Protein Alignment Prdm13 and ZNF407

DIOPT Version :10

• Sequence 1: NP_648032.1
• Gene: Prdm13 / 38713
• FlyBaseID: FBgn0035687
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_060227.2
• Gene: ZNF407 / 55628
• HGNCID: 19904
• Length: 2248
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 78/403 - (19%)
• Similarity: 124/403 - (30%)
• Gaps: 162/403 - (40%)

  Fly   104 LSNGELIVSGSLLRQIKLSED--------------------------VYSFNAIFELHGGQVRVR 142
            |.|.|::::.....:..|.||                          :|||        |:....
Human  1303 LGNKEILMNSQHETEFILEEDGPASDSTVESSDVYETIISIDDKGQAMYSF--------GRFDSS 1359

  Fly   143 LVRDVAREDEIVAWFGEELVLLMGIPFL-TPL---------------NIQGNSRYMCHLCHLTFE 191
            ::|....||..:....||.::..|:... .||               :|..::|..|..|....:
Human  1360 IIRIKNPEDGELIDQSEEGLIATGVRISELPLKDCAQGVKKKKSEGSSIGESTRIRCDDCGFLAD 1424

  Fly   192 TPHPLKIHLA------------LGCGRSAMDILWMRLHYALKAAARSHTETQHSPIPATSSTSSA 244
            ....|.:|:|            |.||:|.  .....||..|  |:..|...:.:.:
Human  1425 GLSGLNVHIAMKHPTKEKHFHCLLCGKSF--YTESNLHQHL--ASAGHMRNEQASV--------- 1476

  Fly   245 SPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTTAATPLSYLPSMSMATAPLSTNP---MNAAAQ 306
                   .::|...:.|:.:                          ..|.|..:..   ::...|
Human  1477 -------EELPEGGATFKCV--------------------------KCTEPFDSEQNLFLHIKGQ 1508

  Fly   307 IEAIVSNMG--------------ASKQGHLCIYCGKV--YSRKYGLKIHIRTHTGFKPLKCKFC- 354
            .|.::..:.              ...||::|.||||:  .|.......|||||||.||.|||.|
Human  1509 HEELLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICH 1573

  Fly   355 --LRPFGDPSNLNKHVRLHLQTHPSSSAGVADGGASGADMDGDVDIEGETDADYQCHVCHKSFPR 417
              ....||..|   ||:.||...                             :|:||||..:|..
Human  1574 FATAQLGDARN---HVKRHLGMR-----------------------------EYKCHVCGVAFVM 1606

  Fly   418 RRDLQRHMETRHG 430
            ::.|..|:..:||
Human  1607 KKHLNTHLLGKHG 1619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prdm13	NP_648032.1	KREPA	<250..>352	CDD:483960	24/120 (20%)
		C2H2 Zn finger	323..343	CDD:275368	9/21 (43%)
		C2H2 Zn finger	351..371	CDD:275368	8/22 (36%)
		zf-C2H2	406..427	CDD:395048	8/20 (40%)
		C2H2 Zn finger	408..427	CDD:275368	7/18 (39%)
ZNF407	NP_060227.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..84
		C2H2 Zn finger	188..208	CDD:275368
		C2H2 Zn finger	217..238	CDD:275368
		C2H2 Zn finger	246..268	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..322
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	494..515
		C2H2 Zn finger	590..614	CDD:275371
		C2H2 Zn finger	617..639	CDD:275371
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	667..700
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	821..847
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	910..962
		C2H2 Zn finger	1416..1445	CDD:275371	5/28 (18%)
		C2H2 Zn finger	1446..1468	CDD:275371	8/25 (32%)
		C2H2 Zn finger	1488..1509	CDD:275371	2/46 (4%)
		C2H2 Zn finger	1539..1561	CDD:275368	9/21 (43%)
		zf-H2C2_2	1557..1578	CDD:463886	13/20 (65%)
		C2H2 Zn finger	1569..1589	CDD:275368	8/22 (36%)
		C2H2 Zn finger	1597..1617	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1630..1650	CDD:275368
		zf-H2C2_2	1642..1669	CDD:463886
		C2H2 Zn finger	1658..1680	CDD:275368
		C2H2 Zn finger	1688..1708	CDD:275368
		zf-H2C2_2	1700..1725	CDD:463886
		zf-H2C2_5	1714..1738	CDD:404746
		C2H2 Zn finger	1716..1736	CDD:275368
		zf-H2C2_2	1728..1753	CDD:463886
		C2H2 Zn finger	1744..1761	CDD:275368