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Protein Alignment CG10274 and ZNF555

DIOPT Version :10

Sequence 1:	NP_001097525.1	Gene:	CG10274 / 38716	FlyBaseID:	FBgn0035690	Length:	863	Species:	Drosophila melanogaster
Sequence 2:	XP_011526018.1	Gene:	ZNF555 / 148254	HGNCID:	28382	Length:	630	Species:	Homo sapiens

Alignment Length:	630	Identity:	172/630 - (27%)
Similarity:	258/630 - (40%)	Gaps:	139/630 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 IDQDVDFEPNSSDGDDD-----VPLAQRLRDNSRMIPKAKAAVIKE-------EDQEFPTG---- 240
            :|.:..|:.:.|....|     :|...::...:|.:  :.|:|:.:       |||....|
Human    45 VDDETQFKASGSVSQQDIYGEKIPKESKIATFTRNV--SWASVLGKIWDSLSIEDQTTNQGRNLS 107

  Fly   241 --------SEEEDEDGEKSK-----SRRKRIPPGERH----------LHRIIDCHICHQKFKKAI 282
                    .|..|:.||...     :..|:||||.:.          :||       ....|..|
Human   108 RNHGLERLCESNDQCGEALSQIPHLNLYKKIPPGVKQYEYNTYGKVFMHR-------RTSLKSPI 165

  Fly   283 RYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLT 347
            ..  |..|.    |:||  :.|.:.::....||:|:...:.|...|  |.:  |||||||...|.
Human   166 TV--HTGHK----PYQC--QECGQAYSCRSHLRMHVRTHNGERPYV--CKL--CGKTFPRTSSLN 218

  Fly   348 FHMKKMHGITKAAAPPRDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKD 412
            .|: ::|...|.      |.|.:|.|.|....:|..|:..|.| |.|:.|..|||.|..:|..:.
Human   219 RHV-RIHTAEKT------YECKQCGKAFIDFSSLTSHLRSHTG-EKPYKCKECGKAFSYSSTFRR 275

  Fly   413 HLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKI 477
            |.:.|.|.|.|.|..|....:....:..|:::||.||..||..|..|.....:...|: |.|...
Human   276 HTITHTGEKPYKCKECAEAFSYSSTFRRHMISHTGEKPHKCKECGEAFSYSSAFRRHM-ITHTGE 339

  Fly   478 KNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTH--EK-------- 532
            |.|.|:.|||||....:.:.||..|||||..|||.|||.|:||:|..:|.:||  ||
Human   340 KPYECKQCGKTFIYLQSFRRHERIHTGEKPYECKQCGKTFIYPQSFRRHERTHGGEKPYECNQCG 404

  Fly   533 RVLRAIETYR-QRQVEMGETP------GEQFDNPPAPPVEGISIEPIMSRNAADE---------- 580
            :......::| ..:|..||.|      |:.|:.|       ||:...|..:..::
Human   405 KAFSHPSSFRGHMRVHTGEKPYECKQCGKTFNWP-------ISLRKHMRTHTREKPYECKQCGKA 462

  Fly   581 -LLKVC-AESVATIPKDPRRVQRVDLAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHI------ 637
             .|..| .|.|...|:|     :....:|.|.|           :...::..|...:|.
Human   463 FSLSACFREHVRMHPED-----KSYECKLCGKA-----------FYCHISLQKHMRRHTAEKLYK 511

  Fly   638 CPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGTHF 702
            |..||:.|:....:::|.: .|...|.:.|:.|.|.|....:|..|..:||||||::||.||..|
Human   512 CKQCGKAFSWPELLQQHVR-THTVEKPYECKECGKVFKWPSSLPIHMRLHTGEKPYQCKHCGKAF 575

  Fly   703 RQETALKRHQRTHE---------NRPPVISPKFYAAREELEEQER 738
            ...::|:||.|.|.         ..||  :.:|..:..|...|||
Human   576 NCSSSLRRHVRIHTTEKQYKCNVGHPP--ANEFMCSASEKSHQER 618

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.