DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prdm13 and CG4282

DIOPT Version :9

Sequence 1:NP_648032.1 Gene:Prdm13 / 38713 FlyBaseID:FBgn0035687 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_611118.3 Gene:CG4282 / 36825 FlyBaseID:FBgn0034114 Length:652 Species:Drosophila melanogaster


Alignment Length:470 Identity:86/470 - (18%)
Similarity:148/470 - (31%) Gaps:150/470 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 TSMTTSSTETTLTATTSTASPAKRMRMSNPRPGVYASQYTPKDTCSMAIPTSALLG--------- 89
            :|:.....|..:..|...|.|.||...........|....||:...:.:....|..         
  Fly   175 SSVDKDKDEDGVEETAEPAPPKKRRGRPRKSDAAVAPPQKPKEDIQLDLKAEELDEFVDEETDPD 239

  Fly    90 -STVMPTDGSR------------SHCQLSNGE----LIVSGSLLRQIKLSEDVYSFNAIFELHGG 137
             |.::|:|.|.            |..:|.||:    ::...:::|..|..:         .....
  Fly   240 FSCLVPSDNSSEDDGGSDGFDSDSDFELDNGKQEFAVLPKRTVVRPKKYKK---------RTKPA 295

  Fly   138 QVRVRLVRDVARE--------DEIVAWFGEELVLLMGIPFLTPLNIQGNSRYMCHLCHLTFETPH 194
            :.:||:.|::..:        |.|:|.|           |.:.|        .|.:|:|......
  Fly   296 EPKVRMSRELLEQRKKQQEEYDVIIAKF-----------FTSVL--------PCAICNLLVHNFT 341

  Fly   195 PLKIHLALG----------CGRS-------AMDIL--WMRLHYALKAAARSHTETQHSPIPATSS 240
            .::.|..|.          |||.       |..:|  |...|:......:|...::|        
  Fly   342 EMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRH-------- 398

  Fly   241 TSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVT-TAATPLSY------LPSMSMA-TAPLS 297
            ..|....|            ..|...||.|..:...| .:.|.:.|      :|..... |....
  Fly   399 LESHQQVH------------MDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSEC 451

  Fly   298 TNPMNAAAQIEAIVSNMGASKQGHLCIYCGKVYSRKYGLKIHIRTHTGFKP------LKCKFCLR 356
            ........:::..:|:|...:...:|..|||....|..||.|.......||      .:|:.|..
  Fly   452 NKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGA 516

  Fly   357 PFGDPSNLNKHVR-LHLQTHPSSSAGVADGGASGADMDGDVDIEGETDADYQCHVCHKSFPRRRD 420
            .....:.|.:|:: :|::     |||                       :::||:|.|..|..|.
  Fly   517 WLKGMTGLKQHMKSIHVE-----SAG-----------------------EHRCHICAKVSPNARA 553

  Fly   421 LQRHMETRHGGHHSH 435
            |:||:      :|:|
  Fly   554 LRRHI------YHNH 562

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prdm13NP_648032.1 COG5048 280..>380 CDD:227381 21/113 (19%)
C2H2 Zn finger 323..343 CDD:275368 8/19 (42%)
zf-H2C2_2 336..358 CDD:290200 7/27 (26%)
C2H2 Zn finger 351..371 CDD:275368 4/20 (20%)
zf-C2H2 406..427 CDD:278523 9/20 (45%)
C2H2 Zn finger 408..427 CDD:275368 9/18 (50%)
CG4282NP_611118.3 zf-AD 7..81 CDD:285071
FYDLN_acid <191..268 CDD:302856 13/76 (17%)
C2H2 Zn finger 330..351 CDD:275368 5/20 (25%)
C2H2 Zn finger 360..378 CDD:275368 5/17 (29%)
LIM 361..>400 CDD:295319 9/46 (20%)
C2H2 Zn finger 386..406 CDD:275368 3/27 (11%)
zf-C2H2_8 389..465 CDD:292531 13/95 (14%)
C2H2 Zn finger 417..438 CDD:275368 3/20 (15%)
C2H2 Zn finger 448..465 CDD:275368 0/16 (0%)
C2H2 Zn finger 477..498 CDD:275368 8/20 (40%)
C2H2 Zn finger 511..532 CDD:275368 4/20 (20%)
C2H2 Zn finger 541..562 CDD:275368 10/26 (38%)
C2H2 Zn finger 570..590 CDD:275368
C2H2 Zn finger 598..619 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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