Protein Alignment CG7376 and Iswi

DIOPT Version :10

• Sequence 1: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Alignment Length: 1222
• Identity: 211/1222 - (17%)
• Similarity: 376/1222 - (30%)
• Gaps: 479/1222 - (39%)

  Fly     8 EIADEVPPESPEDPTEFRYGKKRWVFKDNLVEHKEEILICIEKCQNARTRKLKFRSIRQESGSCI 72
            |..:|...|:..|......|:|...| ||.:|..             |:|:..|...:.|
  Fly    10 EATEENSNETTSDAATSSSGEKEAEF-DNKIEAD-------------RSRRFDFLLKQTE----- 55

  Fly    73 LVLSHEQTHVRAREIEMEVGEQVLPLFFKDFRGSLEFEVAQQEKEHKRPLKTYVTTKLYDALYEK 137
             :.:|..|:                            ......|...||.|.....|..|....:
  Fly    56 -IFTHFMTN----------------------------SAKSPTKPKGRPKKIKDKDKEKDVADHR 91

  Fly   138 HRQTVHVEQERSLDL----------------PKRFQS-QLRKYQQRTVSWMLGREQQITQVPANF 185
            ||:|   |||...:|                |...:| ::|.||.|.::||:...:
  Fly    92 HRKT---EQEEDEELLAEDSATKEIFRFDASPAYIKSGEMRDYQIRGLNWMISLYE--------- 144

  Fly   186 IVLHAIDGITRVFKHKYCLQFYPFEEEIPKISLPPGGILADEMGLGKTVEFLAMLLMNPRPQDSY 250
                  :||                          .||||||||||||::.:::|        .|
  Fly   145 ------NGI--------------------------NGILADEMGLGKTLQTISLL--------GY 169

  Fly   251 RNDYWHQRLEEFSDEVPLKRSRISKKDEVFCICTKKHGKRVQCTKCRRWQHEMCMTISEKSDLPH 315
                                              .||.|.
  Fly   170 ----------------------------------LKHFKN------------------------- 175

  Fly   316 LCPSCWSELVKSGERLVESGATIIVSPNAIKMQWFEEIHKHISPSLKVLLYFG---LHSTFWVSP 377
                             ::|..|::.|.:....|..|..|. .|||:.:...|   ..:||....
  Fly   176 -----------------QAGPHIVIVPKSTLQNWVNEFKKW-CPSLRAVCLIGDQDTRNTFIRDV 222

  Fly   378 FDLAQYDVVLTDYTILRNEIYHTTDFKSDRQMRHQQRYMRPNSPLLMVNWWRVCLDEAQMVESST 442
            ....::||.:|.|                      :..:|..|.....||..:.:|||..:::..
  Fly   223 LMPGEWDVCVTSY----------------------EMCIREKSVFKKFNWRYLVIDEAHRIKNEK 265

  Fly   443 SAAAEMVRMLPAINRWAVTGT-----IDELPPLLEFVGRPEVCRPP---DAWQTVDKAFQLNYKC 499
            |..:|::|.....||..:|||     :.||..||.|: .|:|....   |.|...:.....:...
  Fly   266 SKLSEILREFKTANRLLITGTPLQNNLHELWALLNFL-LPDVFNSSEDFDEWFNTNTCLGDDALI 329

  Fly   500 EPLLELLEHSLWRTCKSKVEHELGIPPQTEVVHRLELSNVESLYYREEHLK-------------- 550
            ..|..:|:..|.|..|::||..|  .|:.|:...:.||.::..:|.:..||
  Fly   330 TRLHAVLKPFLLRRLKAEVEKRL--KPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAGKVEKM 392

  Fly   551 CHEQFLAAVAKHTRH---------------------NADNSSCLASISPQL----LRIILKPFLR 590
            ..:..|..:.|.|.|                     |:...:.|..:.|:|    .|:::  |.:
  Fly   393 RLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLI--FSQ 455

  Fly   591 IRQTCSVPVVFNSNVSSTDYLHPQDLLARLKSNNENECKTELRTWASSYNGLAAIYFIKND---- 651
            :.:...:         ..||.|         ..|.|.|:.:.:|.....|.....:.:.|.
  Fly   456 MTRMLDI---------LEDYCH---------WRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFL 502

  Fly   652 FPQAIKYYNLLLKLA---------NEYNEQNISVDSVLQIHAI--------YNLLQASSLAPAEH 699
            |..:.:...|.:.||         :::|.| :.:.::.:.|.|        :.|:..|::   |.
  Fly   503 FMLSTRAGGLGINLATADVVIIYDSDWNPQ-MDLQAMDRAHRIGQKKQVRVFRLITESTV---EE 563

  Fly   700 KLTELEHKKYQAQMSRLEWKYLEDNTRVLESALSSYNENLEKV--------SELEKRFEGSTLDL 756
            |:.|....|.:.....::...|.||    .|...:.:|.|..:        |..|.......:|:
  Fly   564 KIVERAEVKLRLDKMVIQGGRLVDN----RSNQLNKDEMLNIIRFGANQVFSSKETDITDEDIDV 624

  Fly   757 LATMVNHKTSLHDAIWNKVRDDFFRQ----------NISVERLE--------NVNSMAGML---- 799
            :......||:...|..:.:.:...|.          ..||.:.|        .:|::...:
  Fly   625 ILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALGNWIEPPK 689

  Fly   800 ------YFMDIWHNKLQNL------------KSTLIAEFEFLKGVMQQACEAIKTGVLLSMEIIN 846
                  |.:|.:..:...:            |..::.:|:|....:.:         ||..||..
  Fly   690 RERKANYAVDAYFREALRVSEPKAPKAPRPPKQPIVQDFQFFPPRLFE---------LLDQEIYY 745

  Fly   847 FIENV--TVCHLTDI-LDANKDKPVKPKKHRYCRLCLIRDSLNQFECLLFAKKLDEKATVTEGLE 908
            |.:.|  .|...|:: .||.|   |:.::.|                     |:||...:||. |
  Fly   746 FRKTVGYKVPKNTELGSDATK---VQREEQR---------------------KIDEAEPLTEE-E 785

  Fly   909 NPSMEISFIKSIFAFLRSKQDFSEW---------------KEECQSKLELLSCLQDLVKFQIKYW 958
            ....|....:...|:  :|:||:::               .::.:.|..     ::::::...:|
  Fly   786 IQEKENLLSQGFTAW--TKRDFNQFIKANEKYGRDDIDNIAKDVEGKTP-----EEVIEYNAVFW 843

  Fly   959 ------IEVEYMV-----------------KAFDELEMCKMR-----ILLTDDPEEQSNY----- 990
                  .::|.::                 ||.|: :|.:.|     :.|.....:..||
  Fly   844 ERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQ-KMSRYRAPFHQLRLQYGNNKGKNYTEIED 907

  Fly   991 RILACQLDE--------------------QLQFNQYNLQTSQLNFTRLCGRL 1022
            |.|.|.|.:                    |.:|:.:....:.|...|.|..|
  Fly   908 RFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTL 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828	68/363 (19%)
		PHD_SF	281..320	CDD:473978	3/38 (8%)
		TPR	636..669	CDD:197478	6/45 (13%)
		RING_Ubox	1036..1082	CDD:473075
		SF2_C_SNF	1104..1225	CDD:350180
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	199/1172 (17%)