Protein Alignment fmt and SAP190

DIOPT Version :9

• Sequence 1: NP_001261470.1
• Gene: fmt / 38714
• FlyBaseID: FBgn0035688
• Length: 996
• Species: Drosophila melanogaster
• Sequence 2: NP_012953.2
• Gene: SAP190 / 853899
• SGDID: S000001736
• Length: 1033
• Species: Saccharomyces cerevisiae
• Alignment Length: 1085
• Identity: 190/1085 - (17%)
• Similarity: 358/1085 - (32%)
• Gaps: 365/1085 - (33%)

  Fly     5 KGYAPSANIEALLEKENSTLEEFLDEEDILQECKTQKKNLVNYFTRPEVIRRLVELITTEP--SE 67
            :.|.|:.::          |::.||::::..|.......|:.:...|:|:.:|:|.:|.|.  .|
Yeast    85 ENYRPNLDV----------LDDLLDDDELYTELMCSNFKLLIFLKYPDVLSKLIEYVTNEKILDE 139

  Fly    68 DVPMSKR---------------------------------------------------------- 74
            :...:|:
Yeast   140 ETDSAKKPEIIEGVNDHPILIERDRKDKKEDAEEGGDSEETTNDSDHDSGDERSVDSEETSITLP 204

  Fly    75 --------FRYANMSCEILTLGLPSLDEKLLNDAETLQLLYSYLEKEPPLNPLLSSFFSKTFSML 131
                    .|.|.::.|||:..:..:...::.:.:.|..|:|.|:...||....|::|.|....|
Yeast   205 PESEEQVETRRARIAAEILSADVWPISAAIMQNKDLLGRLWSILDHPAPLPIPASTYFMKINERL 269

  Fly   132 FTKKPEQDWFLYQHMCLQLLEYIKSQKTFLDFICKHFDTPVIPDLIMQMMK----DIEGGRLKRN 192
            .    :.|       ...:||:|.|:.:.:.....|.|.|.:.|.:::::.    |...|.:|
Yeast   270 L----DMD-------ITGMLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSPTGVIK-- 321

  Fly   193 LFEWLTEDKIVERLIAILRNPQETDKHANVADFFCDLINQGRLMRQTEQENDSFEPAFD-GSNPI 256
               .|...:::.:|:..|.........:...||....:        |...|.|.|.|.. |.|.:
Yeast   322 ---ILKSQELIPKLLDHLNPEYGISTQSAAGDFIKAFV--------TLSTNSSNELASGIGPNEL 375

  Fly   257 LKTIEFADTIEALLNVILEPNAQESAILSGISVVLTLIKP------------ITFTDEPNSDRQR 309
            .:.:...:.||.|:.::|:..   :::.:|:.:::.||:.            .|....|.:||..
Yeast   376 TRQLVSEEMIEKLIKIMLKGG---TSLSNGVGIIIELIRKNNSDYDFIQLVYTTLESHPPTDRDP 437

  Fly   310 LLQKREREIHQEVQETVITVMAPRLQEFVHILKNPPAKPTLETTAAVLTPPFGK------TRLQV 368
            :     ..||      ::.:.|..:.:|..:|.        :|...::..|||.      .|.::
Yeast   438 I-----HLIH------LVKLFAKHMPDFADMLD--------KTKLPLMEMPFGNIEPLGFERFKI 483

  Fly   369 CRVFTALLETKHETI----QQAICATEYFSLLLDFFKQYCWNNFLHTEMEKALYVVFYNELSNNN 429
            |.:...||...:.|:    ...:.|.|                   .::|:|..:....|..|..
Yeast   484 CELIAELLHCSNMTLLNEPNGEMIAQE-------------------RDIERAKELETSTEKENIT 529

  Fly   430 TASTEVTDYFTADCL------------INAFLKVGTEESEVE-------MKNALNDAKRAEGGKD 475
            ......:.|:..||:            ||   ..|:||.|:.       ..:..:|||..||.::
Yeast   530 AIVDNKSSYYDKDCVEKDITENLGALQIN---NQGSEEDELNDTGVSSVKLDVKSDAKVVEGLEN 591

  Fly   476 EEGGDIEIEVAAAQEVAAQTPDERQTAAEENQEHEEHMSQVEAAAEA-----TASEDAEPKAQDN 535
            :..| :|:                         ::|.:|..|:..|.     ...:..:...:|.
Yeast   592 DASG-VEL-------------------------YDETLSDTESVRECLREKPLVGDRLKIALEDT 630

  Fly   536 EVKNSEVDGESPTDQQESEATLND------LDKTKTVPSPPPSE-----MQSHLIVNCHLISKLV 589
            ::..|.:|       ..:|...|:      .|..:.:.:.|...     :....:|:.:|..|:|
Yeast   631 KILISILD-------MFTEFPWNNFLHNVIFDIAQQIFNGPLKTGYNRFLLKDYLVDAYLTKKIV 688

  Fly   590 DLWQHNAQAQSAEK--GRRLGYMGHLIKILRHITNCISESEHIGDL----ITSSLSDEDEVKLWQ 648
            |.   :...|..||  |.|.||||||..:...|:..   .|:|.::    ..:::||..|...|:
Yeast   689 DA---DKACQDYEKKTGLRYGYMGHLTLVAEEISKF---KEYIDEMKLTFCNTAVSDRLEEPFWK 747

  Fly   649 SLIDAETGEFSLAVKQQTK-----LLADCNPHEEN---------------------QYNDGSNDY 687
                    |:|..:...|:     :|.|....:|:                     .|.:|.||
Yeast   748 --------EYSETILADTREKYNTVLGDFGNDQESDDDVIRNSDSEDIIGDTEGNENYGNGEND- 803

  Fly   688 TGEI--NAWNVGNLP-YREVDCSELNNTLQDIFFAIDQNRFQFGRNIDDEDDDDDEHGDHSGGGD 749
              |:  |..:.||:. |...:.:|.....:|.....|.:...:..|::..|||.|.....|...:
Yeast   804 --ELLSNGHDSGNMDLYYNFNNNENEENEEDYAEYSDVDNKNYYNNVETNDDDYDSDDGKSKSAE 866

  Fly   750 G--------HGHGMFTKNSNTLNNLADPWDIQFAVLSSAPTQVNTGTANWGTD------------ 794
            .        |..|....|.:...|.:|.|              .:||:.:..|
Yeast   867 SEFTDKISEHRDGNSLYNEDNDENGSDKW--------------TSGTSLFPPDHFPSRSQPSDPK 917

  Fly   795 FNSDNFADFDAHFSTFGSD---------------LGMPISAPPGEEEEEDSSPAPE-------SA 837
            ....|.......|...|.|               .|.|:...|      .:.|.|:       ||
Yeast   918 LQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTP------KTPPRPKTILFNSLSA 976

  Fly   838 TQVNPEEERQPAESIGLAVGKGV---QDNLACTDDQQAEYDNNAN 879
            ...|.|:|.       :|:|..|   .||...:|::.:|.::..|
Yeast   977 LDNNGEDEE-------VALGTSVDDRMDNEISSDEEDSEDEDEEN 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fmt	NP_001261470.1	SAPS	129..465	CDD:282368	65/381 (17%)
SAP190	NP_012953.2	SAPS	266..762	CDD:398279	109/610 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344340
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2073
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1595
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000781
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100938
Panther	1	1.100	-	-	LDO	PTHR12634
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R385
SonicParanoid	1	1.000	-	-		X542
TreeFam	0	0.000	Not matched by this tool.
	9	8.910