Protein Alignment CG7376 and CG10445

DIOPT Version :10

• Sequence 1: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Alignment Length: 1334
• Identity: 278/1334 - (20%)
• Similarity: 441/1334 - (33%)
• Gaps: 546/1334 - (40%)

  Fly     7 CEIADE--VP-PES-----------PEDPTEF--RYGKKRWVFKDNLVEHKEEILICIEKCQNAR 55
            |.|.|:  || |:|           |.|..|.  .|.........:..|:.|:.....:..|...
  Fly    17 CSIQDQSSVPVPDSSGEINNWMEPEPVDSLELSGEYADNESAIFVSASEYNEKKAQIDQLVQKIL 81

  Fly    56 TRKLKFRSIRQESGS----CILVLSHEQTHVRAREIEMEVGEQVLPLFFKDFRGSLEFEVAQQEK 116
            |.:.:.|.:.:.:..    |.|.|..|:.:.|...:    ||         |..:|.....|||
  Fly    82 TMEQQQRQLEENASETKELCDLKLHLEKLNARLEAL----GE---------FLDTLRLREDQQE- 132

  Fly   117 EHKRPLKTYVTTKLYDALYEKHRQTVHVEQERSLDLPKRFQSQLRKYQQR---TVSWMLGREQQI 178
                 :|....::|.|          |.||.:..:|    .|.|.:|:|:   |.:       |.
  Fly   133 -----IKIEDNSELVD----------HTEQPKWSNL----YSGLNRYRQKANHTAA-------QF 171

  Fly   179 TQVPANFI----VLH-------AIDG--------ITRVFKHKY-CLQFYPFEEEIPKISLPPGGI 223
            .|..:|.|    .|:       |||.        :.|:.||:. ||::..|.|. .|||   |||
  Fly   172 YQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRER-QKIS---GGI 232

  Fly   224 LADEMGLGKTVEFLAMLLMNPRPQDSYRND-------YWHQ-----------RLEEFSDEVPLKR 270
            |||:||||||:..:|::|.:...::..|.:       .|.|           ::..|.||
  Fly   233 LADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDE----- 292

  Fly   271 SRISKKDEVFCICTKKHGKRVQCTKCRRWQ---------HEMCMTISEKSDLPHLCPSCWSELVK 326
             ..|.|:|......:|....|:..|..:::         .:..:...|:.||....|.  .|:..
  Fly   293 -EESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPE--PEVFS 354

  Fly   327 SGER-------LVESGATIIVSPNAIKMQWFEEIHKHISP-SLKVLLYFGLH-STFWVSPFDLAQ 382
            |.|.       ...|..|::|.|.::..||..|:...::. :::||.:.|.: ....:..|  ..
  Fly   355 SDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAF--RS 417

  Fly   383 YDVVLTDYTILRNEIYHTTDFKSDRQMRHQQRYMRPNSPLLMVNWWRVCLDEAQMVESSTSAAAE 447
            ||:|:|.|.::.||:               :||.. .|||..|.|.||.||||.::.:|.:....
  Fly   418 YDLVITSYNLVVNEL---------------KRYGN-TSPLFAVYWNRVILDEAHIIRNSKTNCCN 466

  Fly   448 MVRMLPAINRWAVTGT------IDELPPLLEFVGRPEVCRPPDAW-QTVDKAF----QLNYKCEP 501
            .|..|.|...||:|||      :|.. .||.||..|.. :....| :.::::.    :||:..:|
  Fly   467 SVCQLRAHCHWALTGTPVQNRGVDVF-ALLRFVNVPNF-QDLQQWKKNLNESMLGHRRLNFIIKP 529

  Fly   502 LLELLEHSLWRTCKSKVEHELGIP--PQTEV-VHRLELSNVESLYYREEHLKCHEQFLAAVAKHT 563
            |:      |.|| |.|::....:|  |..:: :..::||..|...|         |.|:|::|.
  Fly   530 LM------LRRT-KQKLQASGDMPALPSLKIELICVQLSKTEMAVY---------QILSAISKK- 577

  Fly   564 RHNADNSSCLASISPQLLRIILKPFLRIRQTCSVPVVFNSNVSSTDYLHPQDLLARLKSNNENEC 628
                                                           :..|.||.|.|.|::
  Fly   578 -----------------------------------------------IFTQFLLQREKGNSD--- 592

  Fly   629 KTELRTWASSYNGLAAIYFIKNDFPQAIKYYNLLLKLANEYNEQNISVDSVLQIHAIYNLLQASS 693
                                       :.||:|      |...|.|
  Fly   593 ---------------------------LNYYSL------ERTPQFI------------------- 605

  Fly   694 LAPAEHKLTELEHKKYQAQMSRLEWKYLEDNTRVLESALSSYNENLEKVSELEKRFEGSTLDLLA 758
               |.|...|                              .|||..|:
  Fly   606 ---AGHMSDE------------------------------RYNEIYER----------------- 620

  Fly   759 TMVNHKTSLHDAIWNKVRDDFFRQNISVERLENVNSMAGMLYFMDIWHNKLQNLKSTLIAEFEFL 823
                                                                           ||
  Fly   621 ---------------------------------------------------------------FL 622

  Fly   824 KGVMQQACEAIKTGVLLSMEIINFIENVTVCHLTDILDANKDKPVKPKKHRYCRLCLIRDSLNQF 888
            |.:.....|.| .|:                                    |..:.|:|  |.||
  Fly   623 KSLGYNPGEKI-LGI------------------------------------YILVLLLR--LRQF 648

  Fly   889 EC---LLFAKKLDEKATVTEGLENPSMEISFIKSIFAFLRSKQDFSEWKEECQSKLELLSCLQDL 950
            .|   |:..  :...|...|.::|..::.|.:                  |.|.|:::|:.|.
  Fly   649 CCHPGLMIG--MLRGALTAEDVQNVKVDASDV------------------EGQLKMDVLAELD-- 691

  Fly   951 VKFQIKYWIEVEYMVKAFDELEMCKMRILLTDDPEEQSNYRILACQLDEQLQFNQYNLQTSQLNF 1015
                            .|||          ||..::       .|  ||:             :.
  Fly   692 ----------------KFDE----------TDSEDD-------CC--DEE-------------DS 708

  Fly  1016 TRLCGRLKYLKHLKEDSADKPCPICQTQDDVRYVMMVCGHFVCQHCLDSMRRKNGRAGVTKCPLC 1080
            ||..|..| |:.:|::..::..| ..:.||    :.....|..|  |||.|         ...|.
  Fly   709 TRRDGNFK-LEVIKDEIKEENVP-WDSGDD----LPTASSFEDQ--LDSAR---------ALKLL 756

  Fly  1081 RQDSPQLYYSVRPGAHKSIIGDFSTKISSVVELVLKIKGENEQEKIIVFSQWQAILIEIARA--- 1142
            ...:| ::..:||.|...::      |..:.||   :.|.|  :||||.|||.:.|..:.:.
  Fly   757 NPQNP-IFQFIRPSAKLKMV------IDKLEEL---LTGTN--DKIIVTSQWVSYLAIVRKRLQD 809

  Fly  1143 LSLNGIQFRNKCTNKDFD----DFKNPLSNVTCLLMPLSKGSKGLNLIEATHVFLVEPILNPGDE 1203
            ||...:.|..:.|.|:.:    || |..:....||:.|:.|..||||..|.|:.:|:...||..|
  Fly   810 LSWETLDFNGQLTAKEREIVLRDF-NANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLE 873

  Fly  1204 RQAIGRIHRFGQKRPTKVHRFIVNETIEENILSL 1237
            |||..||:|:||.:||.::|::..:|:|:.|.||
  Fly   874 RQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSL 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828	107/422 (25%)
		PHD_SF	281..320	CDD:473978	7/47 (15%)
		TPR	636..669	CDD:197478	3/32 (9%)
		RING_Ubox	1036..1082	CDD:473075	10/45 (22%)
		SF2_C_SNF	1104..1225	CDD:350180	46/127 (36%)
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	258/1238 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	94/362 (26%)