||  .|:.|.|...|.:...|..|:.|           ::||.|.. .||:
Worm   233 EPCTNINYEGMLL--NCQWEDCGMPFNSLTELFDHVGH-----------HIDGVGDV-DRIQ--- 280

  Fly   348 FHMKKMHGITKAAAPPRDYPCTEC----------------EKVFRCPMA---------LKKH--- 384
              ....:|..|...|.:...||:.                |||..||..         |..|
Worm   281 --QNFSNGDKKVVFPCKWTACTQVADSKANLRRHARHHSGEKVLACPFCARFFSRRDKLYDHCLR 343

  Fly   385 ---MYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHT 446
               :.|:...|.|:.|.:|.|||....||..|:.||  :.:..||.|.:|...|.|.:.|::|
Worm   344 RTILMKNPEMEDPYLCKLCQKRFGTEKALCMHVTRH--LVSLTCPLCSLGLGCRAELHRHLMT-- 404

  Fly   447 QEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECK 511
                         .|:::|            |::.|..|.|.|........|.:.|: :....||
Worm   405 -------------KHSRRS------------KDFKCDTCSKLFFTESELNRHAVYHS-DVMYSCK 443

  Fly   512 VCGKKFLYPKSLTKHLKTHEK 532
            .|.:||.:.|.|.||:|.|::
Worm   444 HCPEKFKWKKQLMKHMKEHDE 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10274	NP_001097525.1	zf-AD	15..90	CDD:214871
		C2H2 Zn finger	334..353	CDD:275368	5/18 (28%)
		C2H2 Zn finger	368..388	CDD:275368	9/50 (18%)
		COG5048	394..729	CDD:227381	39/139 (28%)
		C2H2 Zn finger	397..417	CDD:275368	8/19 (42%)
		C2H2 Zn finger	425..445	CDD:275368	7/19 (37%)
		C2H2 Zn finger	453..474	CDD:275368	2/20 (10%)
		C2H2 Zn finger	482..502	CDD:275368	5/19 (26%)
		C2H2 Zn finger	510..530	CDD:275368	10/19 (53%)
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	667..687	CDD:275368
		zf-H2C2_2	680..704	CDD:290200
		C2H2 Zn finger	695..715	CDD:275368
hinf-1	NP_493579.2	C2H2 Zn finger	299..316	CDD:275368	2/16 (13%)
		C2H2 Zn finger	324..344	CDD:275368	4/19 (21%)
		C2H2 Zn finger	359..379	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..406	CDD:275368	8/35 (23%)
		C2H2 Zn finger	415..435	CDD:275368	5/19 (26%)
		C2H2 Zn finger	442..462	CDD:275368	10/19 (53%)
		C2H2 Zn finger	473..494	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000