Protein Alignment CG7376 and Etl1

DIOPT Version :10

• Sequence 1: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 897
• Identity: 172/897 - (19%)
• Similarity: 308/897 - (34%)
• Gaps: 282/897 - (31%)

  Fly   523 GIPPQTEVVHRLELSNVESLYYREEHLKCHEQFLAAVAKHTRHNADNSSCLASISPQLLRIILKP 587
            |...||....:|||:..|.          .|:::||               |.|||....:.::.
  Fly    63 GNDSQTPKKTKLELTVKEK----------EERYMAA---------------AKISPHFDTMAIQE 102

  Fly   588 FLRIRQTCSVPVVFNSNVSSTDYLHPQDLLARLKSNNENECKTELRTWASSYNGLAAIYFIKNDF 652
            .|. |....|       .:|..||...   .:.|.:|....|::|:..:   ||::...|..||.
  Fly   103 SLS-RTNWDV-------AASVRYLREN---CKPKGHNGPLAKSKLKPRS---NGISGGNFSDNDH 153

  Fly   653 -------PQAIKYYNLLLKLANEYNEQNISVDSVLQIHAIYNLLQASSLAPAEHKLTELEHKKYQ 710
                   ....:.|:      ::.::..:|.....|...::..:..:|       |.||:..|..
  Fly   154 SDDDDVKQSKDQVYD------SDDSDSEMSTKMTGQRKKVFQFMNEAS-------LIELQSVKTL 205

  Fly   711 AQMSRL---------EWKYLEDNTRVLESALSSYNENLEKVSELEKRFEGSTLDLLATMVNHKTS 766
            ::...|         :|              |...:.||.:     |..|..|:....::|.:.:
  Fly   206 SEKKALAIIDVRPFSDW--------------SDLRQKLESI-----RMSGDLLNYAQELINKQNT 251

  Fly   767 LHDAIWNKVRDDFFRQNISVERLEN-VNSMAGMLYFMDIWHNKLQNLKSTLIAEFEFLKGVMQQA 830
            : .||.:|.       |..|.|||. :::.||::....:..:.|| |....|....:|..:.:|.
  Fly   252 V-AAILSKC-------NNMVSRLEKAISNGAGIVEQPKLLSSGLQ-LADYQIIGLNWLTVMHKQE 307

  Fly   831 CEAI---KTGVLLSMEIINFI----EN--VTVCHLTDILDANKDKPVKPKKHRYCRLCLIRDSLN 886
            ...|   :.|:..::::|.|:    ||  ....||..:..:..|. .:.:..|:|
  Fly   308 MNGILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTLDN-WEAEISRWC---------- 361

  Fly   887 QFECLLFAKKLDEKATVTEGLENPSMEISFIKSIFAFLRSKQDFSEWKEECQSKLELLSCLQDLV 951
                         ...|.|.......|...::..||    |..|:.:.....:...:.|..::..
  Fly   362 -------------PELVVEKYHGSQDERRRMRGRFA----KDGFTGFDVLLTTYHIVGSTPEERK 409

  Fly   952 KFQIKYWIEVEYMVKAFDELEMCK----------------MRILLTDDPEEQSNYRI--LAC--- 995
            .|::   .:::|::  |||..|.|                ||||||..|.:.:...:  |.|
  Fly   410 MFRV---CKLDYVI--FDEAHMLKNMTTQRYANLITINARMRILLTGTPLQNNLLELISLLCFVM 469

  Fly   996 -----------------------QLDEQLQFNQYNLQ-TSQLNFTRLCGRLK--YLKHL-KEDSA 1033
                                   ..||..||.:..:| ..::....:..|||  .||:| |:.|.
  Fly   470 PKFFAKSIEDIKSLFAKKGKSDGDQDEVSQFQETQIQRAKRIMKPFVLRRLKKDVLKNLPKKLSL 534

  Fly  1034 DKPCP----------------------ICQTQDDVRYVMMVCGHFVCQHCL-------------- 1062
            .:..|                      :|.:.:.....:|:....:..|.|
  Fly   535 VEKVPMSSQQKIYYHELVDYYSNNKGEVCSSSERAGIAIMMEMRRIANHPLLMRHYFTDANLRGF 599

  Fly  1063 -------DSMRRKNGR------AGVTKCPLCRQDSPQLYYSVRPGAHKSIIGDFSTKISSVVELV 1114
                   .|.::.|.:      |.::...:.:..:...:|.|:  ...::|.| |.|...:..|:
  Fly   600 SKRLANASSFKKTNEQYIFEELAVMSDFQVYQMMNKHEFYDVK--IPDNLICD-SGKFLYLDTLL 661

  Fly  1115 LKIKGENEQEKIIVFSQWQAILIEIARALSLNGIQF------------RNKCTNKDFDDFKNPLS 1167
            .|:|.|.  .::::|||:..:|..:...|.:....|            ::..|:.:.||
  Fly   662 PKLKAEG--HRVLLFSQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGDD------ 718

  Fly  1168 NVTCLLMPLSKGSKGLNLIEATHVFLVEPILNPGDERQAIGRIHRFGQKRPTKVHRFIVNETIEE 1232
            ::...|:....|..|:||..|....:.:...||.:::||..|.||.||:||..::|.|...||||
  Fly   719 SIFVFLLSTKAGGVGINLTAADTCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEE 783

  Fly  1233 NILSL----------ITSADD-------------TTTLSTHWDLENMTLDSL 1261
            .||..          |||.:.             ||.|....|.|....:||
  Fly   784 GILMAAEEKLKLEKDITSNEKGEVHEQRCVVKLLTTALGLDKDQEEQLNNSL 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828
		PHD_SF	281..320	CDD:473978
		TPR	636..669	CDD:197478	6/39 (15%)
		RING_Ubox	1036..1082	CDD:473075	8/94 (9%)
		SF2_C_SNF	1104..1225	CDD:350180	33/132 (25%)
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	10/66 (15%)
		HepA	<276..795	CDD:440319	106/563 (19%)