Protein Alignment fmt and SAP185

DIOPT Version :10

• Sequence 1: NP_001261470.1
• Gene: fmt / 38714
• FlyBaseID: FBgn0035688
• Length: 996
• Species: Drosophila melanogaster
• Sequence 2: NP_012437.1
• Gene: SAP185 / 853347
• SGDID: S000003634
• Length: 1058
• Species: Saccharomyces cerevisiae
• Alignment Length: 1144
• Identity: 196/1144 - (17%)
• Similarity: 371/1144 - (32%)
• Gaps: 399/1144 - (34%)

  Fly     5 KGYAPSANIEALLEKENSTLEEFLDEEDILQECKTQKKNLVNYFTRPEVIRRLVELI-------- 61
            |.|.|:.          |.|.:.||:|::..|.......|:.|...|||:.:|::.:
Yeast    74 KAYKPNL----------SLLNDLLDDEELYTELMCSNFKLLVYLKYPEVLSKLIDYVRNSTILES 128

  Fly    62 -------------------TTEPSEDVPMSKR--------------------------------- 74
                               |||..|:....|:
Yeast   129 NIDRVTSEDRDLVRGEDKDTTEDFENAKADKKNIDGTFEEKERTRSGEEEELENEENDSASEDTR 193

  Fly    75 ------------FRYANMSCEILTLGLPSLDEKLLNDAETLQLLYSYLEKEPPLNPLLSSFFSKT 127
                        .|.|.::.|||:..:..:...|:.:...|..|:|.|....||:...|::|.|.
Yeast   194 VTLPHELEEHDDTRRARIAAEILSADVWPISSALIENEGLLAKLWSILRLPSPLSIEASTYFMKI 258

  Fly   128 FSMLFTKKPEQDWFLYQHMCLQLLEYIKSQKTFLDFICKHFDTPVIPDLIMQMMK----DIEGGR 188
            ...|.....:           .::|:|..::..:|....|.|.|.:.|.:::::.    :|..|.
Yeast   259 NERLLDMNMD-----------GIIEFILKKEHIVDDFLAHIDNPPLMDFLLKVISTDKPEISNGV 312

  Fly   189 LKRNLFEWLTEDKIVERLIAILRNPQETDKHANVADFFCDLIN-QGRLMRQTEQENDSFEPAFDG 252
            ::  ||:   :..:|.:||.:|....::...:...||...|:. .|....:....        .|
Yeast   313 IQ--LFK---KQNLVPKLIHLLDPVFDSCTQSAAGDFLKALVTISGNCPNEITSS--------IG 364

  Fly   253 SNPILKTIEFADTIEALLNVILEPNAQESAILSGISVVLTLIKP------------ITFTDEPNS 305
            .|.:.:.:...:.::.|::::|:..   :::.:|:.:::.||:.            .|....|.:
Yeast   365 PNELTRQLVSPNMMKQLMDIMLKGG---NSLNNGVGIIIELIRKNNSDYDTIQTNYTTIESHPPT 426

  Fly   306 DRQRLLQKREREIHQEVQETVITVMAPRLQEFVHILKNPPAKPTLETTAAVLTPPFGKTRLQVCR 370
            ||..:           ....::.:.:..:.:|..||..... |.|:|:...: .|.|..|.::|.
Yeast   427 DRDPI-----------YLGYLVKMFSEHMADFNKILTEKKI-PLLQTSYGTI-EPLGFERFKICE 478

  Fly   371 VFTALLETKHETIQQAICATEYFSLLLDFFKQYCWNNFLHTEMEKALYVVFYNELSNNNTASTEV 435
            :...||...:.|:.....|       .|..::      ...|.|:......|.: ||:.:...|.
Yeast   479 LIAELLHCSNMTLLNEPSA-------YDIVRE------RDAERERIFNSQNYVD-SNDRSELKEN 529

  Fly   436 TDYFTADCLINAFLKVGTEESEVEMKNALNDAKRAEGGKDEEGGDIEIEVAAAQEVAAQTPDERQ 500
            .|..|.|.           :.|||     :|..:.|.......|:..|:...:.::       ..
Yeast   530 EDDNTGDA-----------DDEVE-----DDTNQVESANTSIDGEEVIDKLNSLQI-------ET 571

  Fly   501 TAAEENQEHEEHMSQVEAAAEATASEDAEPKAQDNEVKNSEVDGESPTDQQESEATL--NDLDKT 563
            ....:|..:||..|.:             |...:.:.|:.|  .|:|.:.|.|:..|  :|::|.
Yeast   572 NKVNQNMNNEEQHSLM-------------PDFNNGDFKDEE--DENPFEPQYSDVILDSSDIEKN 621

  Fly   564 KTVPSPPPSEMQSHLIVNCHLISKLVDLWQH---------------------------------- 594
            ..| ||...:.....:.:..:|..:::::.|
Yeast   622 FRV-SPNVGDQLKISLQDTRVIDTMLEMFFHFQWNNFLHNVVYDVVQQIFNGPLKIGYNRFLLDD 685

  Fly   595 --------------NAQAQSAEKGR--RLGYMGHLIKILRHITNCISESEHI-----GDLITSSL 638
                          |.:....|||.  ||||||||..|...:|...:..|.:     ...:.|||
Yeast   686 LLINIRLTDMIINGNNECIEYEKGHDTRLGYMGHLTLIAEEVTKFTAYIEEMNITFENTEVMSSL 750

  Fly   639 SD-------EDEVKLWQSLIDAETGEFSLAVKQQTKLLADCNPHEENQYNDGS------NDYTGE 690
            .:       ||.::..:...:|..|:    :.::..:|.|  ..|:..|:.|.      :||..:
Yeast   751 FESKWIAYTEDVLEDLKEKYNAILGD----IAEEGDMLQD--EEEDAVYDKGERTMGTVDDYIND 809

  Fly   691 INAWNVGNLPYREVDCSELNNTLQDIFFAIDQNRFQFGRNIDDEDD-------DDDEHGDHSGGG 748
            |       :....|.|.|                       ::||:       |:||..::.
Yeast   810 I-------MQMDNVRCQE-----------------------EEEDEGEGYVSFDEDEPQEYR--- 841

  Fly   749 DGHGHGMFTKNSNTLNNLADPWDIQFAVLSSAPTQVNTGTANWGTDFNSDNFADFDAHFSTFGSD 813
              :|..:.:|.||:.....|...:.:..::...|:..       .:||.|:.|
Yeast   842 --NGDSVRSKESNSSEGKRDQEQLYYEYVNEDGTKTR-------LNFNPDSDA------------ 885

  Fly   814 LGMPISAPPGEEEEEDSSPAPESATQVNPEEERQPAESIGLAVGKGVQDNLACTDDQQAEYDNNA 878
                ....|||...:...|                     |.:.:...|  ||..:.......||
Yeast   886 ----TEQVPGEVNRDHKIP---------------------LKLKRSFTD--ACKSETIPNNTVNA 923

  Fly   879 NVEKAISDKLAESSVVETAAIVTRLQSVLLDGEDDYEDDEGMWTKPLGADRPSET--EQITPISN 941
            ..|.                 |.:..:.|.||          |     ...||.:  ::.:|..|
Yeast   924 KEES-----------------VFQFSNELSDG----------W-----ESSPSNSIPKRASPSKN 956

  Fly   942 GPDSKV----NELGLP---FSNHANDISSNNVDGHEANI 973
            |.:|.:    .||..|   |..|.::|.|  .:||:.:|
Yeast   957 GMNSPMFQHQFELHSPTDEFGGHKDEILS--AEGHDYDI 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fmt	NP_001261470.1	SAPS	129..459	CDD:398279	56/346 (16%)
SAP185	NP_012437.1	SAPS	259..772	CDD:398279	101/605 (17%)