Protein Alignment CG7376 and lds

DIOPT Version :10

• Sequence 1: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Alignment Length: 1195
• Identity: 219/1195 - (18%)
• Similarity: 358/1195 - (29%)
• Gaps: 545/1195 - (45%)

  Fly   106 SLEFEVAQQEKEHKRPLKT----YVTTKLYDALYEKHRQTVHVEQERSLDL---------PKRFQ 157
            :|:::...:.....:|:.|    ..|.....||..:..:.:||..|   ||         |...:
  Fly   375 TLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLE---DLPGPEVLAEDPVGLK 436

  Fly   158 SQLRKYQQRTVSWMLGREQQITQVPANFIVLHAIDGITRVFKHKYCLQFYPFEEEIPKISLPPGG 222
            ..|..:|:..::||..||::                                        ||.||
  Fly   437 VSLMNHQKHALAWMSWRERK----------------------------------------LPRGG 461

  Fly   223 ILADEMGLGKTVEFLAMLLMNPRPQDSYRNDYWHQRLEEFSDEVPLKRSRISKKDEVFCICTKKH 287
            ||||:||||||:..::.:|       :.:|.   |.:.|..||    .|....:|:       |:
  Fly   462 ILADDMGLGKTLTMISSVL-------ACKNG---QEMSEGKDE----SSDSDSEDD-------KN 505

  Fly   288 GKRVQCTKCRRWQHEMCMTISEKSDLPHLCPSCWSELVKSGERLVESGATIIVSPNAIKMQWFEE 352
            .||...|   .|:                         ..|.:....|.|::|.|.::..||..|
  Fly   506 KKRKSVT---GWK-------------------------SKGRKDTRRGGTLVVCPASLLRQWESE 542

  Fly   353 IHKHIS-PSLKVLLYFGLHSTFWVSPFDLAQYDVVLTDYTILRNEIYHTTDFKSDRQMRHQQRYM 416
            :...:| ..|.|.::.|.:..  .....|..||:|:|.|.|:..|              |:..
  Fly   543 VESKVSRQKLTVCVHHGNNRE--TKGKYLRDYDIVVTTYQIVARE--------------HKSL-- 589

  Fly   417 RPNSPLLMVNWWRVCLDEAQMVESSTSAAAEMVRMLPAINRWAVTGTIDELPPLLEFVGRPEVCR 481
               |.:..|.|.|:.||||.:|.:..|.::..|..|....|||:|||
  Fly   590 ---SAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGT------------------ 633

  Fly   482 PPDAWQTVDKAFQLNYKCEPLLELLEHSLWRTCKSKVEHELGIPPQTEVVHRLELSNVESLYYRE 546
                                                                 .:.|.|...|
  Fly   634 -----------------------------------------------------PIQNKELDVY-- 643

  Fly   547 EHLKCHEQFLAAVAKHTRHNADNSSCLASISPQLLRIILKPFLRIRQTCSVPVVFNSNVSSTDYL 611
                                                .:|| |||    ||
  Fly   644 ------------------------------------ALLK-FLR----CS--------------- 652

  Fly   612 HPQDLLARLKSNNENECKTELRTWASSYNGLAAIYFIKNDFPQAIKYYNLLLKLANEYNEQNISV 676
             |.|               :|.||..         :|.|             |.|...|..|:.:
  Fly   653 -PFD---------------DLHTWKK---------WIDN-------------KSAGGQNRLNLLM 679

  Fly   677 DSVLQIHAIYNLLQASSLAPAEHKLTELEHKKYQAQMSRLEWKYLEDNTRVLESALSSYNENLEK 741
            .|::       |.:..:...::.||..|.:|:.:.....|:.:.:.....|:..:.:.:.:.|.:
  Fly   680 KSLM-------LRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQ 737

  Fly   742 VSELEKRFEGSTLDLLATMVNHKTSLHDAIWNKVRDDFFRQNISVERLENVNSMAGMLYFMDIWH 806
            .:|.|..|            |:::..:...:|:::|.                 .|..|.|   |
  Fly   738 RAERETDF------------NYRSDANKPTYNQIKDP-----------------NGAYYKM---H 770

  Fly   807 NKLQNLKSTLIAEFEFLKGVMQQACEAIKTGVLLSMEIINFIENVTVCHLTDILDANKDKPVKPK 871
            .|...:                                                 |...|.|  |
  Fly   771 EKFARM-------------------------------------------------AGSKKEV--K 784

  Fly   872 KHRYCRLCLIRDSLNQFECL--LFAKKLDEKATVTEGLENPSMEISFIKSIFAFLRSKQDFSEWK 934
            .|....|.|   .|.|..|.  |....||.:.:.|.|..:                |..|..|
  Fly   785 SHDILVLLL---RLRQICCHPGLIDAMLDGEESQTMGDHS----------------SDSDTPE-- 828

  Fly   935 EECQSKLELLSCLQDLVKFQIKYWIEVEYMVKAFDELEMCKMRILLTDDPEEQSNYRILACQLDE 999
                  ::||:                          ::.|:.|..|....:||
  Fly   829 ------IDLLA--------------------------QLNKLAITDTSTDGQQS----------- 850

  Fly  1000 QLQFNQYNLQTSQLNFTRLCGRLKYLKHLKEDSADKPCPICQTQDDVRYVMMVCGHFVCQHCLDS 1064
                                         ..::.|...|:  ..|:.|         :.:...:.
  Fly   851 -----------------------------VANAGDDGPPL--LPDEAR---------IAKASKNL 875

  Fly  1065 MRRKNGRAGVTKCPLCRQDSPQLYYSVRPGAHKSIIGDFSTKISSVVELVLKIKGENEQEKIIVF 1129
            ::|.|        |:.....|                  |:||:.|::::.....::..:|.||.
  Fly   876 LKRSN--------PVFNLHRP------------------SSKINMVIQILKTSILKSSDDKAIVV 914

  Fly  1130 SQWQAILIEIAR---------ALSLNG---IQFRNKCTNKDFDDFKNPLSNVTCLLMPLSKGSKG 1182
            |||.::| :|.|         .|||||   ::.|....| :|:|..|   ....||:.|:.|..|
  Fly   915 SQWTSVL-DILRDHLSKDGVATLSLNGTIPVKNRQDIVN-EFNDRNN---QKRVLLLSLTAGGVG 974

  Fly  1183 LNLIEATHVFLVEPILNPGDERQAIGRIHRFGQKRPTKVHRFIVNETIEENILSL----ITSADD 1243
            ||||.|.|:.|::...||..|.||..||:|.|||:...:::|:..:|:|:.|..|    :..||.
  Fly   975 LNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADG 1039

  Fly  1244 TTT---LSTHWDLENMTLDSLKKLF 1265
            ..|   :|:     .:|:|.||.||
  Fly  1040 VLTGAKVSS-----KLTIDDLKGLF 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828	72/353 (20%)
		PHD_SF	281..320	CDD:473978	5/38 (13%)
		TPR	636..669	CDD:197478	4/32 (13%)
		RING_Ubox	1036..1082	CDD:473075	6/45 (13%)
		SF2_C_SNF	1104..1225	CDD:350180	46/132 (35%)
lds	NP_524850.2	HepA	287..1041	CDD:440319	211/1170 (18%)
		DEXHc_TTF2	439..686	CDD:350830	95/530 (18%)