DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10274 and sem-4

DIOPT Version :9

Sequence 1:NP_001097525.1 Gene:CG10274 / 38716 FlyBaseID:FBgn0035690 Length:863 Species:Drosophila melanogaster
Sequence 2:NP_491997.1 Gene:sem-4 / 172435 WormBaseID:WBGene00004773 Length:744 Species:Caenorhabditis elegans


Alignment Length:600 Identity:108/600 - (18%)
Similarity:170/600 - (28%) Gaps:244/600 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   299 CKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLTFH-MKKMHGITKAAAP 362
            |.:::|.:.|::...|..|:..||.:..|:.||:|  |..||...:.:..| .:|.......:.|
 Worm   101 CPIQSCSQSFSSPAALTWHVLDAHEDEQEIFSCDV--CTTTFSNGQDIREHKCQKTLASRSTSVP 163

  Fly   363 PRDYPCTEC-----------------------------------------EKVF---------RC 377
            |...|.:.|                                         .::|         :.
 Worm   164 PSTIPSSVCFLSTPTTPCLQFSINESIGTSEIREEDEEEDMDVEDGEHVANQLFGHLLQKSDDKS 228

  Fly   378 PMA-LKKHMY-----------------------------KHDGKE-------------------- 392
            .|| |..|.:                             :||..:                    
 Worm   229 KMASLFNHAFPPFAAFPNMPPPFLMRQPFDPRADVFAAGRHDNDDDWEALMEISTSDEAEKIRAL 293

  Fly   393 ---------LPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQE 448
                     .|..|.:|.:.....|||:.|...|.|.:.:.|..|....||:....||:..|..:
 Worm   294 VGDKAVPTTDPNQCILCRRVLSCKSALQMHYRTHTGERPFKCKICQRAFTTKGNLKTHMGVHRSK 358

  Fly   449 KKFK------------CHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMT 501
            ..|:            .|..:|.....|.:  ||   |..          .|...|.|..:.:: 
 Worm   359 HSFRGLPISLPPQLAAMHQHQHQIAPPQRI--HI---HNP----------PTSAASAAAAVAQI- 407

  Fly   502 HTGEKRCECKVCGKKFLYPKSLTKHLKTHEK------RVLRAIETYR------------------ 542
               :...:|.:|.::||....|..|:..|..      ||:....|.|                  
 Worm   408 ---QASQQCPICQQRFLNAGELAVHITEHRNSLTQPPRVMPTPTTTRVQTFPFVPFFTTPPSLNA 469

  Fly   543 ---QRQVEMGETPGEQFDNPPAPPVEGISIEPIMSR------------NAAD------------- 579
               ..|..:......|..|..:|..:..|:|..::|            |::|             
 Worm   470 TDMSTQFNLANILSAQLKNDSSPNTDTSSVEEKITRDDPPKMASLSPSNSSDSSSSVRQDILESS 534

  Fly   580 ---ELLK------VCAESVATIPKDPRRVQRVDLAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGK 635
               |.||      :..:.|:|.| :|:....:...|.......|.|...:|..|          |
 Worm   535 EFEEKLKKLEEPPILEQQVSTTP-NPKNENPLLAMQKMWAETEPPPPRQMPVLS----------K 588

  Fly   636 HICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGT 700
            |                             .|..|.|.|:.:..|:.|...|||:|||:|..||.
 Worm   589 H-----------------------------QCGVCFKHFSSSSALQIHMRTHTGDKPFKCDMCGR 624

  Fly   701 HFRQETALKRHQRTH 715
            .|.....||.|..||
 Worm   625 AFTTRGNLKVHMGTH 639

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10274NP_001097525.1 zf-AD 15..90 CDD:214871
C2H2 Zn finger 334..353 CDD:275368 4/19 (21%)
C2H2 Zn finger 368..388 CDD:275368 6/99 (6%)
COG5048 394..729 CDD:227381 80/394 (20%)
C2H2 Zn finger 397..417 CDD:275368 6/19 (32%)
C2H2 Zn finger 425..445 CDD:275368 6/19 (32%)
C2H2 Zn finger 453..474 CDD:275368 5/20 (25%)
C2H2 Zn finger 482..502 CDD:275368 3/19 (16%)
C2H2 Zn finger 510..530 CDD:275368 6/19 (32%)
C2H2 Zn finger 638..659 CDD:275368 0/20 (0%)
C2H2 Zn finger 667..687 CDD:275368 6/19 (32%)
zf-H2C2_2 680..704 CDD:290200 12/23 (52%)
C2H2 Zn finger 695..715 CDD:275368 7/19 (37%)
sem-4NP_491997.1 C2H2 Zn finger 307..327 CDD:275368 6/19 (32%)
zf-H2C2_2 319..344 CDD:290200 7/24 (29%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
lambda-1 553..>610 CDD:212564 17/96 (18%)
zf-C2H2 589..611 CDD:278523 7/50 (14%)
C2H2 Zn finger 591..611 CDD:275368 6/19 (32%)
zf-H2C2_2 603..628 CDD:290200 12/24 (50%)
C2H2 Zn finger 619..639 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I3296
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

Return to query results.
Submit another query.