Protein Alignment CG7376 and shprh

DIOPT Version :9

• Sequence 1: NP_001261471.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: XP_031758001.1
• Gene: shprh / 101733375
• XenbaseID: XB-GENE-959908
• Length: 1645
• Species: Xenopus tropicalis
• Alignment Length: 1592
• Identity: 416/1592 - (26%)
• Similarity: 658/1592 - (41%)
• Gaps: 483/1592 - (30%)

  Fly    30 RWVFKDNLV------EHKEEILI-------CIEKCQ-----NARTRKLKFRSIRQESGSCILVLS 76
            ||:.|..|:      ....:|.:       |:.|.:     |.|.:|           :|||:
 Frog   183 RWLQKKKLIALYYRSAKSSDIEVGIYLLEACLSKPEFLSQGNGRMKK-----------ACILM-- 234

  Fly    77 HEQTHVRAREIEMEVGEQVLPLFFKDFRGSLEFEVAQQEKEHKRPLKTYVTTKLYDALYEKHRQT 141
                            ::::..|: :|  ::...:...|:|..|.|:.....:|||.:.:.|:|.
 Frog   235 ----------------QRLMETFY-NF--TIPDVIDDNEEESDRELERQNIEELYDYVRQTHQQE 280

  Fly   142 VHVEQERSLDLPKRFQSQLRKYQQRTVSWMLGREQQITQVPANFIVLHAI-DGITRVFKHKYCLQ 205
            .::.|: .:..|... ..||.||...|:|||.:| ...:||:....||.: ..::.:.:.|  :.
 Frog   281 GNLLQQ-DVQHPALI-PVLRPYQNEAVNWMLQKE-NFMEVPSTENTLHPLWREVSTLEEVK--IY 340

  Fly   206 FYPF------EEEIPKISLPPGGILADEMGLGKTVEFLAMLLMNPR------------------- 245
            :.||      |..:|.... ||||||||||||||||.|:::|.:||
 Frog   341 YNPFTGCVIRERPVPGHEW-PGGILADEMGLGKTVEVLSLILCHPRKDVRKDVLTLPEGKLVNYF 404

  Fly   246 ----PQDSYRN------------------------------------------------------ 252
                |..|.||
 Frog   405 IPPPPMKSARNKKEKVADFKSKERIQFPSLRVMILAAIKEISVKKGASIIAIFKYISTIYRYDVQ 469

  Fly   253 ----------------------------------------------------------------- 252
                                                                             
 Frog   470 RNRRLLKRTIEKLISEKIVEQVKGHGLAGSFKLGKNYKENKIQDKSQKLKTKSSKRLQHSLSELR 534

  Fly   253 --------------------DYWHQRLE-----EFSDEVPLKRSRISK-------KDE------- 278
                                ||..|..|     |..|:..:|...:||       |.|
 Frog   535 DHEKEQPEKVKCIHAAAKDHDYCTQHKESTTDTELKDKGEVKERNVSKLNASLETKHENVYADHP 599

  Fly   279 -----------VF----------CICTK----KHGKRVQCTKCRRWQHEMCMTISEKS--DLPHL 316
                       ||          |||.:    .:..||||.:|..|||..|:...:::  ..|..
 Frog   600 HSQEQVCQTGAVFPFNTADYRFECICGELGLYDYKARVQCLQCHLWQHAECVNYKQENLGVTPFY 664

  Fly   317 CPSCWSELVKSGERLVESGATIIVSPNAIKMQWFEEIHKHI-SPSLKVLLYFGLHSTFWVSPFDL 380
            ||.|...:     :.|.:|||:|:||::|..||.:||::|: |.||.|::|.|:....::.|..|
 Frog   665 CPHCLVAM-----KPVPTGATLIISPSSICHQWVDEINRHVQSSSLHVMVYQGVKKHGFLQPQML 724

  Fly   381 AQYDVVLTDYTILRNEIYHT----TDFKSDRQMRHQQRYMRPNSPLLMVNWWRVCLDEAQMVESS 441
            |:.|||:|.|.:||:|:.:.    ::.:..|:.|:|:|||...|||:.|.|||:|||||||||.:
 Frog   725 AEQDVVITTYDVLRSELNYVDIPHSNSEDGRKFRNQKRYMAVPSPLVAVEWWRICLDEAQMVECT 789

  Fly   442 TSAAAEMVRMLPAINRWAVTGT-----IDELPPLLEFVGRPEVCRPPDAWQTVDKAF------QL 495
            |:.||||...|..||||.|:||     :::|..|:.|:|             ||..:      ||
 Frog   790 TAKAAEMALRLSGINRWCVSGTPVQRGLEDLFGLVLFLG-------------VDPYWVKHWWDQL 841

  Fly   496 NYK--CE----PLLELLEHSLWRTCKSKVEHELGIPPQTEVVHRLELSNVESLYYREEHLKCHEQ 554
            .||  |.    ||.:.:...:||:.|..|..::.||||||.||.|..|.||..:|..:|..|.:.
 Frog   842 LYKPYCRKDPFPLYKFISKIMWRSAKKDVLDQIQIPPQTEDVHWLHFSPVERHFYHRQHEVCCQD 906

  Fly   555 FLAAVAKHTRHNADNSSCLASISPQLLRIILKPFLRIRQTCSVPVVFNSNV----SSTDYLHPQD 615
            .||...|.|    |.:..|:|:..:.:..||.|.||:||.|..|.......    .||  :..::
 Frog   907 ALAKFRKIT----DWALKLSSLDRRTVSSILYPLLRLRQACCHPQAVRGEFLPLQKST--MTMEE 965

  Fly   616 LLARLKSNNENECKTELRTWASSYNGLAAIYFIKNDFPQAIKYYNLLLKLANEYNEQNISVDSVL 680
            ||..|:.....||:...|....:.||||.|:.||.::|:|.:.|..:|:.:.|:.|: :..||:.
 Frog   966 LLTSLQKKCRTECEEAHRQLVCALNGLAGIHIIKGEYPEATELYREVLRSSEEHKEK-LKTDSLQ 1029

  Fly   681 QIHAIYNLLQASSLAPAEHK--LTELEHKKYQAQMSRLEWKYLEDNTRVLESALSSYNENLEKVS 743
            ::|:.:||::   |..|:|.  ...|...|...:..:|:..|:..:...:.....:....|:.:.
 Frog  1030 RLHSTHNLME---LLAAKHPGIPPTLRDDKLADETKQLKEHYMSKSNAEVSEGHQALQPVLQSIR 1091

  Fly   744 ELEKRFEGST---LDLLATMVNH--KTSLHDAIWNKVRDDFFRQNISVERLENVNSMAGMLYFMD 803
            ||:::...|:   ||::...|.:  ...|...:.|::...:..|...:...:......|:.|.
 Frog  1092 ELQRKIHFSSPWWLDVIQCAVQYAIDEELVQRVQNELTSIYKHQTNKLSMADKFRDCRGLQYI-- 1154

  Fly   804 IWHNKLQNLKSTLIAEFEFLKGVMQQACEAIKTGVLL----SMEIINFIENVTVCHLTDILDANK 864
                        :..:.|.||...:...:|:|.   |    |.|:   |:..|:|||
 Frog  1155 ------------VTTQMEELKKCQKLVRDAVKN---LEGPPSQEV---IQASTICHL-------- 1193

  Fly   865 DKPVK-PKKHRYCRLCLIRDSLNQFECLLFAKKL------------DEKATVTEGLENPS----- 911
             :|.: |..:  |..|...:...::|..|||..:            ||:..|.:.|...|
 Frog  1194 -RPARLPLNN--CVFCKADELFTEYESKLFAHTVKGQTAIFEEMIEDEEGLVDDRLPTTSRGLWA 1255

  Fly   912 ---MEISFIKSIFAFLRS-KQD-------------FSEWKEECQSKLELLSCLQDLVKFQIKYWI 959
               :|.| :|::.:|.|: :.|             |..||:|              .|...:||:
 Frog  1256 ASELERS-LKAVLSFARTHRMDARVIDEGAIFMELFDSWKKE--------------YKLLHEYWM 1305

  Fly   960 EVEYMVKAFDELEMC--KMRILLTDDPE--------------EQSNYRILACQLDEQLQFNQYNL 1008
            .:...|.|.|||.|.  ::|:.|.|:|:              :|:..::|          |...:
 Frog  1306 VLRDHVSAIDELAMATERLRVRLPDEPKPNPPVLHIIEPHEVDQNRVKLL----------NDKAV 1360

  Fly  1009 QTSQLNFTRLCGRLKYLKHLKEDSAD--------KPCPICQTQDDVRYVMMVCGHFVCQHC---- 1061
            ..|||.  :..|:|.||.:| |.|.|        :|||||......::.::.|||..|..|
 Frog  1361 AKSQLQ--KKLGQLLYLTNL-EKSQDQTTGGVNPEPCPICARHLGKQWAVLTCGHCFCNECVAII 1422

  Fly  1062 LDSMRRKNGRAGVTKCPLCRQDSPQ---LYYSVRPGAHKS----IIGDFSTKISSVVELVLKIKG 1119
            :|.......|:.: ||.:|||.:..   .|.....||::.    :.|..|||:.:||..::||:.
 Frog  1423 VDQYSVGTRRSAI-KCAICRQTTSHKEISYVFTSEGANQEQDIPVKGSHSTKVEAVVRTLIKIQT 1486

  Fly  1120 ENEQEKIIVFSQWQAILIEIARAL--------SLNGI-QFRNKCTNKDFDDFKNPLSNVTCLLMP 1175
            ::...|.:|||.||.:|..||:||        .:||| :|:...:...:|    |..|:  ||:|
 Frog  1487 QDPGAKSLVFSTWQDVLDIIAKALQDNNLVFSQINGIHKFQENLSAFKYD----PKINI--LLLP 1545

  Fly  1176 LSKGSKGLNLIEATHVFLVEPILNPGDERQAIGRIHRFGQKRPTKVHRFIVNETIEENILSLITS 1240
            |..||.|||:||||||.||||||||..|.|||||:||.||.:.|.||||::..||||.:.::|.:
 Frog  1546 LHTGSNGLNIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKSTIVHRFLIKATIEERMQAMIKT 1610

  Fly  1241 AD--DTTTLSTHWDLENMTLDSLKKLFILKEE 1270
            ||  .|:|.....:...:|:..|.:||..:.|
 Frog  1611 ADRSHTSTSMKQSETSALTVADLAELFTEERE 1642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7376	NP_001261471.1	SNF2_N	221..601	CDD:278600	165/609 (27%)
		PHD_SF	281..320	CDD:304600	15/44 (34%)
		TPR	636..669	CDD:197478	11/32 (34%)
		RING	1037..1083	CDD:238093	15/49 (31%)
		HepA	<1096..1238	CDD:223627	68/154 (44%)
		Helicase_C	1108..1214	CDD:278689	53/114 (46%)
shprh	XP_031758001.1	DEAD-like_helicase_N	297..>418	CDD:421690	42/124 (34%)
		DEAD-like_helicase_N	297..>380	CDD:421690	35/86 (41%)
		Linker_histone	432..503	CDD:395429	0/70 (0%)
		PHD_SHPRH	622..668	CDD:277022	15/45 (33%)
		DEXQc_SHPRH	<664..865	CDD:350828	82/218 (38%)
		RING-HC_SHPRH	1391..1441	CDD:319483	14/50 (28%)
		SF2_C_SNF	1470..1595	CDD:350180	62/130 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	255	1.000	Domainoid score	I2016
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6489
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1788
OMA	1	1.010	-	-		QHG49298
OrthoDB	1	1.010	-	-		D110877at33208
OrthoFinder	1	1.000	-	-		FOG0004218
OrthoInspector	1	1.000	-	-		oto104687
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2964
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.980