DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prdm13 and CG7368

DIOPT Version :9

Sequence 1:	NP_648032.1	Gene:	Prdm13 / 38713	FlyBaseID:	FBgn0035687	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	72/388 - (18%)
Similarity:	116/388 - (29%)	Gaps:	166/388 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EQLLPSTS---ITPTSMTTSSTETTLTATT----------STASPAKRMRMSN--------PRPG 66
            :|:|.:||   :|| ..|.:...:.|.|.|          .:|...|:....|        |..|
  Fly   176 QQVLQNTSWQTLTP-GTTVADYLSHLPANTLPLSLHHFLKYSAETIKKENQQNVVLQVQTGPAIG 239

  Fly    67 V------------YASQYT--PKDTCSMAIPTSALLGSTVMPTDGSRSHCQLSNGELIVSGSLLR 117
            :            .|.|.|  |:...::.:.|.|.:.:|     .:.:....:.|....||...:
  Fly   240 INTLGTTTISIPQQAEQLTLQPQQQATLQVQTQAAVTAT-----ATTATATTAGGSGATSGKKKK 299

  Fly   118 QIKLSEDVYSFNAIFELHGGQVRVRLVRDVAREDEIVAWFGEELVLLMGIPFLTPLNIQGNSRYM 182
            :.|.|:|..:     :|..|::|:....|                              |:..||
  Fly   300 RKKRSKDRKT-----KLRPGEIRLGTALD------------------------------GSPLYM 329

  Fly   183 CHLCHLTFETPHPLKIHLALGCG---RSAMDILWMRLHYALKAAARSHTETQHSPIPATSSTSSA 244
            |..||:.:..|..|::|| :|..   |...||....|       .|....|:|
  Fly   330 CPECHVAYPEPELLEVHL-VGHNLEKRYVCDICQASL-------KRKDHLTRH------------ 374

  Fly   245 SPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTTAATPLSYLPSMSMATAPLSTNPMNAAAQIEA 309
            ..:|:|.          ||
  Fly   375 KQSHNPE----------RP---------------------------------------------- 383

  Fly   310 IVSNMGASKQGHLCIYCGKVYSRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLNKHVRLHL 372
                       ::|..|.|.:.||..|.:|...|:|.|..:|..|.:.|....:|.||.|.|:
  Fly   384 -----------YICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRSHI 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prdm13	NP_648032.1	COG5048	280..>380	CDD:227381	18/93 (19%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		zf-H2C2_2	336..358	CDD:290200	7/21 (33%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-C2H2	406..427	CDD:278523
		C2H2 Zn finger	408..427	CDD:275368
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	7/20 (35%)
		COG5048	356..>412	CDD:227381	20/141 (14%)
		C2H2 Zn finger	358..378	CDD:275368	6/38 (16%)
		zf-H2C2_2	370..395	CDD:290200	9/103 (9%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-H2C2_2	399..423	CDD:290200	8/23 (35%)
		zf-C2H2	412..434	CDD:278523	7/21 (33%)
		C2H2 Zn finger	414..434	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100